Study of blood groups and Rhesus factor in beta thalassemia patients undergoing blood transfusions
Paper Details
Study of blood groups and Rhesus factor in beta thalassemia patients undergoing blood transfusions
Abstract
Beta thalassemia is the most common genetic blood disease, affecting millions of people in both developing and developed countries including Iraq. Patients with thalassemia require frequent blood transfusions, which can cause a variety of complications. Several researches have looked into the link between ABO blood groups and diseases. The associations of ABO blood group with thalassemia have not been extensively studied. In order to know the prevalence of thalassemia according to age, gender and blood group frequency, a study was conducted on 200 individuals, 100 of them were a control sample, which was considered a standard sample, while the rest 100 individuals were infected with beta thalassemia. The study aims to find out any relationship between the frequency of blood group phenotypes and susceptibility to thalassemia compared to the control sample. Our findings indicate that the prevalence of thalassemia was higher in female patients than in male patients. Found in the lowest age group 15-19 years. There was a significant difference (P 0.05) in the frequency of ABO blood groups that was O > B > A > AB. A significant difference of Rh factor (P<0.01) was found in the patients compared with the control group. The current study indicated the importance of the studied blood groups, as they are sources for detecting the risks of inheriting beta thalassemia or the variability in the likelihood of its appearance, and they can be used with other laboratory tests in genetic counseling.
Abdollahi A, Qorbani M, Salehi A, Mansourian M. 2009. ABO blood groups distribution and cardiovascular major risk factors in healthy population. Iranian Journal of Public Health 38(3), 123-126.
Ahmed Kiani R. 2016. Epidemiology of transfusion transmitted infection among patients with βthalassemia major in Pakistan. Journal of blood transfusion.
AL-Assadi AZM. 2007. Genetic biodiversity of some mutation association with beta thalassemia in Iraq. Phd. Thesis, Inst Genet. Eng. Biotchnol. post Grad. stud., Univ. Baghdad : 124pp.
Anstee DJ. 2010. The relationship between blood groups and disease. Blood 115, 4635‑4.
Bdollahi A, Qorbani M, Salehi A, Mansourian M. 2009. ABO blood groups distribution and cardiovascular major risk factors in healthy population. Iranian Journal of Public Health 38(3), 123‑126
Canatan D, Oguz N, Balta N, Cosan R, Karadogan C, Ozancak A, Dircan H, Cengiz O, Alanglu G. 2003. Red cell antibodies in patients with b-thalasseia major. b. b. transfus. Med. 1(1), 31-34.
Chou ST. 2013. Transfusion therapy for sickle cell disease: a balancing act. Hematology 2013(1), 439-446.
Hood AM, King AA, Fields ME, Ford AL, Guilliams KP, Hulbert ML, White DA. 2019. Higher executive abilities following a blood transfusion in children and young adults with sickle cell disease. Pediatric blood & cancer 66(10), e27899.
Kondam A, Chandrasekhar M. 2012. A study of “incidence of hypertension in abo and rhesus blood group system. Int J. Boil Med Res 3(1), 1426‑1429.2.
Laghari ZA, Baig NM, Charan TR, Lashari KH, Suhag R. 2001. Distribution of ABO blood groups and Rhesus factor in ß-thalassemia patients at Thalassemia Care Center Nawabshah, Pakistan. Sindh University Research Journal-SURJ (Science Series) 50(01), 123-128.
Marbut SMM, Hamdi MA, Jumaa AM, Salman BA. 2018.Distribution of ABO blood groups in beta thalassemia patients dependent on blood transfusion In Bagdad city. Journal of Madenat Alelem University College 10(2), 1-11.
Mohssin MY, Mahmood AE, Kamal SB, Batah EH. 2015. Frequency distribution of hemoglobin variant and ABO blood groups among thalassemia patients from Ibn-Al-Baladi pediatric hospital in Baghdad/Iraq. W J Pharma Pharmaceut Sci. 4(11), 31-9.
Mondal B, Maiti S, Biswas BK, Ghosh D, Paul S. 2012.Prevalence of hemoglobinopathy, ABO and rhesus blood groups in rural areas of West Bengal, India. J Res Med Sci. 17, 772‑76. 6.
Nishi K, Gupta NK, Sharma SC. 2012. Study on the Incidence of Hypertension and Migraine in ABO Blood Groups. ISCA Journal of Biological Sciences 1(2), 12‑16.3.
Pennap G, Envoh E, Igbawua I. 2011. Frequency distribution of Hemoglobin Variants, ABO and Rhesus Blood Groups among Students of African Descent. British Microbial, Res. J 1, 33-40. 5.
Pramanik T, Pramanik S. 2000. Distribution of ABO and Rh blood groups in Nepalese medical students: A report. Eastern Mediterr Health. J. 6(1), 156‑158.
Purohit P. 2014. Prevalence of deletional alpha thalassemia and sickle gene in a tribal dominated malaria endemic area of eastern India. ISRN hematology.
Rai JJ, Bisu S. 2017. Distribution of ABO blood groups and Rhesus factor percentage frequencies amongst the populations of Sikkim, India. National Science Academy 83(1).
Sinha PA, Mulkutkar SH, Bhavani JB. 2017. Study of distribution of ABO blood groups in ß-thalassemia patients. International Journal of Research in Medical Sciences 5(8), 3479-3483.
Watkins WM. 2001. The ABO blood group system: historical background. Transfusion medicine 11(4), 243-265.
Wu O, Bayoumi N, Vickers M, Clark P. 2008. ABO blood groups and vascular disease: A systematic review and meta‑analysis. J. Thromb Haemost 6, 62-9. 7.
Maha Tareq Hussein (2021), Study of blood groups and Rhesus factor in beta thalassemia patients undergoing blood transfusions; IJBB, V13, N6, December, P1-6
https://innspub.net/study-of-blood-groups-and-rhesus-factor-in-beta-thalassemia-patients-undergoing-blood-transfusions/
Copyright © 2021
By Authors and International
Network for Natural Sciences
(INNSPUB) https://innspub.net
This article is published under the terms of the
Creative Commons Attribution License 4.0