Prevalence and carriage status of Salmonella typhi among students of ekiti state university, Ado-Ekiti, Nigeria
Paper Details
Prevalence and carriage status of Salmonella typhi among students of ekiti state university, Ado-Ekiti, Nigeria
Abstract
The carriage of SalmonellaTyphi among Nigerian students is still very high due to very poor hygiene. In this study the prevalence, antibiotic susceptibility of SalmonellaTyphi from the stool of undergraduate students from a Nigeria university was investigated. Salmonella Typhi was isolated from stool samples from 510 subjects. Antibiotic susceptibility test of the isolates was carried out using disk diffusion method. The clinical data (Widal Test) from the University Health Centre records were also collected and analyzed in this study. Out of the isolates, 75.90 % were resistant to ceftazidime, 34.87 % to cefuroxime, 83.59 % to cefixime and 18.46 % to ofloxacin. SalmonellaTyphi isolated exhibited multiple resistance to at least three of the antibiotics tested. The carriage rate of the SalmonellaTyphi among undergraduate students of Ekiti State University, Ado-Ekiti was 33.86%. The clinical data showed the rate of the Salmonella infection among the undergraduate students to be 58.90%. From the clinical record of the University Health Centre, 935 (40.20%) and 1,391 (59.80%) of the students with symptoms of the enteric fever were male and females respectively and only 1370 tested positive to Salmonella antibody. There was a significant difference between the males and the females with the two tails, p-value = 0.023, F=2.931. The needs for proper educated and the good hygiene cannot be overemphasized.
Abera B, Biadegelgen F, Bezabih B. 2010. Prevalence of Salmonella typhiand intestinal parasites among food handlers in Bahir Dar Town, Northwest Ethiopia. Ethiopian Journal of Health Development24(1), 20-40. http://dx.doi.org/10.4314/ejhd.v24i1.62944
Akyala I, Tanimu H, Haruna Y. 2013. Antimicrobial susceptibility and drug resistance pattern of Salmonella species in two health centres in Nasarawa State, Nigeria. International Journal of Microbiology Research2, 011-016.
Anushtup DE, Prabal MS, Bashir B, Kaundal R, Kalra N. 2010. Transverse colon perforations in enteric fever. International Journal of Tropical Medicine5(3), 58-61. http://dx.doi.org/10.3923/ijtmed.2010.58.61
Anyebe EE, Opaluwa SA, Ajayi AD, Garba SN, Obiako OR, Alhassan E. 2008. The social and clinical correlates of typhoid fever infection in Zaria, northern Nigeria.Africa Journal of Nursing and Midwifery 10(1), 109-120.
Aoife M, Satheesh N, Fiona JC, Estee MT. 2010. First report of Salmonella entericaserotype paratyphi A Azithromycin resistance leading to treatment failure. Journal of Clinical Microbiology 48(12), 4655-4659. http://dx.doi.org/10.1128/jcm.00648-10
Barrow G, Feltham R. 1993. Cowan and Steel’s Manual for the Identification of Medical Bacteria, Cambridge University Press, 331 P.
Boyle EC, Bishop JL, Grassl GA, Finlay BB. 2007. Salmonella: from pathogenesis to therapeutics. Journal of Bacteriology189, 1489-1495. http://dx.doi.org/10.1128/jb.01730-06
Brooks GF, Butel JS, Ornston LN, Carroll KC, Morse SA. 2004. Jawetz, Melnick and Adelberg’s Medical Microbiology. The McGraw-Hill Companies Inc., 24th Ed.
Buchwald D, Blaser M. 2004. A review of human salmonellosis: Duration of excretion following infection with non-typhiSalmonella.Review of Infectious Diseases 6, 345–6.
Center for Disease Control and Prevention. 2005. Food-borne Illness Report. International Food Safety Consultancy. CDC 1-13 P.
