Seminal plasma proteins and buffalo bull’s fertility

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Review Paper 01/04/2018
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Seminal plasma proteins and buffalo bull’s fertility

Nagina Gilani, Hasina Basharat, Shamim Akhter
Int. J. Biosci.12( 4), 267-272, April 2018.
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Abstract

Seminal plasma is the acellular part of the semen with composition varying among different species due to the difference in glands or type of ejaculate they have. It is basically composed of seminal plasma proteins which perform many functions, but most of them have not been studied in detail, especially the functions related to fertility regulation and fertilization. Bull fertility is an important aspect of fertilization affected by seminal plasma proteins. The present review attempts to review composition of seminal plasma of mammals, its major proteins and their functions regarding sperm function with a particular focus on its role in fertility indication in bull. Different studies on seminal plasma proteomics, beneficial as well as the harmful role of seminal plasma proteins on sperm function and fertility regulation was investigated. Most important proteins working as bull fertility markers are the osteopontin, prostaglandins D synthase and sperm adhesion 2. Of these higher amounts of osteopontin are found in bulls of higher fertility and higher amounts of sperm adhesion 2 are found in bulls of lower fertility. From these studies it is clear that seminal plasma proteins are necessary for both spermatozoa and oocytes functionality and therefore play an important role in bulls fertility as well as infertility.

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Avila FW, Sirot IK, Laflamme BA, Rubinstein CD, Wolfner MF. 2011. Insect seminal fluid proteins: identification and function. Annual Review of Entomology 56, 21-40. http://dx.doi.org/10.1146/annurev-ento-120709-144823.

Bellin ME, Oyarzo JN, Hawkins HE, Zang HM, Smith RG, Forest DW, Sprot IR, Ax RL. 1998.Fertility associated antigen of bull sperm indicates fertility potential. Journal of Animal Science 76(8), 2032-2039.

Beyler SA, Zaneveld LJD. 1982. Inhibition of in vitro fertilization of mouse gametes by proteinase (acrosin) inhibitors Journal of Reproduction and Fertility 66, 425-31.

Bjorndahl L, Kvist U.2010.Human sperm chromatin stabilization: a proposed model including zinc bridges. Molecular Human Reproduction 16, 23-29. http://dx.doi.org/10.1093/molehr/gap099.

Brown IF, Berse B, Van DWL, Papadopoulos SA, Perruzzi CA, Manseau EJ, Dvorak HF, Senger DR. 1992. Expression and distribution of osteopontin in human tissues: widespread association with luminal epithelial surfaces. Molecular biology of cell 3, 1169–1180.

Burden HP, Holmes CH, Persad R, Whittington K. 2006. Prostasomes and their effects on human male reproduction and fertility. Human Reproduction Update 12,283-292. https://doi.org/10.1093/humupd/dmi052

Caballero I, Vazquez JM, Garcia EM, Parrilla I, Roca J, Calvete JJ, Sanz I, Martinez EA. 2008. Major proteins of boar seminal plasma as a tool for biotechnological preservation of spermatozoa. Theriogenology 70,1352-1355. http://dx.doi.org/10.1016/j.theriogenology.2008.07.013.

Calvete JJ, Sanz I. 2007.Insights into structure-function correlations of ungulate seminal plasma proteins. Society of Reproduction Fertility and Supplements 65, 201-215.

Cancel AM, Chapman DA, Killian GJ. 1997. Osteopontin is the 55-kilodalton fertility-associated protein in Holstein bull seminal plasma. Biology of Reproduction57(6), 1293-1301.

Cancel AM, Chapman DA, Killian GJ. 1999. Osteopontin localization in the Holstein bull reproductive tract. Biology of Reproduction 60, 454-460. https://doi.org/10.1095/biolreprod60.2.454.

ChacurMGM.2011.Season influence upon seminal plasma proteins in Brown-Swiss bulls. Archive Zootech 60, 301-304.

Drake RR, Elschenbroich A, Lopez PO, Kim Y, Ignatchenko V, Ignatchenko A, Nyalwidhe JO, Basu G, Wilkins CE, Gjurich B, Lance RS, Semmes OJ, Medin JA, Kislinger T. 2010.In-depth proteomic analyses of direct expressed prostatic secretions. Journal of Proteomics Research 9, 2109-2116. http://dx.doi.org/10.1021/pr1001498.

Duncan MW, Thompson HS. 2007. Proteomics of semen and its constituents. Proteomics Clinical Applications 1,861-875.

Ekhlasi HM, Schafer B, Kirchhoff C, Hess O, Bellair S, Muller P, Topfer PE. 2005. Structural and molecular characterization of equine sperm-binding fibronectin-II module proteins. Molecular Reproduction 70,45-57.

Gerena RL, Irikura D, Eguchi N, Urade Y, Killian GJ. 2000. Immunocyto-chemical localization of lipocalin type prostaglandin D synthase in bull testis and epididymis and on ejaculated sperm. Biology of Reproduction 62(3), 547-556.

Greube A, Muller K, Topfer PE, Herrmann A, Muller P. 2004. Interaction of fibronectin type II proteins with membranes: the stallion seminal plasma protein SP-1/2. Biochemistry 43,464-472.

Iwamoto T, Tanaka H, Osada T, Shinagawa T, Osamura Y, Gagnon C. 1993.Origin of a sperm motility inhibitor from boar seminal plasma. Molecular Reproduction and Development 36, 475–481.

Jobim MIM, Oberst ER, Salbego CG, Wald VB, Horn AP, Mattosr C.2005.BSP A1/A2-like proteins in ram seminal plasma. Theriogenology 63(7), 2053-2062.

