Seminal plasma proteins and buffalo bull’s fertility

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Review Paper 01/04/2018
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Seminal plasma proteins and buffalo bull’s fertility

Nagina Gilani, Hasina Basharat, Shamim Akhter
Int. J. Biosci.12( 4), 267-272, April 2018.
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Seminal plasma is the acellular part of the semen with composition varying among different species due to the difference in glands or type of ejaculate they have. It is basically composed of seminal plasma proteins which perform many functions, but most of them have not been studied in detail, especially the functions related to fertility regulation and fertilization. Bull fertility is an important aspect of fertilization affected by seminal plasma proteins. The present review attempts to review composition of seminal plasma of mammals, its major proteins and their functions regarding sperm function with a particular focus on its role in fertility indication in bull. Different studies on seminal plasma proteomics, beneficial as well as the harmful role of seminal plasma proteins on sperm function and fertility regulation was investigated. Most important proteins working as bull fertility markers are the osteopontin, prostaglandins D synthase and sperm adhesion 2. Of these higher amounts of osteopontin are found in bulls of higher fertility and higher amounts of sperm adhesion 2 are found in bulls of lower fertility. From these studies it is clear that seminal plasma proteins are necessary for both spermatozoa and oocytes functionality and therefore play an important role in bulls fertility as well as infertility.


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