Preliminary studies on antibacterial effect of some medicinal plants against urinary tract pathogens

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Research Paper 10/03/2024
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Preliminary studies on antibacterial effect of some medicinal plants against urinary tract pathogens

M. Kumar, L. Prince
Int. J. Biosci.24( 3), 157-162, March 2024.
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Medicinal plants have wide medicament application used to prevent and management of many ailments. These plants are used for primary health care in human communities who are deprived of modern medical care. Urinary tract infections (UTI) are most common form of bacterial infections, affecting people throughout their lifespan. Hence the present study to evaluate the antibacterial potential of folk medicine against Urinary tract infection causing pathogens. In the present study 25 urine samples were collected and from the samples totally 58 bacterial colonies were isolated, among the 58 colonies six dominant urinary tract bacterial pathogens were identified by using Biochemical and Morphological characters which were confirmed as Escherichia coli, Klebsiella pneumoniae, Proteus vulgaris, Pseudomonas aeruginosa, Staphylococcus aureus and Streptococcus pyogenes. The antibacterial activity of folk three medicinal plant extract such as Allium sativum, Allium cepa and Zingiber officinale, used against bacteria isolates. Compared with folk three medicinal plant extract the Allium sativum was effective to kill the all bacteria isolates. Hence the herbal drugs have to be subjected to extensive pharmacological, toxicological and clinical tests to confirm the prescribed status. Thus the ethnobotanical approach will be like a search for molecular diversity subjecting a wide variety of new molecules from plant sources and testing them with as many different tests as possible.


Bauer AW, Kirby WM, Sherris JC, Turck M. 1966. Antibiotic susceptibillity testing by a standardized single disc method. American journal of clinical pathology 45, 494-496.

Delappe N, Halloran FO, Fanning S, Freney GC, Chaesty TT, Carmical M. 2003. Antimicrobial resistance and genetic diversity of Shigella sonnei isolates of infection. Journal of Clinical Microbiology 41, 1919-1924.

Ekwenye UN, Elegalam NN. 2001. Antibacterial activity of ginger (Zingiber officinale Roscoe) and garlic (Allium sativum L.) extracts on Escherichia coli and Salmonella typhi. Journal of Molecular Medicine 1, 411-416.

Grubben GJH, Denton OA. 2004. Plant Resources of Trophical Africa II: Vegetables. Leiden, Wageningen, Backhuys Publishers, 667p.

Hooton TM, Scholes D, Hughes JP, Winter C, Roberts PL, Stapleton AE. 1996. Prospective study of risk factors for symptomatic urinary tract infection in young women. New England Journal of Medicine 335, 468-74.

Inabo HI, Obanibi HBJ. 2006. Antimicrobial susceptibility of some urinary tract clinical isolates to commonly used antibiotics. African Journal of Biotechnology 5, 487-489.

Iwu MW, Duncan AR, Okunji CO. 1999. New antimicrobials of plant origin. In perspectives on new crops and new uses Jannick. J. ASHA press, 457-462p.

Kreig RN, Holt GJ. 1984. In Bergey’s Manual of systematic Bateriology.  Willium and Wilkins co. Baltimore, 408-516p.

Kupersztoch PYM. 1981. Antibiotic resistance of gram negative bacteria in Mexico: Relationship to drug consumption. In: Molecular biology, pathogenesis and Ecology of Bacterial Plamids, 529-537p.

Leung AY, Foster S. 1996. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd Edition, John Wiley and Sons, Inc., New York.

Mac Faddin FJ. 1980. Biochemical tests for identification of medical Bacteria Vol-I, Williams and Wilkins co. Baltimore, USA, 518-538p.

Morris AK, Masterton RG. 2002. Antibiotic resistance surveillance: action for international studies. Journal of Antimicrobial Chemotherapy 49, 7-10.

Muhammad HS, Muhammad S. 2005. The use of Lawsonia inermis Linn. Henna in the management of burn wound infections. African Journal of Biotechnology 9, 934-937.

Neu HC. 1994. Emerging trends in antimicrobial resistance in surgical infection. European Journal of Surgery 573, 7-18.

Porter IA, Bordie J. 1969. Boric acid preservation of urine samples. British Medical Journal  2, 353-355.

Raju CB, Tiwari SC. 2004. Urinary tract infection-A suitable approach, Lecture notes. Journal, Indian Academy of Clinical Medicine 2, 331-334.

Ramdas K, Ramachandra RL, Padmalatha S. 2006. Antibacterial activity of the leaf extracts of Asparagus racemosus. Geobios 33, 279-280.

Sharma VD. 1977. Antimicobial property of Allium sativum Linn: In vivo and in vitro studies. Indian Journal of Experimental Biology 15, 466-468.

Sivakumar R, Alagesaboopathi C. 2006. Antimicrobial activity of two different forms of Abrus precatorius L. Academy of Plant Sciences 19, 409-413.

Soulsby EJ. 2005. Resistance to antimicrobials in humans and animals. Brazilian Journal of Medical and Biological Research 331, 1219-1220.

Tetyana P,  Pozesky EA, Jager AK. 2002. Some medicinal properties of Cussonia and schefflera species used in traditional medicine. South African Journal of Botany 68, 51-54.

Wang J, Galgici A, Kodali Herath SKB, Jayasuriya H, Dorso K, Vicente F, Gonzale A, Cully D, Bramhill D, Singh S. 2003. Discovery of a small molecule that inhibits cell division by blocking Fts Z a novel therapeutic target of antibiotics. The Journal of Biological Chemistry 278, 424-428.

Zar JH. 1984. In: Biostatistical Analysis, Englewood Cliffs, N. J.: Prentice hall, Inc, 437-467p.