Prevalence of hepatitis B virus transmission from mother-to-child in Parturient women in Plateau State, Nigeria

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Research Paper 27/07/2023
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Prevalence of hepatitis B virus transmission from mother-to-child in Parturient women in Plateau State, Nigeria

TS. Vem, J. Anejo-okopi, EM. Agbo, Y. Agabi, KM. Thomas, DM. Maktu, P. Lar
Int. J. Micro. Myco.17( 1), 1-13, July 2023.
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High prevalence of hepatitis B virus (HBV) infection in parturient women is the primary source of infection for their children and the general population. Mother-to-child transmission (MTCT) is the primary mode of transmission in endemic areas. The aim of this study is to determine the prevalence rate of MTCT of HBV in parturient women in Plateau state, north central Nigeria, and associated risk factors among delivering mothers. This health facility-based cross-sectional study was conducted in different hospitals covering the three (3) senatorial zones of Plateau state among 260 parturient women. Structured questionnaires and laboratory results were used to collect the data. The data were checked for completeness and entered into the statistical package for social science (SPSS) version 26 software versions. Significant association was considered at p < 0.05. A total of 260 mothers were enrolled. The prevalence rate of HBV infection among the parturient women and the rate of MTCT of the infection were 9.2% and 25.0%, respectively. Among 260 parturient women, only 12.7 (9.1%) had a history of multiple sexual partners, of which 18.2% were positive for HBsAg. There was no Statistically significant association between HBV infection and having multiple sexual partners (p = 0.193). HBV infection among parturient women has become highly endemic, and the rate of MTCT is high. Therefore, administering hepatitis B vaccine to all neonates within 24 h of birth is mandatory to prevent MTCT of HBV infection and related complications.


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