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Synthesis and comparative antimicrobial studies of some acylated d-glucofuranose and d-glucopyranose derivatives

Research Paper | August 1, 2013

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Mohammed M. Matin, M. M. H. Bhuiyan, Dulal C. Debnath, M. A. Manchur

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Int. J. Biosci.3( 8), 279-287, August 2013

DOI: http://dx.doi.org/10.12692/ijb/3.8.279-287

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Abstract

Some acylated D-glucofuranose (2, 3, 5, 6) and D-glucopyranose (8, 9) derivatives were prepared by direct acylation method for comparative antimicrobial studies. All the compounds (19) were screened for in vitro antibacterial activity against ten human pathogenic bacteria and antifungal activity against four pathogenic fungi. The study revealed that the D-glucopyranose derivatives were more prone towards antimicrobial functionality than that of the D-glucofuranose derivatives.

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Synthesis and comparative antimicrobial studies of some acylated d-glucofuranose and d-glucopyranose derivatives

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