Prevalence and carriage status of Salmonella typhi among students of ekiti state university, Ado-Ekiti, Nigeria

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Research Paper 15/05/2015
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Prevalence and carriage status of Salmonella typhi among students of ekiti state university, Ado-Ekiti, Nigeria

O.M. David, D.A. Adedapo, D.D. Moro, C.O. Esan, O.J. Oje, O. Famurewa
Int. J. Biosci.6( 10), 1-8, May 2015.
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Abstract

The carriage of SalmonellaTyphi among Nigerian students is still very high due to very poor hygiene. In this study the prevalence, antibiotic susceptibility of SalmonellaTyphi from the stool of undergraduate students from a Nigeria university was investigated. Salmonella Typhi was isolated from stool samples from 510 subjects. Antibiotic susceptibility test of the isolates was carried out using disk diffusion method. The clinical data (Widal Test) from the University Health Centre records were also collected and analyzed in this study. Out of the isolates, 75.90 % were resistant to ceftazidime, 34.87 % to cefuroxime, 83.59 % to cefixime and 18.46 % to ofloxacin. SalmonellaTyphi isolated exhibited multiple resistance to at least three of the antibiotics tested. The carriage rate of the SalmonellaTyphi among undergraduate students of Ekiti State University, Ado-Ekiti was 33.86%. The clinical data showed the rate of the Salmonella infection among the undergraduate students to be 58.90%. From the clinical record of the University Health Centre, 935 (40.20%) and 1,391 (59.80%) of the students with symptoms of the enteric fever were male and females respectively and only 1370 tested positive to Salmonella antibody. There was a significant difference between the males and the females with the two tails, p-value = 0.023, F=2.931. The needs for proper educated and the good hygiene cannot be overemphasized.

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