Preliminary phyto-chemical screening and comparative antioxidant potential of Alstonia scholaris leaves extracts

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Research Paper 01/10/2019
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Preliminary phyto-chemical screening and comparative antioxidant potential of Alstonia scholaris leaves extracts

Md. Tohidur Rahman, Md. Asadul Islam, Md. Abdul Jalil, Nazim Uddin Ahmed, Md. Abdurrahim, Md. Mahmudul Hassan Mondol, Ali Ahsan Muzahid, Md. Badrul Islam, ABM Hamidul Haque
Int. J. Biosci.15( 4), 161-171, October 2019.
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Yet to now natural products, or its’ derivatives are in service to humankind as the best source of molecules to control the pest and disease problems of human beings. The present work investigated total phenolic content, total flavonoid content, reducing power capacity, total antioxidant capacity, DPPH free radial scavenging activity of four different extracts of the plant A. scholaris which belongs to the family Apocynaceae. Total phenolic content (21.92± 0.13 mg GAE/g) and total flavonoid content (16.61± 0.06 mg CatE/g) were found to be highest in Dia-ion resin adsorbed fraction, and the same fraction showed the highest total antioxidant activity with absorbance 1.049±0.014 at 100 mg/mL as well as highest DPPH radical scavenging activity with IC50 value 24.90 mg/mL. The Iron reducing power of the different extractives and standard exhibited the following order: Ascorbic acid> DRAF > CLF > EAF > PEF and the total antioxidant activity of different extractives and standard exhibited the following order:  Ascorbic acid> DRAF > PEF > EAF > CLF.


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