Prevalence and Treatment Outcome of Smear Positive Pulmonary Tuberculosis Patients in General Population of District Swat, Pakistan

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Research Paper 01/11/2021
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Prevalence and Treatment Outcome of Smear Positive Pulmonary Tuberculosis Patients in General Population of District Swat, Pakistan

Shah Hassan Khan, Inam Ullah, Zakir Ullah, Zahir Shah, Khalid Jamal, Ikram Ullah
Int. J. Biosci. 19(5), 54-59, November 2021.
Copyright Statement: Copyright 2021; The Author(s).
License: CC BY-NC 4.0

Abstract

Mycobacterium tuberculosis is responsible for causing TB disease. Primarily it infects the lungs, which is known as pulmonary tuberculosis when the disease disseminates to other parts of the body known as extra-pulmonary tuberculosis. Recently, WHO ranked Pakistan the fifth TB endemic country in the world. The objective of this study was to evaluate the prevalence and treatment outcome of smear-positive PTB patients among all forms of TB registered with TB centre at District swat. Two-year data from January 2016 to December 2017 were reviewed. In this study period, complete information of total 1392 cases of pulmonary tuberculosis (PTB) were reviewed. Of these, 626(45%) were founded to be males, while 766(55%) were females with an overall mean age of 32.9 years. In the age-wise distribution, this study showed a high number of cases, 657(47.3%) in the economic age group from 16-30. In contrast, the lowest number of cases, 112(8%), were recorded in the 60 years older adults. Of the two-year study period, 745(53.5%) patients were recorded in 2017, while 647(46.5%) patients were recorded in 2016. The overall prevalence rate in the 100,000 population was calculated to be 58.8(0.058%). Based on seasonality, high cases notification was reported in quarter 2 (April- June), while lower cases notification was recorded in quarter 4 (October-December). Treatment outcome record showed that 861(61.9%) were cured, 452(32.5%) treatment completed, 34(2.4%) died, 13(0.9%) treatment failed, 32 (2.3%) lost to follow up, and no patient was transferred to other facilities. In conclusion, still, PTB is prevalent in the district, and the overall treatment success rate is low.

Abebe G, Zegeye Bonsa WK. 2017. Treatment Outcomes and Associated Factors in Tuberculosis Patients at Jimma University Medical Center: A 5‑Year Retrospective Study Gemeda. International Journal of Mycobacteriology 6(3), 239–245. https://doi.org/10.4103/ijmy.ijmy

Ahmad T, Ahmad K, Ur Rehman MM, Khan A, Jadoon MA, Ur Rehman MN, Akif FA, Naz BS, Khan S, Ullah A. 2014. Tuberculosis is still a prevalent disease in population of district dir (Lower) Khyber Pakhtunkhwa Pakistan. Global Veterinaria, 12(1), 125–128. https://doi.org/10.5829/idosi.gv.2014.12.01.82277

Ahmad T, Jadoon MA. 2015. Cross Sectional Study of Pulmonary Tuberculosis at Civil Hospital Thana, District Malakand Khyber Pakhtunkhwa Pakistan. World Journal of Zoology 10(3), 161–167. https://doi.org/10.5829/idosi.wjz.2015.10.3.9578

Ahmad T, Majid A, Ullah N, Ullah T. 2016. Treatment Outcomes of Suspected Tuberculosis Patients At Civil Hospital Barikot Swat, Pakistan :(a Case study ). Science International 28(1), 423–425.

Ali MK, Karanja S, Karama M. 2017. Factors associated with tuberculosis treatment outcomes among tuberculosis patients attending tuberculosis treatment centres in 2016-2017 in Mogadishu, Somalia. Pan African Medical Journal 28, 1–14. https://doi.org/10.11604/pamj.2017.28.197.13439

Allotey P, Gyapong M. 2008. Gender in tuberculosis research. International Journal of Tuberculosis and Lung Disease 12(7), 831–836.

Atre SR, Kudale AM, Morankar SN, Rangan SG, Weiss MG. 2004. Cultural concepts of tuberculosis and gender among the general population without tuberculosis in rural Maharashtra, India. Tropical Medicine and International Health, 9(11), 1228–1238. https://doi.org/10.1111/j.1365-3156.2004.01321.x

Cambau E, Drancourt M. 2014. Steps towards the discovery of Mycobacterium tuberculosis by Robert Koch, 1882. Clinical Microbiology and Infection 20(3), 196–201. https://doi.org/10.1111/1469-0691.12555

Fares A. 2011. Seasonality of tuberculosis. Journal of Global Infectious Diseases 3(1), 46–55. https://doi.org/10.4103/0974-777X.77296

Gashu Z, Jerene D, Datiko DG, Hiruy N, Negash S, Melkieneh K, Bekele D, Nigussie G, Suarez PG, Hadgu A. 2018. Seasonal patterns of tuberculosis case notification in the tropics of Africa: A six-year trend analysis in Ethiopia. PLoS ONE, 13(11), 1–12. https://doi.org/10.1371/journal.pone.0207552

Hershkovitz I, Donoghue HD, Minnikin DE, Besra GS, Lee OYC, Gernaey AM, Galili E, Eshed V, Greenblatt CL, Lemma E, Bar-Gal G. K, Spigelman M. 2008. Detection and molecular characterization of 9000-year-old Mycobacterium tuberculosis from a neolithic settlement in the Eastern mediterranean.PLoS ONE 3(10), 1–6. https://doi.org/10.1371/journal.pone.0003426

Kesete Y. 2020. Assessment of the Prevalence of Pulmonary Tuberculosis Patients at Nakfa Hospital from 2014-2019, Eritrea. 5–9. https://doi.org/10.1101/2020.02.11.20021279

Ukwaja KN, Ifebunandu NA, Osakwe PC, Alobu I. 2013. Tuberculosis treatment outcome and its determinants in a tertiary care setting in south-eastern Nigeria. The Nigerian Postgraduate Medical Journal 20(2), 125–129.

WHO. 2010. Gobal Tuberculosis Report 2010. Genva: World Health Organization.     https://apps.who.int/iris/handle/10665/44425/Accessed September 5 2021

WHO. 2016. Global Tuberculosis Report 2016. Genva: World Health Organization. Accessed September 25, 2021. https://apps.who.int/iris/handle/10665/250441/

WHO. 2017. Global Tuberculosis Repport 2017. Genva: World Health Organization. Accessed September 20 2021. https://apps.who.int/iris/handle/10665/259366/

WHO. 2019. Global Tuberculosis Report 2019. Genva: World Health Organization. Accessed September 12, 2021. https://apps.who.int/iris/bitstream/handle/10665/329368/9789241565714-eng.pdf?ua=1/

WHO. 2020. Global Tuberculosis Report 2020. Genva: World Health Organization. Accessed September 10, 2021. https://apps.who.int/iris/bitstream/handle/10665/336069/9789240013131-eng.pdf/

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