home icon user icon
Welcome to International Network for Natural Sciences | INNS Pub.
Home My Account
Submit Manuscript
double_slash
breadcumb_bg

Prevalence of metabolic syndrome in patients admitted to the national cardiac center of Benghazi, Libya

Paper Details

Research Paper 10/11/2024
Views (39) Download (18)
current_issue_feature_image
publication_file

Prevalence of metabolic syndrome in patients admitted to the national cardiac center of Benghazi, Libya

Mohamed Najah, Shahd Maftah, Reem Moussa, Salah Mohamed Abdallah, Ali Almugrby, Hatem Rajab Mohamed, Hussein Hamid, Mohamed H. S. Ahmida, Abdulla Mohammed Elmansoury
Int. J. Biosci.25( 5), 199-206, November 2024.
Certificate: IJB 2024 [Generate Certificate]
Key: Cardiovascular diseaseHypertensionMetabolic syndromeObesity

Abstract

Metabolic syndrome (Mets) represents a constellation of metabolic disorders, including diabetes mellitus, obesity, dyslipidemia, and hypertension. Since it is associated with different risk factors of cardiovascular diseases (CVD), studying its prevalence is important. The main objective of this work was to find out the prevalence of metabolic syndrome and to characterize its presence among cardiovascular patients admitted to the National Cardiac Center of Benghazi (Libya). The IDF and AHA/NHLBI definitions were used to diagnose metabolic syndrome among 136 patients. Blood samples were taken following a 12-hour fast, and clinical data was documented. All biochemical parameters were assessed in the biochemistry laboratory of Benghazi Cardiovascular Center using standard protocols. Out of the 136 subjects, 77.2% of patients were found to have metabolic syndrome, and it was more common in males than females. The mean age, blood pressure (BP), fast blood glucose (FBG), and high density lipoprotein (HDL-C) levels were significantly associated with the presence of Mets. Compared to CVD patients without Mets, central obesity (72.1%; P=0.003) and high FBG (69.1%; P=0.000) were significantly the main prevalent components of Mets. High DBP and high SBP presented a significant association with age group and were found to be more prevalent among the age group between 50 and 60 years and the group of patients aged more than 60 years (> 60 years), respectively. Libyan patients with CVDs express a high incidence of metabolic syndrome. Central obesity and high FBG were the main prevalent components of Mets. High BP was found to be associated with aging in Mets patients. Early diagnosis and management of these CVD risk factors seems to be necessary and crucial to prevent subsequent complications.

VIEWS 49
Cover PDF

Abourazzak F, Talbi S, Lazrak F, Azzouzi H, Aradoini N, Keita S, Errasfa M, Harzy T. 2015. Does metabolic syndrome or its individual components affect pain and function in knee osteoarthritis women? Current Rheumatology Review 11, 8–14.

Adejumo EN, Adejumo AO, Azenabor A, Ekun AO, Enitan SS, Adebola OK, Ogundahunsi OA. 2019. Anthropometric parameter that best predicts metabolic syndrome in South West Nigeria. Diabetes and Metabolic Syndrome 3(1), 48–54.

Alberti KG, Zimmet P, Shaw J, IDF Epidemiology Task Force Consensus Group. 2005. The metabolic syndrome- A new worldwide definition. Lancet 366(9491), 1059–62.

Alshkri M, Elmehdawi R. 2007. Metabolic syndrome among type-2 diabetic patients in Benghazi-Libya: A pilot study. Libyan Journal of Medicine 3(4), 177–180.

Annani-Akollor ME, Laing EF, Addai-Mensah O, Fondjo LA, Adu EA, Owiredu EW. 2020. Population-derived cut-off for HbA1c could enhance the identification of metabolic syndrome among non-diabetic population. Heliyon 6(8), e04583.

Ben Ali S, Belfki-Benali H, Aounallah-Skhiri H, Traissac P, Maire B, Delpeuch F, Achour N, Ben Romdhane H. 2014. Menopause and metabolic syndrome in Tunisian women. Biomed Research International 2014, 457131.

Bertoni AG, Bonds DE, Steffes S, Jackson E, Crago L, Balasubramanyam A, Chen H, Goff DC Jr. 2006. Quality of cholesterol screening and management with respect to the National Cholesterol Education’s Third Adult Treatment Panel (ATPIII) guideline in primary care practices in North Carolina. American Heart Journal 152(4), 785–92.

Bollyky TJ, Templin T, Cohen M, Dieleman JL. 2017. Lower-income countries that face the most rapid shift in noncommunicable disease burden are also the least prepared. Health Affairs (Millwood) 36(11), 1866–1875.

Bowo-Ngandji A, Kenmoe S, Ebogo-Belobo JT, Kenfack-Momo R, Takuissu GR, Kengne-Ndé C, Mbaga DS, Tchatchouang S, Kenfack-Zanguim J, Lontuo Fogang R, Zeuko’o Menkem E, Ndzie Ondigui JL, Kame-Ngasse GI, Magoudjou-Pekam JN, Wandji Nguedjo M, Assam Assam JP, Enyegue Mandob D, Ngondi JL. 2023. Prevalence of the metabolic syndrome in African populations: A systematic review and meta-analysis. PLoS One 18(7), e0289155.

Després JP, Lemieux I, Bergeron J, Pibarot P, Mathieu P, Larose E, Rodés-Cabau J, Bertrand OF, Poirier P. 2008. Abdominal obesity and the metabolic syndrome: contribution to global cardiometabolic risk. Arteriosclerosis Thrombosis and Vascular Biology 28(6), 1039–49.

