Synthesis of copper oxide (CuO) nanostructures for antifungal and antibacterial activities

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Research Paper 01/10/2021
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Synthesis of copper oxide (CuO) nanostructures for antifungal and antibacterial activities

Ali Raza Rind, Riaz Hussain Mari, Abdul Raheem Shar, Shafi Muhammad Wassan, Zubeda Bhatti, Mazhar Ali Abbasi, Sayyad Sajjad Hussain Shah, Shahid Raza Rind, Saleem Ahmed Utero
J. Biodiv. & Environ. Sci. 19(4), 53-62, October 2021.
Copyright Statement: Copyright 2021; The Author(s).
License: CC BY-NC 4.0

Abstract

In current study, the morphology of copper (II) oxide nano-material was evaluated using, ethylene diamminetetraacetate as soft template via low temperature aqueous chemical growth technique. Scanning Electron Microscopy (SEM) was used to investigate the morphology of copper (II) oxide nanostructures and freshly developed CuO was observed to have spherical shape. X-ray Diffraction (XRD) method was used to study the crystalline quality of cuperic oxide which showed crystalline nature of high quality. Three types of bacteria and one type of fungi were selected to facilitate the antimicrobial activity of synthesized nanostructures. In this work it was declared that as concentration of CuO increases the inhibition zone also increases for all the three types of bacteria and fungi too. At the concentration of 1.0mg/L the inhibition zone found was as given below: pergillusniger>15.41mm, Agrobacterium tumefaciens> 21.5mm, Klebsiella pneumonia >23.6mm and E.coli>28.6mm. It was further found that E. coli was extra responsive to copper oxide.

Abbasi E, Milani M, Fekri Aval S, Kouhi M, Akbarzadeh A, TayefiNasrabadi H, Nikasa P, Joo SW, Hanifehpour Y, Nejati-Koshki K, Samiei M. 2016. Silver nanoparticles: synthesis methods, bio-applications and properties. Critical reviews in microbiology 42(2), 173-180.

Abbasi-Kesbi F, Rashidi AM, Astinchap B. 2018. Preparation of ultrafine grained copper nanoparticles via immersion deposit method. Applied Nanoscience 8(3), 221-230.

Abdelkader HS, Alhazmi NM. 2021. Disinfection of Tank Water Using Biogenic Silver Nanosilica as Anti-Microbial Agents in Jeddah City. Journal of Pharmaceutical Research International 14-34.

Ahamed M, Alhadlaq HA, Khan MA, Karuppiah P, Al-Dhabi NA. 2014. Synthesis, characterization, and antimicrobial activity of copper oxide nanoparticles. Journal of Nanomaterials.

Buazar F, Sweidi S, Badri M, Kroushawi F. 2019. Biofabrication of highly pure copper oxide nanoparticles using wheat seed extract and their catalytic activity: A mechanistic approach. Green processing and synthesis 8(1), 691-702.

D’Amato R, Ruggiero A, Valašek P, Ungureanu N. 2021. Nano Particles as Lubricant Additive: A Concise Review. In Advances in Manufacturing Engineering and Materials II: Proceedings of the International Conference on Manufacturing Engineering and Materials 392-403.

Darezereshki E, Bakhtiari F. 2013. Synthesis and characterization of tenorite (CuO) nanoparticles from smelting furnace dust (SFD). Journal of Mining and Metallurgy B: Metallurgy 49(1), 21-26.

Delgado K, Quijada R, Palma R, Palza H. 2011. Polypropylene with embedded copper metal or copper oxide nanoparticles as a novel plastic antimicrobial agent. Letters in applied microbiology 53(1), 50-54,

Elemike EE, Onwudiwe DC, Wei L, Chaogang L, Zhiwei Z. 2019. Noble metal–semiconductor nanocomposites for optical, energy and electronics applications. Solar Energy Materials and Solar Cells 201, 110106,

Hafeez M, Arshad R, Khan J, Akram B, Ahmad MN, Hameed MU, Haq S. 2019. Populusciliata mediated synthesis of copper oxide nanoparticles for potential biological applications. Materials Research Express 6(5), 055043.

