Study of the lipid profile of malnourished people living with HIV monitored at the Notre Dame Apôtres Hospital in Sarh, CHAD

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Research Paper 14/12/2023
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Study of the lipid profile of malnourished people living with HIV monitored at the Notre Dame Apôtres Hospital in Sarh, CHAD

Isabelle Sacramento, Odile Soudonou, Pascaline B. Tiamou N'Koue, Chantal Hounkpatin, Alphonse Sezan, Jean Marc Atègbo
Int. J. Biosci.23( 6), 249-254, December 2023.
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Abstract

HIV/AIDS remains a major public health problem with a high morbidity and mortality rate. The nutritional status of infected persons is weakened for pathophysiological reasons related to the infection and because PLWHIV often have diets relatively low in energy, protein and other nutrients, which may affect the progression of the infection by weakening the immune system with the advent of opportunistic infections and metabolic abnormalities including dyslipidemias. The objective of the present study is to describe the lipid profile of people living with HIV malnuti followed at the NDA hospital in Sarh, Chad. It was a descriptive and analytical study. The study population consisted of people living with HIV followed up at the NDA hospital in Maïngara, Sarh. The lipid profile was assessed by the lipid balance performed in fasting patients. A total of 34 patients were included in the study. Women were predominant (74%). The average age was 43 ± 5 years. Total hypercholesterolemia was observed in 06 patients (17.65%), LDL hypercholesterolemia in 01 patient (2.94%) with pathological LDL hypocholesterolemia observed in 25 patients (73.53%), HDL hypocholesterolemia in 68 patients (27.87%) and hypertriglyceridemia in 44 patients (18.03%). Triglyceridemia to HDL cholesterol ratio was high in 05 patients (14.70%). Malnutrition was associated with dyslipidemia. The lipid profile of HIV infected patients in the present study is characterized by the presence of dyslipidemias promoted by malnutrition.

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