Phytochemical Screening of Leucosyke capitellata POIR and Dendrocnide densiflora C. B. ROB Plant in preference of its utilization in the Municipality of San Miguel, Surigao del Sur, Philippines

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Research Paper 01/03/2022
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Phytochemical Screening of Leucosyke capitellata POIR and Dendrocnide densiflora C. B. ROB Plant in preference of its utilization in the Municipality of San Miguel, Surigao del Sur, Philippines

Abstract

The discovery of plant containing secondary metabolites or commonly known as phytochemicals gain interests nowadays because it offers benefit of treating diseases. Most of the indigenous people are advocating the use of plant extracts to treat diseases without knowing its properties but because they have done it for more than a year and for them it was effective. Hence, this paper aims to investigate two plants utilized in the Municipality of San Miguel, Surigao del Sur namely: Leucosyke capitellata POIR. and Dendrocnide densiflora C.B.ROB commonly known as alagasi and sagay respectively. Roots of each plants were collected and were subjected for ethanolic extraction. Three extracts, (1) L. capitellata, (2) D. densiflora, and combined formulation with 1:1 ratio was subjected for qualitative phytochemical tests to detect the presence of bioactive compounds. Findings of the study revealed that the following bioactive constituents are present in the three extracts namely: saponins, flavonoids, tannins, and steroids. The presence of this secondary metabolites may be the reason to support its therapeutic value to the local healers to treat inflamed wounds. Richer amount L. capitellata bioactive constituents supports the most preferred utilization among local healers. Combined formulations of these plants were found to contain rich amount of its constituents which may be the reason why most of the healers practiced mixing root samples in their traditional medication. Furthermore, there is a need to explore more of its therapeutic value since they possess secondary metabolites that offer more than the present therapeutic utilization.

VIEWS 358

Ahmedulla M, Nayar MP. 1999. Red data book of Indian plants: Calcutta: Botanical Survey of India. p.4.

Arora DS, Kaur J. 1999. Antimicrobial activity of spices. International Journal of Antimicrobial Agents 12 (3), 257-262.

Awuchi CG. 2019. Medicinal plants: the medical, food, and nutritional biochemistry and uses. International Journal of Advanced Academic Research 5 (11), 220-241.

Balangcod TD, Vallejo VL, Patacsil M, Apostol O, Laruan LA, Manuel J, Cortez, S, Gutierrez RM. 2012. Phytochemical screening and antibacterial activity of selected medicinal plants of bayabas, Sablan Benguet Province Cordillera Administrative Region Luzon Philippines. Indian Journal of Traditional Knowledge 11 (4), 580-585.

Banag-Moran CI, Bautista FA, Bonifacio KAM, De Guzman CL, Lim JL, Tandang DN, Dagamac, NA. 2020. Variations in floristic composition and community structure between disturbed and undisturbed lowland forest in Aklan, Philippines. Geology, Ecology, and Landscapes pp. 1-10.

Catublas H. 2016. Knowledge, attitudes and practices in the use of herbal medicine: the case of urban and rural others in the Philippines. Mahidol University Journal of Pharmaceutical Sciences 43 (1), 1-16.

Chawla AS, Handa SS, Sharma, Kaith BS. 1987. Plant anti-inflammatory agents. Journal of Scientific and Industrial Research 46, 214 – 223.

Chen SL, Yu H, Luo HM, Wu Q, Li CF, Steinmetz A. 2016. Conservation and sustainable use of medicinal plants: problems, progress, and prospects. Chinese Medicine 11, 37.

Chiocchio I, Mandrone M, Tomasi P, Marincich L, Poli F. 2021. Plant secondary metabolites: An opportunity for circular economy. Molecules 26 (2), 495.

Cowan MM. 1999. Plant products as antimicrobial agents. Clinical Microbiology Reviews 12 (4), 564-582.

Edeoga HO, Okwu DE, Mbaebie BO. 2005. Phytochemical constituents of some Nigerian medicinal plants. African Journal of Biotechnology 4 (7), 685-688.

Ekor M. 2014. The growing use of herbal medicines: issues relating to adverse reactions and challenges in monitoring safety. Frontiers in Pharmacology 4 (177), 1-10.

Fajardo WT, Cancino LT, De Guzman SS, Macayana FB. 2017. Phytochemical screening of selected ethnomedicinal plants of Bolinao, Pangasinan, Northern Philippines. PSU Journal of Natural and Allied Sciences 1 (1), 38-46.

Gorlenko CL, Kiselev HY, Budanova EV, Zamyatnin AA, Ikryannikova LN. 2020. Plant secondary metabolites in the battle of drugs and drug-resistant bacteria: new heroes or worse clones of antibiotics?. Antibiotics (Basel) 9 (4), 170.

Guevarra BQ. 2005. A guidebook to plant screening phytochemical and biological, (UST Publishing House, Philippines).

Kolodziej H, Kiderlen AF. 2005. Antileishmanial activity and immune modulatory effects of tannins and related compounds on Leishmania parasitized RAW 264.7 cells. Phytochemistry 66 (77), 2065-2071.

Lagunay RE, Uy MM. 2015. Evaluation of the phytochemical constituents of the leaves of Ficus minahassae Tesym & De Vr., Casuarina equisetifolia Linn., Leucosyke capitellata (Pior) Wedd., Cassia sophera Linn., Derris elliptica Benth., Cyperus brevifolius (Rottb.) Hassk., Piper abbreviatum Opiz., Ixora chinensis Lam., Leea aculeata Blume, and Drymoglossum piloselloides Linn. Advances in Agriculture & Botanics-International Journal of the Bioflux Society (AAB Bioflux Society) 7(1), 51-58.

Li Y, Kong D, Fu Y, Sussman MR, Wu H. 2020. The effect of developmental and environmental factors on secondary metabolites in medicinal plants. Plant Physiology and Biochemistry 148, 80-89.

Montero JC, Geducos DT. 2021. Ethnomedicinal plants used by the local folks in two selected villages of San Miguel, Surigao del Sur, Mindanao, Philippines. International Journal of Agricultural Technology 17 (1), 193-212.

Pajarillaga LM, Aquino JDC, Undan JR. 2018. DNA barcoding and phytochemical profiling of wild plant “Lal lat tan” from Imugan, Sta Fe Nueva Vizcaya Philippines. International Journal of Secondary Metabolites 5 (5), 353-361.

Requena Y, Kenner D. 1996. Botanical medicine: a European professional perspective, (Paradigm Publications), Brookline Massachusetts.

Rios J, Recio M. 2005. Medicinal plants and antimicrobial activity. Journal of Ethnopharmacology 100 (1-2), 80-84.

Sofowora A. 1982. Medicinal plants and traditional medicine in Africa, 1st ed, (John Wiley and Sons Ltd, New York). pp. 168-171.

Stauth D. 2007. Studies force new view on biology of flavonoids, Oregon State University, USA.

Trease GE, Evans MC. 1983. Textbook of pharmacognosy, 12th ed (Tindall, London) 343-383.

WHO. 2004. WHO Guidelines on safety monitoring of herbal medicines in pharmacovigilance systems, (Geneva, Switzerland).

Zain W, Ahmat N, Norizan NH, Nazri NAAM. 2011. The evaluation of antioxidant, antibacterial and structural identification activity of trimmer resveratrol from Malaysia’s dipterocapercea. Australian Journal of Basic and Applied Sciences 5(5), 926-929.