GBD 2019 Risk Factors Collaborators. 2020. Global burden of 87 risk factors in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet 396(10258), 1223–49.

Huang Y, Ao Y, Wan X, Liu X, Yao J, Ye H, Wang A, Zhuang P, Jiao J, Zhang Y. 2024. Assessing the hypertension risk: a deep dive into cereal consumption and cooking methods-insights from China. Nutrients 16(17), 3027.

Intapad S, Tull FL, Brown AD, Dasinger JH, Ojeda NB, Fahling JM, Alexander BT. 2013. Renal denervation abolishes the age-dependent increase in blood pressure in female intrauterine growth-restricted rats at 12 months of age. Hypertension 61(4), 828–34.

Jahangiry L, Farhangi MA, Rezaei F. 2017. Framingham risk score for estimation of 10-years of cardiovascular diseases risk in patients with metabolic syndrome. Journal of Health Population and Nutrition 36(1), 36.

Julibert A, Bibiloni MDM, Bouzas C, Martínez-González MÁ, Salas-Salvadó J, Corella D, Zomeño MD, Romaguera D, Vioque J, Alonso-Gómez ÁM, Wärnberg J, Martínez JA, Serra-Majem L, Estruch R, Tinahones FJ, Lapetra J, Pintó X, Lopez-Miranda J, García-Molina L, Gaforio JJ, Matía-Martín P, Daimiel L, Martín-Sánchez V, Vidal J, Vázquez C, Ros E, Toledo E, Becerra-Tomás N, Pórtoles O, Pérez-Vega KA, Fiol M, Torres-Collado L, Tojal-Sierra L, Carabaño-Moral R, Abete I, Sanchez-Villegas A, Casas R, Bernal-López MR, Santos-Lozano JM, Galera A, Ugarriza L, Ruiz-Canela M, Babio N, Coltell O, Schröder H, Konieczna J, Orozco-Beltrán D, Sorto-Sánchez C, Eguaras S, Barrubés L, Fitó M, Tur JA; Predimed-Plus Investigators. 2019. Total and subtypes of dietary fat intake and its association with components of the metabolic syndrome in a Mediterranean population at high cardiovascular risk. Nutrients 11(7), 1493.

Reaven GM. 1988. Banting lecture: role of insulin resistance in human disease. Diabetes 37(12), 1595–607.

Regitz-Zagrosek V, Lehmkuhl E, Mahmoodzadeh S. 2007. Gender aspects of the role of the metabolic syndrome as a risk factor for cardiovascular disease. Gender Medicine 4S, 162–77.

Saely CH, Koch L, Schmid F, Marte T, Aczel S, Langer P, Hoefle G, Drexel H. 2006. Adult Treatment Panel III 2001 but not International Diabetes Federation 2005 criteria of the metabolic syndrome predict clinical cardiovascular events in subjects who underwent coronary angiography. Diabetes Care 29(4), 901–7.

Safar ME, Thomas F, Blacher J, Nzietchueng R, Bureau JM, Pannier B, Benetos A. 2006. Metabolic syndrome and age-related progression of aortic stiffness. Journal of the American College of Cardiology 47(1), 72–5.

Salari N, Doulatyari PK, Daneshkhah A, Vaisi-Raygani A, Jalali R, Jamshidi PK, Abdi A, Mohammadi M, Kazeminia M. 2020. The prevalence of metabolic syndrome in cardiovascular patients in Iran: a systematic review and meta-analysis. Diabetology and Metabolic Syndrome 12(1), 96.

Santos AC, Severo M, Barros H. 2010. Incidence and risk factors for the metabolic syndrome in an urban South European population. Preventive Medicine 50(3), 99–105.

Shahabi N, Rafati S, Kakhaki HES, Soleimani F, Zamaninasab F, Saboohi Z, Nejatizadeh A, Dadipoor S. 2024. Assessing the risk of metabolic syndrome and diabetes in relation to hookah smoking: evidence from a cohort study in Southern Iran. Health Science Reports 7(4), e1996.

Sowers JR. 2013. Diabetes mellitus and vascular disease. Hypertension 61(5), 943–7.

Visseren FLJ, Mach F, Smulders YM, Carballo D, Koskinas KC, Bäck M, Benetos A, Biffi A, Boavida JM, Capodanno D, Cosyns B, Crawford C, Davos CH, Desormais I, Di Angelantonio E, Franco OH, Halvorsen S, Hobbs FDR, Hollander M, Jankowska EA, Michal M, Sacco S, Sattar N, Tokgozoglu L, Tonstad S, Tsioufis KP, van Dis I, van Gelder IC, Wanner C, Williams B; ESC National Cardiac Societies; ESC Scientific Document Group. 2021. 2021 ESC Guidelines on cardiovascular disease prevention in clinical practice. European Heart Journal 42(34), 3227–37.

Wang H, Liu J, Feng Y, Ma A, Wang T. 2023. The burden of cardiovascular diseases attributable to metabolic risk factors and its change from 1990 to 2019: a systematic analysis and prediction. Frontiers in Epidemiology 3, 1048515.

World Health Organisation. 2011. Waist circumference and waist-hip ratio report of a WHO expert consultation, Geneva.

Zimmet P, Alberti KG, Serrano Ríos M. 2005. A new International Diabetes Federation worldwide definition of the metabolic syndrome: the rationale and the results. Revista Espagnola de Cardiologia 58(12), 1371–6.

Submit Manuscript