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Serum interleukin -1 beta in relation to cardiorespiratory fitness and anthropometry on obese and overweight women

Alinoori Fariba, Maryam Husseini Shakib, Leila Husseini

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J. Bio. Env. Sci.5(1), 664-669, July 2014


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Epidemiologic studies clearly show that obesity and sedentary is associated with low physical fitness. The purpose of this study was to analyze whether cardiorespiratory fitness (CRF) and obesity determinants are associated with serum IL-1ß as inflammatory cytokine in women with obesity or overweight. For this purpose, forty sedentary healthy overweight/obese women, 38 ± 4.2 year-olds were participated in this study by accessible sampling. Serum IL-1ß was measured after an overnight fast. Anthropometry, resting and submaximal heart rate and maximal oxygen consumption (VO2max) were measured by standard cycling test. Pearson correlation coefficients were used to determine the associations between VO2max with other variables. A p-value less than 0.05 were considered statistically significant. Analysis data showed no significant correlation in VO2max with all anthropometrical markers. Serum IL-1ß was not correlated with VO2max, anthropometrical markers, resting and submaximal heart rate. Based on these data, it’s concluded that cardiorespiratory fitness is not directly correlated with inflammation in obese or overweight women. Further studies are necessary to elucidate mechanisms underlying by which inflammation affect physical fitness in this population.


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Serum interleukin -1 beta in relation to cardiorespiratory fitness and anthropometry on obese and overweight women

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