Prevalence, factors and complication of Diabetes in an underdeveloped Region of Khyber Pukhtun Khawa: A cross-sectional study

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Research Paper 03/12/2023
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Prevalence, factors and complication of Diabetes in an underdeveloped Region of Khyber Pukhtun Khawa: A cross-sectional study

Fazal Shan, Sajid Ali, Imad Ud Din, Majid Ullah, Hamza Ali, Hammad Rashid, Hassan Khan, Rafi Ullah, Arbaz Khan, Muhammad Khalid Khan, Imad Khan
Int. J. Biomol. & Biomed.17( 3), 1-6, December 2023.
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This cross-sectional study aimed to investigate the prevalence and associated factors of diabetes in an underdeveloped region. The study was conducted over a four-month period, involving 409 participants from a specific region in Pakistan. Data on demographic characteristics, clinical variables, and risk factors were collected using questionnaires and laboratory tests. Statistical analysis was performed to determine prevalence rates and assess associations between variables. The study revealed a high prevalence of diabetes, with 22.49% of the participants diagnosed as hyperglycemic. The prevalence of diabetes was found to be higher in males compared to females. Risk factors such as obesity, hypertension, and positive family history were significantly associated with diabetes. Various diabetes-related complications, including retinopathy, gestational diabetes mellitus, periodontal disease, diabetic nephropathy, and heart disease, were identified among the participants. This study highlights the alarming burden of diabetes in the studied underdeveloped region. The higher prevalence of diabetes in males, the association with risk factors, and the presence of diabetes-related complications underscore the need for urgent public health awareness campaigns. Early diagnosis, treatment, and preventive measures are crucial to mitigate the increasing prevalence of diabetes. Further research and interventions are required to effectively manage and reduce the burden of diabetes in underdeveloped regions.


Abbott C, Carrington A, Ashe H, Bath S, Every L, Griffiths J, Hann A, Hussein A, Jackson N,  Johnson K. 2002. The North‐West Diabetes Foot Care Study: incidence of, and risk factors for, new diabetic foot ulceration in a community‐based patient cohort. Diabetic medicine 19, 377-384.

Association AD. 2010. Standards of medical care in diabetes- 2010. Diabetes care 33, S11.

Badawi A, Klip A, Haddad P, Cole DE, Bailo BG, El-Sohemy A, Karmali M. 2010. Type 2 diabetes mellitus and inflammation: Prospects for biomarkers of risk and nutritional intervention. Diabetes, metabolic syndrome and obesity: targets and therapy 173-186.

Basit A, Fawwad A, Qureshi HN. 2018. Correction: Prevalence of diabetes, pre-diabetes and associated risk factors: second National Diabetes Survey of Pakistan (NDSP) 2016–2017.

Chiwanga FS, Njelekela MA, Diamond MB, Bajunirwe F, Guwatudde D, Nankya-Mutyoba J, Kalyesubula R, Adebamowo C, Ajayi I, Reid TG. 2016. Urban and rural prevalence of diabetes and pre-diabetes and risk factors associated with diabetes in Tanzania and Uganda. Global health action, 9, 31440.

Danquah I, Bedu-Addo G, Terpe KJ, Micah F, Amoako YA, Awuku YA, Dietz E, Van Der Giet M, Spranger J, Mockenhaupt FP. 2012. Diabetes mellitus type 2 in urban Ghana: characteristics and associated factors. BMC public health 12, 1-8.

Divers J, Mayer-Davis EJ, Lawrence JM, Isom S, Dabelea D, Dolan L, Imperatore G, Marcovina S, Pettitt DJ, Pihoker C. 2020. Trends in incidence of type 1 and type 2 diabetes among youths-selected counties and Indian reservations, United States, 2002-2015. Morbidity and Mortality Weekly Report 69, 161.

Forouhi NG, Wareham NJ. 2019. Epidemiology of diabetes. Medicine 47, 22-27.

Harrison TA, Hindorff LA, Kim H, Wines RC, Bowen DJ, Mcgrath BB, Edwards KL. 2003. Family history of diabetes as a potential public health tool. American journal of preventive medicine 24, 152-159.

Herman WH. 2017. The global burden of diabetes: an overview. Diabetes mellitus in developing countries and underserved communities 1-5.

Kaul K, Tarr JM, Ahmad SI, Kohner EM, Chibber R. 2013. Introduction to diabetes mellitus. Diabetes: an old disease, a new insight 1-11.

Ramachandran A. 2014. Know the signs and symptoms of diabetes. The Indian journal of medical research 140, 579.

Saeedi P, Petersohn I, Salpea P, Malanda B, Karuranga S, Unwin N, Colagiuri S, Guariguata L, Motala AA, Ogurtsova K, Shaw JE, Bright D, Williams R. 2019. Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: Results from the International Diabetes Federation Diabetes Atlas, 9(th) edition. Diabetes Res Clin Pract 157, 107843.

Stanifer JW, Cleland CR, Makuka GJ, Egger JR, Maro V, Maro H, Karia F, Patel UD, Burton MJ, Philippin H. 2016. Prevalence, risk factors, and complications of diabetes in the Kilimanjaro region: a population-based study from Tanzania. PloS one 11, e0164428.

Whiting DR, Guariguata L, Weil C, Shaw J. 2011. IDF diabetes atlas: global estimates of the prevalence of diabetes for 2011 and 2030. Diabetes research and clinical practice 94, 311-321.

WHO. 2016. Global Report on Diabetes [Online].