Clinical and Laboratory Standards Institute. 2012. Performance Standards for Antimicrobial Susceptibility Testing; Twenty-Third Informational Supplement. Wayne, PA: CLSI Document M100-S23.
Dewan AM, Corner R, Hashizume M, Ongee ET. 2013. Typhoid fever and its association with environmental factors in the Dhaka Metropolitan area of Bangladesh: A spatial and time-series approach. PLoS Neglected Tropical Diseases. 7(1), 1-14. http://dx.doi.org/10.1371/journal.pntd.0001998
Dugid JP, North AE. 1991. Eggs and Salmonella food-poisoning: an evaluation. Journal of Medical Microbiology 34(2), 65-72. http://dx.doi.org/10.1099/00222615-34-2-65
European Food Safety Authority (EFSA). 2012. The European Union Summary Report on Trends and Sources of Zoonoses, Zoonotic Agents and Food-borne Outbreaks in 2010. EFSA Journal 10(3), 2597. http://dx.doi.org/10.2903/j.efsa.2012.2597
Getnet F. 2013. Isolation of Salmonella species among apparently healthy individuals of Addis Ababa University students, Addis Ababa, Ethiopia. Oai:localhost:12346789/3106
Gomez-Duartz OG, Abu-El-Haija MA, Sanchez-Vargas FM. 2011. Salmonella infections: An update on epidemiology, management and prevention. Travel Medicine of Infectious Diseases9, 263-277. http://dx.doi.org/10.101016/j.tmaid.2011.11.001
Gonzalez-Escobedo G, Gunn JS. 2013. Gallbladder epithelium as a niche for chronic Salmonella carriage. Infection and Immunology81(8), 2920-30. http://dx.doi.org/10.1128/IAI00258-13
Helms M, Vastrup P, Gerner-Smidt P, Molbak L. 2003. Short and long term mortality associated with foodborne bacterial gastrointestinal infections: registry based study. British Medical Journal 326, 1-5.
Ibekwe AC, Okonko IO, Onunkwo AU, Donbraye E, Babalola ET, Onoja BA. 2008. Baseline Salmonella agglutinintitres in apparently healthy freshmen in Aw ka, South Eastern, Nigeria. Science Research and Essay 3(9), 225-230.
Karshima NS, Pam VA, Bata SI, Dung PA, Paman ND. 2013. Isolation of Salmonella species from milk and locally processed milk products traded for human consumption and associated risk factors in Kanam, Plateau State, Nigeria. Journal of Animal Production Advances3(3), 69-74. http://dx.doi.org/10.5455/japa.20130330124355
Mead PS, Slutsker L, Dietz V, McCaig LF, Bresee JS, Shapiro C, Griffin PM, Tauxe RB. 1999. Food-related illness and death in the United States, Emergence of Infectious Diseases5, 607-625. http://dx.doi.org/10.3201/eid0505.990502
Muleta D, Ashenafi M. 2001. Salmonella, Shigella and growth potential of other food-borne pathogens in Ethiopia Street vended foods. East African Medical Journal 78(11), 576-580. http://dx.doi.org/10.4314/eamj.v78i11.8946
Olopoenia LA, King AI, Santanga FA. 2000. Classic methods revisited: Widal agglutination test 100 years later: still plagued by controversy. Postgraduate Medical Journal 76(892), 80-84. http://dx.doi.org/10.1136/pmj.76.892.80
World Health Organization. 2005. Global Salmonella-Surveillance Progress Report 2000-2005, Geneva.
World Health Organization. 2007. Food Safety and Food-Borne Illness; WHO Media Center Fact Sheet, Food Safety Department, Geneva.
O.M. David, D.A. Adedapo, D.D. Moro, C.O. Esan, O.J. Oje, O. Famurewa (2015), Prevalence and carriage status of Salmonella typhi among students of ekiti state university, Ado-Ekiti, Nigeria; IJB, V6, N10, May, P1-8
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