Prevalence and associations of thyroid dysfunction with metabolic markers blood glucose and lipid profile: A cross-sectional study

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Research Paper 06/10/2023
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Prevalence and associations of thyroid dysfunction with metabolic markers blood glucose and lipid profile: A cross-sectional study

Aziz Ur Rehman, Faisal Khan, Muhammad Abbas, Abdullah, Ashfaq Ahmad, Kashif Ahmad, Syed Rabnawaz Shah, Abdur Rehman
Int. J. Biomol. & Biomed.17( 2), 7-12, October 2023.
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Abstract

Thyroid hormone contains two vital hormones. Triiodothyronine (T3) and thyroxine (T4), are necessary for regulating metabolism, including glucose homeostasis, lipid metabolism, and cholesterol synthesis. In this cross-study, a total of 199 patients both males and females included, investigated the interrelation between thyroid function test, lipid profile, and Random blood sugar which were shown to be significant because these are the main factor that affects thyroid hormone and data was analyzed using SPSS version 25. The results suggest that thyroid function plays a role in metabolic health. Furthermore, a significant relationship was identified between TSH and random blood sugar (RBS) that can cause hypoglycemia, indicating a potential link between thyroid function. The mean and standard deviation of T3 is 2.1 ± 2.5ng/ml, T4 3.8 ± 5.9 P mol/L, TSH 5.4 ± 13.3 PIU/ml, RBS 100 ± 45mg/dl which is on the lower limit, TG 200 ± 45mg/dl, Cholesterol 201 ± 25mg/dl are on upper limit can cause dyslipidemia. There is a negative association between TSH and random blood sugar with P< 0.05. These findings have implications for understanding thyroid disorders and their impact on metabolic health.

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