KarMahapatra D, Kumar Bharti S, Asati V. 2017. Nature inspired green fabrication technology for silver nanoparticles. Current Nanomedicine (Formerly: Recent Patents on Nanomedicine) 7(1), 5-24.

Madkour LH. 2019. Introduction to nanotechnology (NT) and nanomaterials (NMs). In Nanoelectronic Materials Springer, Cham 1-47.

Mani VM, Kalaivani S, Sabarathinam S, Vasuki M, Soundari AJPG, Das MA, Elfasakhany A, Pugazhendhi A. 2021. Copper oxide nanoparticles synthesized from an endophytic fungus Aspergillusterreus: Bioactivity and anti-cancer evaluations. Environmental research 111502.

Montazer M, Harifi T. 2017. New approaches and future aspects of antibacterial food packaging: from nanoparticles coating to nanofibers and nanocomposites, with foresight to address the regulatory uncertainty. In Food packaging, 533-565, Academic Press.

Nayak R, Ali FA, Mishra DK, Ray D, Aswal VK, Sahoo SK, Nanda B. 2020. Fabrication of CuO nanoparticle: an efficient catalyst utilized for sensing and degradation of phenol. Journal of Materials Research and Technology 9(5), 11045-11059.

Nishanthi R, Malathi S, Palani P. 2019. Green synthesis and characterization of bioinspired silver, gold and platinum nanoparticles and evaluation of their synergistic antibacterial activity after combining with different classes of antibiotics. Materials Science and Engineering: C 96, 693-707.

Oussou-Azo AF, Nakama T, Nakamura M, Futagami T, Vestergaard MDCM. 2020. Antifungal potential of nanostructured crystalline copper and its oxide forms. Nanomaterials 10(5), 1003.

Perelshtein, Perkas N, Gedanken A. 2019. The sonochemical functionalization of textiles. The Impact and Prospects of Green Chemistry for Textile Technology 161-198.

Prasad RD, Charmode N, Shrivastav OP, Prasad SR, Moghe A, Sarvalkar PD, Prasad NR. 2021. A Review on Concept of Nanotechnology in Veterinary Medicine. ES Food & Agroforestry 4, 28-60.

Preeth DR, Shairam M, Suganya N, Hootan R, Kartik R, Pierre K, Suvro C, Rajalakshmi S. 2019. Green synthesis of copper oxide nanoparticles using sinapic acid: an underpinning step towards antiangiogenic therapy for breast cancer. JBIC Journal of Biological Inorganic Chemistry 24(5), 633-645.

Shankar S, Wang LF, Rhim JW. 2017. Preparation and properties of carbohydrate-based composite films incorporated with CuO nanoparticles. Carbohydrate polymers 169, 264-271.

Soliman WE, Khan S, Rizvi SMD, Moin A, Elsewedy HS, Abulila AS, Shehata TM. 2020. Therapeutic applications of biostable silver nano-particles synthesized using peel extract of Benincasahispida: Antibacterial and anticancer activities. Nanomaterials 10(10), 1954.

Vaseghi Z, Nematollahzadeh A. 2020. Nanomaterials: Types, Synthesis, and Characterization. Green Synthesis of Nanomaterials for Bioenergy Applications 23-82.

Vaseghi Z, Nematollahzadeh A. 2020. Types, Synthesis, and Characterization. Green Synthesis of Nanomaterials for Bioenergy Applications 23.

Zhao J, Stenzel MH. 2018. Entry of nanoparticles into cells: The importance of nanoparticle properties. Polymer Chemistry 9(3), 259-272.

Zottel A, VidetičPaska, Jovčevska I. 2019. Nanotechnology meets oncology: nanomaterials in brain cancer research, diagnosis and therapy. Materials 12(10), 1588.

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