Prevalence and comparative analysis of HBs, HCV, CRP, T.B and H. pylori in drug addicted individuals from local population of Charsadda, Khyber Pakhtunkhwa, Pakistan

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Research Paper 01/04/2018
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Prevalence and comparative analysis of HBs, HCV, CRP, T.B and H. pylori in drug addicted individuals from local population of Charsadda, Khyber Pakhtunkhwa, Pakistan

Hasnain Jan, Ayesha Naeem, Sajjad Ali Shah, Wali Muhammad, Muhammad Asad Ullah, Shah Faisal, Hazrat Usman, Ayyaz Khan, Sifatullah
Int. J. Biosci.12( 4), 433-441, April 2018.
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Abstract

The main objective of the current study was to evaluate the prevalence of infectious diseases in drug addicts compared to normal individuals. The study was conducted in Biotechnology Department Bacha Khan University Charsadda, KPK, Pakistan. Total 80 drug addict’s blood samples including smoker, alcoholic, cocaine and cannabis users (20 of each) were collected from age range 25-50 years from local area in EDTA tube and multiple diagnostic assay were performed. Results indicated that total of 22.5% HBs, 50% HCV, 17.5% CRP, 18.5% T.B and 65% H. pylori prevalence was found in each drug category. The results suggested an interaction on the additive scale between drugs use and HBV infection, and an interaction on the multiplicative scale with HCV infection. Additional studies are required to investigate the possible biological role of drugs in the development of infectious forms of HBs, HCV, CRP, T.B and H. Pylori and effect on expression of gene and DNA of addicted individuals. There is dire need of awareness in public about the lethal effects of use of these addictive drugs.

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