Seroepidemiology of Toxoplasma gondii infection among human population in Lahore
Paper Details
Seroepidemiology of Toxoplasma gondii infection among human population in Lahore
Abstract
Toxoplasmosis is a zoonotic disease caused by Toxoplasma gondii with worldwide distribution causing infection in humans and warm blooded animals. The present study deals with the detection of Toxoplasma infection among humans, because in Pakistan majority of the work done about T. gondii infection is related to domestic animals. Questionnaire survey was administered to identify transmission risk factors for T. gondii among study population. ELISA was used to determine Toxoplasma antibodies (IgG and IgM) in serum samples (n=360) of study respondents. Results were analyzed statistically by using Chi-square test (p<0.05). Overall seroprevalence of Toxoplasma infection among respondents was 60%. It was found that chronic Toxoplasma infection was more prevalent (58.5%) as compared to acute one (41.5%). Gender-wise comparison showed that prevalence of infection was higher among males (86%) as compared to females (34%). It was noted that chronic toxoplasmosis was more prevalent in male population suggesting long exposure of males to contaminated surfaces as compared to females. Seroprevalence of Toxoplasma was found to be associated with age of respondents. It was observed that for both male and female respondents the higher Toxoplasma infection was in subjects of 36-44 years of age that indicated positive association of Toxoplasma infection with age. It was concluded that Toxoplasma infection was highly prevalent in study population and was associated with age, low socioeconomic status and pica habits. Current findings demand multidisciplinary studies regarding susceptible groups to find out relationship of toxoplasmosis and associated risk factors for prevention and management of public health.
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Mateen Arshad, Kausar Jamal Cheema, Husna Jabeen Malik, Sumera Sajjad, 2017. Seroepidemiology of Toxoplasma gondii infection among human population in Lahore. Int. J. Biosci., 10(3), 192-198.
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