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The alteration in the neuromasts of the system of the lateral line of a freshwater fish “Gambusia affinis” by various xenobiotics

Yousria Gasmi, Jean-Pierre Denizot, Mourad Bensouilah

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Int. J. Biosci.12(1), 278-292, January 2018

DOI: http://dx.doi.org/10.12692/ijb/12.1.278-292


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This work aims to alter the system of the lateral line by different treatment with the ototoxic antibiotic (gentamicin), the heavy metal which is cadmium and the pesticide Methyl parathion. The description of the cells of the lateral line system in a fish exposed or not exposed to different xenobiotics. A topographical and anatomical study of mechanoreceptors in the lateral line of the head of a teleostéen Gambusia affinis was conducted before and after exposure of the latter to specific doses of Gentamicin. Photonics microscopy shows that exposure to a daily mechanoreceptor dose of 80 mg of Gentamicin for 15 days engenders a separation of the cilia from the apex of the cell. However, the various component organ areas seem to keep structural integrity. However, the observation of the ultra-structure of ciliated sensory cell specimens treated with Gentamicin shows an alteration of the cell illustrated by the loss of the cilia of the apex and those synaptic structures of the basal cytoplasm. However, afferent and efferent endings are maintained. The increase in the dose of Gentamicin causes the acceleration of the degenerative process of the ciliated cell, but stopping the treatment brings about the unleashing of a regenerative process, which reveals the reversibility of the effect of the antibiotic on the ciliated sensory cell. Mechanoreceptor’s exposure to methyl parathion and cadmium in high doses 1 mg/l and 5 µg/l for a time interval of 7 days does not cause any change in the apical part of the cell. However, different areas making up the body seem to have retained their structural integrity.


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The alteration in the neuromasts of the system of the lateral line of a freshwater fish “Gambusia affinis” by various xenobiotics

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