Risk factors, genetic mutations and prevention of breast cancer

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Review Paper 01/04/2019
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Risk factors, genetic mutations and prevention of breast cancer

Muhammad Naeem, Muhammad Hayat, Sarmad Ahmad Qamar, Tariq Mehmood, Ahmad Munir, Ghafoor Ahmad, Umair Rasool Azmi, Muhammad Adeel Faryad, Muhammad Zeeshan Talib, Muhammad Irfan, Asim Hussain, Muhammad Awais Hayder, Usman Ghani, Faisal Mehmood
Int. J. Biosci.14( 4), 480-484, April 2019.
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Breast cancer is the second leading cause of cancer deaths among women. The breast is generally common site of noncutaneous cancer among women. Numerous genetic and clinical factors are involved in increasing the risk of developing breast cancer among women. This review focused on pathogenesis, related genes, risk factors and preventive methods that implement on the breast cancer over past years strategies in present use to stop breast cancer, as well as prospective approach that could be used in future. A set of somatic alterations as well as mutations and also gene amplifications are involved in etiology of various forms of breast cancer. Diagnosis of breast cancer at the Initial stages is one of the most excellent approaches to prevent this disease. Presently, people have supplementary drug option for the chemoprevention of breast cancer, while prevention using biological methods has been in recent times developed to recover quality of life of patients suffering from breast cancer. In addition, prevention clinical trials are starting to estimate multi agent cancer prevention approach with the expectation of improved effectiveness over single agents.


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