Sero-epidemiology of human Toxoplasma gondii infection among male population in Charsadda, KPK, Pakistan

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Research Paper 01/04/2018
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Sero-epidemiology of human Toxoplasma gondii infection among male population in Charsadda, KPK, Pakistan

HasnainJan, Muhammad Haroon, Shah Faisal, Abid Kamal, Muhammad Taimur Khan, Kainat Ahmad, Wali Muhammad
Int. J. Biosci. 12(4), 110-116, April 2018.
Copyright Statement: Copyright 2018; The Author(s).
License: CC BY-NC 4.0

Abstract

Toxoplasmosis is a zoonotic infection of humans and animals which is caused by the opportunistic protozoan Toxoplasma gondii. The parasite belongs to the phylum Apicomplexa. Worldwide one-third of the total population are chronically infected by the parasite. Clinically the parasitic infection produces a wide range of symptoms in the humans. The deteriorating health impact includes blindness and mental retardation in congenitally infected children. The aim of the current study was to determine the seroprevalence of T. gondii among male population in District Charsadda, KPK. 300 random samples were collected from the male population. Serum was extracted from the samples and was subjected to the serological technique. The detection was done with Latex Agglutination kit. Out of 300 samples, 63 (21%) were found positive for the parasite. A significant association was determined between the infection and age group in the population. From results, it was concluded that the infection was more prevalent in the age group 46-55 years with 35.41% followed by the age groups 66-75 years, 56-65 years, 36-45 years, 26-35 years and 15-25 years with 33.33%, 30.55%, 22.95%, 18.46% and 8.33% respectively. Bringing awareness to the public and educate them about the health-associated risks upsurging from unhealthy food and lifestyle habits. In the future updates of the global burden of infections, the data on Toxoplasmosis epidemiology and its transmission should be included in order to support public health interferences to eradicate the disease burden.

Ades A, ParkerS, Gilbert R, Tookey P, Berry T, Hjelm M, WilcoxA, Cubitt D, PeckhamC. 1993. “Maternal prevalence of Toxoplasma antibody based on anonymous neonatal serosurvey: a geographical analysis.” Epidemiology & Infection 110(1),127-133.

Al-Saadii, S. H. M. (2013). The effect of toxoplasmosis on the level of some male sex hormones In Samples from National Blood Transfusion Center/Baghdad, M. Sc. Thesis. College of Science. University of Baghdad.

Ally SH, Idris M. 2004. “Frequency of antitoxoplasma antibodies in patients with ocular pathology.” J Ayub Med Coll Abbottabad 16(4), 75-76.

Arshad M, Cheema K, Malik H, Sajjad S. 2017. “THE PROBABLE RELATION BETWEEN TOXOPLASMA GONDII AND DIABETES MELLITUS.” Pakistan Journal of Science 69(2).

Ashburn D. 1992. “History and general epidemiology.” Human toxoplasmosis. Ho-Yen DO, Joss AWL, eds. Oxford: Oxford Medical Publications: 1-25.

Chintapalli S, Padmaja IJ. 2013. “Seroprevalence of toxoplasmosis in antenatal women with bad obstetric history.” Tropical parasitology 3(1), 62.

Derouin F, Pelloux H. 2008. “Prevention of toxoplasmosis in transplant patients.” Clinical Microbiology and Infection 14(12), 1089-1101.

Flegr J, Prandota J, Sovičková M, Israili ZH. 2014. “Toxoplasmosis–a global threat. Correlation of latent toxoplasmosis with specific disease burden in a set of 88 countries.” PloS one 9(3),e90203.

Hayat S, Tasawar Z, Akhtar T. 2014. “Seroprevalence of human toxoplasmosis in Kallarwali village of district Muzaffar Garh, Pakistan.” Gomal Journal of Medical Sciences 12(3), 129.

Hedqvist T. 1953. “Toxoplasma infection at different ages, studied by the skin-test method.” Epidemiology & Infection 51(4), 478-482.

Jones JL, Kruszon-Moran D, Wilson M, McQuillan G, Navin T, McAuley JB.2001. “Toxoplasma gondii infection in the United States: seroprevalence and risk factors.” American journal of epidemiology 154(4), 357-365.

LEVINE ND. 1977. “Taxonomy of Toxoplasma.” Journal of Eukaryotic Microbiology 24(1), 36-41.

Majumdar D. 2010. “Study of Population Diversity of Toxoplasma gondii.”

Sadaruddin A, Agha F, Anwar F, GhafoorA. 1991. “Seroepidemiology of Toxoplasma gondii infection in young school children in Islamabad.” J Pak Med Assoc 41(6),131-134.

Shah M, Zahid M, Bibi B, Hussain A, Haroon M, Ali B. 2017. “Chromatographic immunoassay based detection of human toxoplasmosis in District Mardan, Khyber Pakhtunkhawa, Pakistan.” Pure and Applied Biology (PAB) 6(4), 1297-1305.

Sousa OE, Saenz RE, Frenkel JK. 1988. “Toxoplasmosis in Panama: a 10-year study.” The American journal of tropical medicine and hygiene 38(2), 315-322.

Studeničová C, Benčaiová G, Holková R.2006. “Seroprevalence of Toxoplasma gondii antibodies in a healthy population from Slovakia.” European journal of internal medicine 17(7), 470-473.

Tasawar Z, Aziz F, Lashari MH, Shafi S, Ahmad M, Lal V, Hayat CS. 2012. “Seroprevalence of Human toxoplasmosis in southern Punjab, Pakistan.” Pak J Life Soc Sci 10, 48-52.

Tenter AM, Heckeroth AR, Weiss LM.  2000. “Toxoplasma gondii: from animals to humans.” International journal for parasitology 30(12),1217-1258.

Zeipel GV, Linder L. 1951. “Toxoplasmosis a serological investigation with dye test.” APMIS 29(3), 229-238.

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