Kelly VC, Kuy S, Palmer DJ, Xu Z, Davis SR, Cooper GJ. 2006. Characterization of bovine seminal plasma by proteomics. Proteomics 6,5826-5833.

KoubovaJ,Menke DB, Zhou Q, Capel B, Griswold MD, Page DC. 2006. Retinoic acid regulates sex specific timing of meiotic initiation in mice. Proceedings of the National Academy of Sciences of the United States of America103, 2474-2479.

Kumar P, Kumar D, Singh I, Yadav P. 2012. Seminal Plasma Proteome: Promising Biomarkers for Bull Fertility. Agricultural research 1(1),78-86.

Liberda J, Ticha M, Zraly Z, Svecova D, Veznik 1998. Interaction of bull, stallion and boar seminal plasma proteins and sperms with acidic polysaccharides. Folia Biologia 44,177-183.

Manaskova P,Jkanova V.2008.Localization of porcine seminal plasma (PSP) proteins in the boar reproductive tract and spermatozoa. Journal of Reproduction and Immunology 78, 40-48.

Manjunath P, Bergeron A, Lefebvre J, Ton J. 2008. Seminal plasma proteins: Function and interaction with protective agents during semen preservation. Biochemistry Biophysics Acta 1784, 891-899.

Mccauley TM, Zhang HM, Bellin ME, AxRL. 1999. Purification and characterization of fertility-associated antigen (FAA) in bovine seminal fluid. Molecular Reproduction and Development 54, 145-153.

Mccauley TC, Zhang HM, Bellin ME, Ax RL. 2001.Identification of heparin binding protein in bovine seminal fluid as tissue inhibitor metalloproteinases-2. Molecular Reproduction and Development 58, 336-341.

Milardi D,Grande G, Vincenzoni F, Messana I, Pontecorvi AA, Marinis ID, Castagnola M, Marana R. 2012. Proteomic approach in the identification of fertility pattern in seminal plasma offertile men. Fertility and Sterility 97,67-73.

Moldenhauer IM, Diener KR, Thring DM, Brown MP, Hayballn JD, Robertson JA. 2009. Cross presentation of male seminal fluid antigens elicits T-cell activation to initiate the female immune response to pregnancy. Journal of Immunology 182, 8080–8093.

Moura AA, Chapman DA, Koc H, Killian GJ. 2006. Proteins of the cauda epididymal fluid associated with fertility of mature dairy bulls. Journal of Andrology 27, 534–541.

Moura AA, Chapman DA, Koc H, Killian GJ. 2007. A comprehensive proteomic analysis of the accessory sex gland fluid from mature Holstein bulls. Animal Reproduction Science 98, 169-188.

Nauc V, Manjunath P. 2000. Radioimmunoassay for bull seminal plasma proteins (BSP-A1/-A2, BSP-A3, and BSP-30-kilodaltons), and their quantification in seminal plasma and sperm. Biology of Reproduction 63,1058–1066.

Novak S, Ruiz SA, Dixon WT, Foxcroft GR, Dyck MK. 2010. Seminal plasma proteins as potential markers of relative fertilityin boars. Journal of Andrology 31,188–200. http://dx.doi.org/10.2164/jandrol.109.007583.

Rodriguez MH, Kvist U, Saravia F, Wallgren M, Johannisson A, Sanz I, Pena FJ, Martinez J, Roca EA, Vazquez JM, Calvete JJ. 2009. The physiological roles of the boar ejaculate. In: “Control of Pig Reproduction VIII” eds H Rodriguez-Martinez, JL Vallet, AJ Ziecik. Nottingham University Press, UK, p. 1-21.

Rodriguez MH, Saravia F, Wallgren M, Martinez EA, SanzI, Roca J, Vazquez JM, Calvete JJ. 2010.Sperm-adhesin PSP-I/PSP-II heterodimer induces migration of poly-morpho-nuclear neutrophils into uterine cavity of the sow. Journal of Reproductive Immunology 84, 57-65.

Topfer PE, Ekhlasi HM, Kirchhoff C, Leeb T, Sieme H. 2005. The role of stallion seminal plasma proteins in fertilization. Animal Reproduction Science 89,159-170.

Topfer PE, Ekhlasi HM, Tsolova M. 2008. Glyco-biology of fertilization in the pig. International Journal of Developmental Biology 52,717-736.

Vadnais ML, Roberts KP. 2010.Seminal plasma proteins inhibit in vitro- and cooling-induced capacitation in boar spermatozoa. Reproduction Fertility and Development 22,893-900. https://doi.org/10.1071/RD09274

Varilova T, Semenkova H, Horak P, Madera M, Pacakova V, Ticha M, Stulik K.2006.Affinity liquid chromatography and capillary electrophoresis of seminal plasma proteins.Journal of Separation Science p.29.

Villemure M, Lazure C, Manjunath P. 2003. Isolation and characterization of gelatin-binding proteins from goat seminal plasma. Reproduction Biology and Endocrinology 1,39. http://dx.doi.org/10.1186/1477-7827-1-39

WATSON PF. 1995. Recent development and concepts in the cryopreservation of spermatozoa and the assessment of their post-thawing function. Reproduction Fertility and Development7, 871-891.

WHO. 2010.Laboratory Manual for the Examination and Processing of Human Semen. Cambridge: WHO Press, 5th edition, p. 271.

Zhang BR, Larsson B, Lundeheim N. Rodriguez MH. 1998. Sperm characteristics and zona pellucida binding in relation to filed fertility of frozen thawed semen from dairy AI bulls. International Journal of Andrology 21, 207- 216.