Int. J. Biosci.3( 3), 142-154, March 2013
A survey prevalence of Hepatitis C Virus (HCV) Patients in Parachinar, Kurrum Agency , Pakistan was performed from March 2010 to March 2011. 100 positive HCV cases were selected and interviewed. The highest prevalence of HCV was found in 36% males and 8% females with aged 16-30 years. HCV infection in married 55% males and 10% females. Population in rural area was more affected as in males 72% and females 10%. Socioeconomic condition of the cases belongs to business class people, in which 74% male and 7% females +ve. Risk factors of HCV patients from higher to lower range as share syringe were found in males 31% and females 7%, patients with surgical operations were in males 17% and females 12%. Health care workers, in 14% males and no female was affected. Sexually transmission of HCV, in males 3% and females 2%. Symptoms of HCV found in patients with descending order: abdominal pain in males 67% and females 12%; fatigue in males 65% and females 12%; fever in males 64% and females 6%; yellow skin color in males 53% and females 7%; dark color urine in males 35% and females 7%; rashes in males 35% and females 6%; vomiting in males 21% and females 4%; pale color stool in males 19% and females 5%. The HCV was diagnosed by strip, ELISA and PCR methods. Strip method was performed by males 9% and females 3%. The ELISA was performed by 74% males and 9% females while PCR was performed by only 2% males.
Agnello V, Abel G, Elfahal M, Knight GB, Zhang QX. 1999. Hepatitis C Virus and other flaviviridae viruses enter cells via low density lipoprotein receptor. National Academic Sciences USA 96, 12766-12771.
Ali R, Yazdi A, Panahi M. 2004. Prevalence of blood borne infections among imprisoned injecting drug users in Mashhad North east of Iran. Journal of Iranian Medicine 7, 190-194.
Alter MJ, Moron DK, Nainan OV, McQullan GM, Gao F, Moyer LA, Kaslow RA, Margolis H S. 1999. Prevalence of hepatitis C virus infection in the United States, 1994. Journal of Medical science 341, 556-562.
Balogun MA, Ramsay ME, Hesketh LM, Audiews N, Osborne KP, Capner PM 2002. Prevalence of hepatitis C in England and Wales. Journal of Epidemiology Infection 45(4), 219-226.
Bhatti M, Tariq. 1996. Epidemiology of Hepatitis C virus in blood donors in Northern Pakistan. Society of Gastroenterology, Rawalpindi 68(6), 21-35
Brook S, Schaim SN, Fattovich G, Bronwer TJ. 1989. Therapy of hepatitis C patients with cirrhosis. Journal of Hepatology 26(3), 1285-1325.
Chang CH, Lu FC, Chiu HY, Chen JC. 2001. Risk factors associated with hepatitis C virus infection in Taiwanese government employees. Journal of Epidemiology Infection 126, 291-299.
Choudhary A, Santra A, Chaudhuri S, Dhali GP, Chaudhuri S, Maity SG, Naik TN, Bhattacharya SK, Mazumder DNG. 2003. Hepatitis C virus infection in the general population a community based study in West Bengal, India. Journal of Hepatology 37(4), 802-809.
Crofts N, Thompson S, Kaldor J. 1999. Epidemiology of the hepatitis C virus Technical Report Series. Journal of Clinical Microbiology 3, 1-13.
Desenclos JC, Madhava V, Burgess C, Drucker E. 2000. Epidemiology of hepatitis C 50(10), 1066-1070.
Hussain W. 2007. File to medicinal study of Upper Kurram Agency. M. phil thesis Department of Botany, Kohat University of Science and Technology 13-17.
Khan AA, Ahmad H, Ghafoor US, Begum K, Khan AI. 2010. Frequency distribution of hepatitis in three districts of Hazara Division. Asian Journal 45, 16-19.
Khattak MF, Salamat N, Bhatti FA, Qureshi TZ. 2002. Prevalence of hepatitis B, C and HIV in blood donors in northern Pakistan. Journal of Pakistan Medical Association 52(9), 398-402.
Malik IA, Ahmed N, Luqman M. 1992. Hepatitis virus cause of chronic liver diseases in Northern Pakistan. Journal of Pakistan Medical Association 42, 67-73.
McCormick BJ, Hoch PSF. 1999. Emerging diseases in the 2lst century Edwin C Yoder Lecture, Tacoma, Wash 112-123.
McInnis-Shaw V. 2003. Overview of Hepatitis C virus. Journal of Hepatitis Central 345, 379-386.
Mohammed A, Medhat AN, Shehata M, Nabiel N, Mikhail H, Swifee Y, Hamid MA, Watts S, Alan D, Fix G, Strickland T, Anwar W. 2000. Hepatitis C in a community of Upper Egypt, cross- sectional survey. Journal of Medical Hygiene 63(5), 236-241.
Montalto G, Cevello M, Giannitrapani L, Dantona F, Terranova A, Gastagneta LA. 2002. Epidemiology, Risk factors and natural biopsy of hepatocellular carcinoma and alpha tyrpsin deficiency. Army academic Sciences 963, 12-20.
Nishiguch Tio, Shihiro. 1994. StrategInicd usttial Sourag The JapaneAsdev antage Oxford 196-197.
Poynard T, Mousalli J, Tbevenot T, Ratzui V, Opolon P. 1998. Treatment of chronic hepatitis C with Interferon therapies of viral hepatitis. International Medical Press 371-378.
Raffacle A, Valenti M, lovenitti M, Matani A, Bruno ML, Altobelli ED, Alessandro A, Leonardis B, Taglieri G. 2001. High prevalence of HCV infection among the general population in a rural area of central Italy Euro Journal of Epidemiology 17(1), 41-49.
Roy K, Hay C, Andragetti R, Taylor A, Goldberg D, Wiessing L. 2002. Monitoring hepatitis C virus infection among drug users in the European Union, a review of the literature. Epidemiology Infection 129(3), 577-585.
Tariq WUZ, Hussain AB, Karamat KA, Ghani E, Mustaq S, Hussain T. 1998. HCV viremia in clinical and biochemical prospective. Proceeding of seminar AFIP, Rawalpindi, Islamabad 46-49.
Taylor DR, Shi ST, Romano PR, Barber GN, Lai MMC. 1999. Inhibition of the interferon inducible protein kinase PKR by HCV E2 protein. Journal of Medical Science 285, 107-110.
Wang CJ, Chang YJ, Yeh L, Chang TT. 2002. Endemic hepatitis C virus infection in a seaboard village of south western Taiwan. Journal of Nurse10(4), 246-252.