Prevalence of Pulmonary Tuberculosis: A Two Years Retrospective Study in the Northern Area of KP, Pakistan

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Research Paper 28/07/2022
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Prevalence of Pulmonary Tuberculosis: A Two Years Retrospective Study in the Northern Area of KP, Pakistan

Wajid Hussain, Numan Salehzada, Alam Zeb Khan, Mati Ullah
Int. J. Biosci.21( 1), 56-63, July 2022.
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Tuberculosis (TB), an airborne infectious disease caused by Mycobacterium tuberculosis, accounts for considerable morbidity and mortality worldwide. The current study provides an estimate of the prevalence of the bacteriologically positive pulmonary tuberculosis (PTB) population in the northern area of KPK, Pakistan. A cross-sectional study was designed for the suspected population of PTB and all the individuals were interviewed for symptoms suggestive of PTB diseases. Two sputum specimens were collected from all eligible individuals and were examined by Ziehl-Neelsen smear microscopy. A total of 959 and 820 eligible individual samples were collected in the year 2016 and 2017 (January to December), respectively. In the year 2016, 91 individuals were bacteriologically positive and the prevalence of PTB was found at 9.48 % (n-91) (45 % were male and 55 % were female). Similarly, in the year 2017, 52 individuals were bacteriologically positive and the prevalence of PTB was found at 6.34 % (48% were male and 52% were female). The highest prevalence of PTB was found within the age group 21-40 years 25.4% (n-45) (51.1% were male and 48.8% were female) and 42.3% (n-22) (54.5% were male and 45.4% were female) in the year 2016 and 2017 respectively. The highest infection rate in this group might be due in terms of their jobs and regular interaction with society. However, early diagnosis is crucial to prevent the multi-drug resistance cases of PTB and further strengthen the TB control program.


Agboatwalla M, Kazi G, Shah S, Tariq M. 2003. Gender perspectives on knowledge and practices regarding tuberculosis in urban and rural areas in Pakistan.

Ahmad T, Jadoon MA, Haroon, Khattak MNK. 2016. Prevalence of sputum smear positive pulmonary tuberculosis at Dargai, District Malakand, Pakistan: A four year retrospective study. Egyptian Journal of Chest Diseases and Tuberculosis 65, 461-464.

Akhtar N, Khan BT, Khan J, Saeed K, Khan S, Ahmad Z. 2014. Prevalence of Tuberculosis: Current Status in Manglawar District Swat, Khyber Pakhtunkhwa, Pakistan. European Academic Research 1, 5160-5166.

Ayaz S, Nosheen T, Khan S, Khan SN, Rubab L, Akhtar MJT. 2012. Pulmonary tuberculosis: still prevalent in human in Peshawar, Khyber Pakhtunkhwa, Pakistan. Tuberculosis 10, 39-41.

Bhat J, Rao VG, Gopi PG, Yadav R, Selvakumar N, Tiwari B, Gadge, V, Bhondeley MK, Wares F. 2009. Prevalence of pulmonary tuberculosis amongst the tribal population of Madhya Pradesh, central India. International journal of epidemiology, dyp222.

Ejaz M, Siddiqui, AR, Rafiq Y, Malik F, Channa A, Mangi R, Habib F, Hasan R. 2010. Prevalence of multi-drug resistant tuberculosis in Karachi, Pakistan: identification of at risk groups. Transactions of the Royal Society of Tropical Medicine and Hygiene 104, 511-517.

Holmes C, Hausler H, Nunn P. 1998. A review of sex differences in the epidemiology of tuberculosis. The International Journal of Tuberculosis and Lung Disease 2, 96-104.

Khan N, Mehmood SA, Shah M, Ahmad S, Mahmood S, ALI M. 2015. Prevalance of tuberculosis in District Dir Upper, Pakistan. Global Advanced Research Journal of Microbiology.

Maher D, Raviglione M. 2005. Global epidemiology of tuberculosis. Clinics in chest medicine 26, 167-182.

Meyers WM, Walsh DS, Portaels F. 2011. Mycobacterium ulcerans Infection (Buruli Ulcer). Tropical Infectious Diseases: Principles, Pathogens and Practice. Edinburgh: W.B. Saunders.

Negin J, Abimbola S, Marais BJ. 2015. Tuberculosis among older adults–time to take notice. International Journal of Infectious Diseases 32, 135-137.

Onyango RO. 2011. State of the globe: Tracking tuberculosis is the test of time. Journal of global infectious diseases 3, 1.

Organization WH. 2013. Global tuberculosis report 2013, World Health Organization.

Qadeer E, Fatima R, Yaqoob A, Tahseen S, Haq MU, Ghafoor A, Asif M, Straetemans M, Tiemersma EW. 2016a. Population based national tuberculosis prevalence survey among adults (> 15 years) in Pakistan, 2010–2011. PloS one 11, e0148293.

Qadeer E, Fatima R, Yaqoob A, Tahseen S, UL Haq M, Ghafoor A, Asif M, Straetemans M, Tiemersma EW. 2016b. Population Based National Tuberculosis Prevalence Survey among Adults (>15 Years) in Pakistan, 2010-2011. PLoS One 11, e0148293.

Saleem M, Ahmad W, Jamshed F, Sarwar J, Gul N. 2013. Prevalence of tuberculosis in Kotli, Azad Kashmir. J Ayub Med Coll Abbottabad 25, 175-8.

Vermund SH, Altaf A, Samo RN, Khanani R, Baloch N, Qadeer E, Shah SA. 2009. Tuberculosis in Pakistan: A decade of progress, a future of challenge. Journal of Pakistan Medical Association 59, 1-8.

Zaman M. 2010. Frequency of Sputum Positive AFB cases among patients of Pulmonary Tuberculosis in Tertiary care hospitals of Northern Pakistan. J Ayub Med Coll Abbottabad, 22.

Zignol M, Gemert WV, Falzon D, Sismanidis C, Glaziou P, Floyd K. Raviglione M. 2012. Surveillance of anti-tuberculosis drug resistance in the world: an updated analysis, 2007-2010. Bulletin of the world Health Organization 90, 111-119.

Zuml AA, George A, Sharma V, Herbert RHN, Oxley A, Oliver M. 2015. The WHO 2014 global tuberculosis report-further to go. J The Lancet Global Health 3, e10-e12.