Int. J. Biosci.2( 8), 115-119, August 2012
Accumulating evidence indicates that obesity and overweight are associated with chronic low grade inflammation. The aim of our work was to study the effect aerobic exercise training on glycosylated hemoglobin and acute phase C-reactive protein (CRP) in diabetic patients. Thirty-eight sedentary, nonsmoking, type II diabetic (BMI: 30–35 kg/m2) men, aged 38–46 years, were recruited to participate to study and divided in to exercise (3 months, 3 sessions/weekly) and control (no training) group by randomly. Pre and post training CRP, glycosylated hemoglobin and anthropometrical parameters were measured in exercise and control groups and compared with each other. Aerobic exercise training resulted in significant decrease in body weight, body mass index and body fat percentage in exercise group (p<0.05). Glycosylated hemoglobin levels were significantly decreased in response to exercise training when compared with baseline levels (p=0.033). But, serum CRP did not change with aerobic exercise training. All variables in control group remained without changes. We conclude that there are no meaningful chronic effects of exercise on serum CRP, even in presence a improving in glycosylated hemoglobin in diabetic patients.
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