Studies on genetic diversity of kongu vellalar population using mitochondrial DNA and Y- chromosome markers

Paper Details

Research Paper 01/06/2012
Views (1846)
current_issue_feature_image
publication_file

Studies on genetic diversity of kongu vellalar population using mitochondrial DNA and Y- chromosome markers

K. Sabariswaran, A. Rajesh, R. Indumathi, K.Thangaraj, V.G. Abilash5
Int. J. Biosci. 2(6), 72-81, June 2012.
Copyright Statement: Copyright 2012; The Author(s).
License: CC BY-NC 4.0

Abstract

The genetic diversity of Kongu Vellalar population of Salem District Tamil Nadu was studied using mt DNA and Y-chromosomal biallelic SNP markers.In this study, 400 base pair of the HVR-1 region and selected coding regions of the mitochondrial DNA (mtDNA), and 8 Y chromosome SNPs were analyzed in 96 Kongu Vellalar caste population of Tamil Nadu, and compared the results with the available data from the Indian subcontinent. It was observed that all the individuals of Kongu Vellalar caste population were falling in macrohaplogroup M and N. Further, subhaplogrouping of “M” revealed that Kongu Vellalar caste population was falling in haplogroup M*, M35 and M5. On the other hand at the Y chromosome haplogroup level 29% of the studied Kongu Vellalar caste population falls in Indian specific haplogroup M82-H1a. Our study concluded that there might be an admixture of this population with the surrounding Austro-Asiatic populations.

Andrews RM, Kubacka I, Chinnery PF, Lightowlers RN, Turnbull DM, Howell N. 1999. Reanalysis and revision of the Cambridge reference sequence for human mitochondrial DNA. Nat Genet. 23,147.

Bamshad M, Kivisild T, Watkins WS, Dixon ME, Ricker CE. Rao BB. 2001. Genetic evidence on the origins of Indian caste populations. Genome Res.11, 994–1004.

Bamshad MJ, Wooding S, Watkins WS, Ostler CT, Batzer MA. 2003. Human population genetic structure and inference of group membership. Am J Hum Genet.72, 578 – 589.

Basu A, Mukherjee N, Roy S, Sengupta S, Banerjee S, Chakraborty M. 2003. Ethnic India: a genomic view, with special reference to peopling and structure. Genome Res. 13, 2277–2290.

Cavalli-Sforza LL, Menozzi P, Piazza A. 1994. The history and geography of human genes. Princeton, NJ: Princeton University Press.

Giles Richard E, Blanc H, Cann HM, Wallace DC. 1980. Maternal inheritance of human mitochondrial DNA. PNAS 77, 6715–6719.

Jeanmougin F, Thompson JD, Gouy M, Higgins DG, Gibson TJ. 1998. Multiple sequence alignment with Clustal X. Elsevier Science.

Jobling MA, Tyler Smith C. 2003. The human Y chromosome: an evolutionary marker comes of age. Nat Rev Genet. 4, 598–612.

Kivisild T, Bamshad MJ, Kaldma K, Metspalu M, Metspalu E, Reidla M. 1999. Deep common ancestry of Indian and western-Eurasian mitochondrial DNA lineages. Curr Biol. 9, 1331–1334.

Kivisild T, Rootsi S, Metspalu M, Mastana S, Kaldma K, Parik J. 2003. The genetic heritage of the earliest settlers persists both in Indian tribal and caste populations. Am J Hum Genet.72, 313–332.

Kumar S, Tamura K, Nei M. 2004. MEGA3: Integrated software for Molecular Evolutionary Genetics Analysis and sequence alignment. Briefings in bioinformatics.52.150–163.

Mark AJ, Chris Tyler-Smith. 2003. The human Y chromosome: an evolutionary marker comes of age. Nature reviews genetics. 4. 598-612

Metspalu M, Kivisild T, Metspalu E, Parik J, Hudjashov G, Kaldma K. 2004. Most of the extant mtDNA boundaries in South and Southwest Asia were likely shaped during the initial settlement of Eurasia by anatomically modern humans. BMC Genet. 5, 26.

Petraglia MD, Allchin B. 2007. The evolution and history of human populations in south Asia. 229-244, Springer. 229– 244.

Thangaraj K, Chaubey G, Kivisild T, Reddy AG, Singh VK, Rasalkar A. 2005. Reconstructing the origin of Andaman Islanders. Science. 13, 996.

Thangaraj K, Joshi MB, Reddy AG, Gupta NJ, Chakravarty B, Singh L. 2002. CAG repeat expansion in the androgen receptor gene is not associated with male infertility in Indian populations. J Androl. 23, 815-818.

Related Articles

Hepatoprotective and antinociceptive effects of terpinolene in streptozotocin-induced diabetic peripheral neuropathic rats

Ravishankar Sarumathi, Muthukumaran Preethi, Chandrasekaran Sankaranarayanan*, Int. J. Biosci. 27(6), 156-166, December 2025.

Agromorphological characterization of six promising bambara groundnut [Vigna subterranea (L.) Verdc.] genotypes under selection in Burkina Faso

Adjima Ouoba*, Ali Lardia Bougma, Dominique Nikiéma, Mahamadi Hamed Ouédraogo, Nerbéwendé Sawadogo, Mahama Ouédraogo, Int. J. Biosci. 27(6), 145-155, December 2025.

Integrated in silico and in vitro analyses reveal E-cadherin crosstalk and TF: FVIIa complex-mediated trophoblast motility via MEK/JNK activation

Kirthika Manoharan, Jagadish Krishnan, Vijaya Anand Arumugam, Shenbagam Madhavan*, Int. J. Biosci. 27(6), 136-144, December 2025.

Effect of flooding depth and harvest intensity on soil moisture dynamics and production of baobab (Adansonia digitata) seedlings

Sissou Zakari, Pierre G. Tovihoudji, Mouiz W. I. A. Yessoufou, Sékaro Amamath Boukari, Vital Afouda, Imorou F. Ouorou Barrè, Int. J. Biosci. 27(6), 127-135, December 2025.

Local food processing and associated hygienic quality in greater Lomé, Togo: Traditional cooked corn-based dough akpan wrapped in M. cuspidata, M. mannii and M. purpurea species leaves

Mamy Eklou, Komlan Edjèdu Sodjinou, Kodjo Djidjolé Etse, Awidèma Adjolo, Benziwa Nathalie Johnson, Bayi Reine Dossou, Yaovi Ameyapoh, Raoufou Radji, Akossiwoa M-L Quashie, Int. J. Biosci. 27(6), 114-126, December 2025.

Improving the microbiological quality of spices and spice blends using treatments accessible to SMEs/SMIs

Pingdwindé Marie Judith Samadoulougou-Kafando, Korotimi Traoré, Crépin Ibingou Dibala, Aboubacar Sidiki Dao, Josias Nikiema, Idrissa Taram, Adama Pare, Inoussa Salambéré, Donatien Kaboré, Charles Parkouda, Int. J. Biosci. 27(6), 102-113, December 2025.

Twin-row planting practice in village sugarcane (Saccharum officinarum L.) plantations during first ratoon under rainfed conditions in northern Côte d’Ivoire

Allé Yamoussou Joseph, Sawadogo Fatima, Traoré Mohamed Sahabane, Fondio Lassina, Int. J. Biosci. 27(6), 91-101, December 2025.

Prevalence of dengue infection in Delta State, Nigeria

P. A. Agbure, O. P. G. Nmorsi, A. O. Egwunyenga, Int. J. Biosci. 27(6), 82-90, December 2025.