The effect of dietary silver nanoparticles on performance, immune organs, and lipid serum of broiler chickens during starter period

Paper Details

Research Paper 01/05/2013
Views (624)
current_issue_feature_image
publication_file

The effect of dietary silver nanoparticles on performance, immune organs, and lipid serum of broiler chickens during starter period

Farhad Ahmadi, Mehran Mohammadi Khah, Saman Javid, Ayoub Zarneshan, Loghman Akradi, Pezhman Salehifar
Int. J. Biosci. 3(5), 95-100, May 2013.
Copyright Statement: Copyright 2013; The Author(s).
License: CC BY-NC 4.0

Abstract

This research was carried out to investigate the effect of silver nanoparticles (SNPs) on growth performance, immune organs, and serum lipids of broilers from 1 to 21 days of age. A total of 240 one-day-male broilers (Ross 308) distributed in four groups of 60 birds, including 4 replicates and 15 birds in each pen. Birds were fed on experimental diets including: T1 (control) without SNPs, T2, T3 and T4 supplementation basal diet with 4, 8 or 12 mg SNPs per kg of diet, respectively. At 21 d about 5 ml bloods (4 birds per groups) was removed from bronchial vein of four birds per replicate. Serum removed by centrifuged and stored at -20°C till the start of analysis. After blood sampling, birds were slaughtered and then visceral organs removed. Although the weight of selected organs was calculated regarding the total live body weight of each birds. The results indicated that SNPs have no significant effects on the performance (P≥0.05), there is a relative increased weight in SI and liver compared to control group (P≤0.05). Considering the abort points, the bursa weight was decreased compared to control treatment (P≤0.05). In addition TG, LDL, VLDL, and uric acid increased significantly (P≤0.05) in all treated than the control, as well as, HDL had significantly (P≤0.05) decreased compared with control. Relative weight of bursa Fabricius decreased (P≤0.05) in birds fed supplementation diet with levels of SNPs compared with control, especially in T4 birds. In conclusion, the SNPS no suitable alternatives as growth performance, Therefore, because of the mention changes may lead to negative effect on performance, immune response and health of broiler chickens.

Oberdörster G. 2010. Safety assessment for nanotechnology and nanomedicine: concepts of nanotoxicology. Journal of Internal Medicine. 267, 89-105. http://dx.doi.org/10.1111/j.1365-2796.2009.02187.x

Hansen SF, Michelson ES, Kamper A, Borling P, Stuer-Lauridsen F, Baun A. 2008. Categorization framework to aid exposure assessment of nanomaterials in consumer products. Ecotoxicology 17, 438-47. http://dx.doi.org/10.1007/s10646-008-0210-4

Lok CN, Ho CM, Chen R, He QY, Yu WY, Sun H .2007. Silver nanoparticles: partial oxidation and antibacterial activities. Journal of Biological Inorganic Chemistry 12, 527-53. http://dx.doi.org/10.1007/s00775-007-0208-z

Sawosa E, Bineka M, Grodzik M, Zieliskaa M, Sysaa P, Szmidt M. 2007. Influence of hydro colloidal silver nanoparticles on gastrointestinal microflora and morphology of enterocytes of quails. Archives of Animal Nutrition 6, 444-451. http://dx.doi.org/10.1080/17450390701664314

Grodzik M, Sawosza E. 2008. The influence of silver nano particles on chicken embryo development and bursa of Fabricius morphology. Journal of Animal and Feed Science. 15 (Suppl.) 1, 111-114.

Ahmadi, F, Rahimi, F. 2011. The effect of different levels of nanosilver on performance and retention of silver in edible tissues of broilers. World Applied Sciences Journal 12, 1- 4.

National Research Council.1994. Nutrient Requirements for Poultry, 9thed; National Academy of Sciences: Washington, DC, USA.

SAS Software, Version 9.1.2009. SAS Institute Inc: Cary, NC, USA.

Ahmadi F, Hafsi-Kurdestani A.2010. The Impact of silver nanoparticles on growth performance, lymphoid organs, and oxidative stress indicators in broiler chicks. Global Veterinaria 5, (6), 312-317.

Keller AA, Wang H, Zhou D, Lineman HS, Cherri G, Cardinale G.2010. Stability and aggregation of metal oxide nanoparticles in natural aqueous matrices. Environmental. Science. Technology.44,1962-1967. http://dx.doi.org/10.1021/es902987d

Yildirimer L, Thanh NTK, Loizidou M, Seifalian AM. 2011. Toxicology and clinical potential of nanoparticles. Nanotechnology Today.6, 585-607. http://dx.doi.org/10.1021/es902987d

Jia H, Hou W, Wei L, Xu B, Liu X. 2008. The structures and antibacterial properties of nano-SiO2 supported silver/zinc-silver materials, Dentist. Materials. 24, 244-249. http://dx.doi.org/10.1016/j.dental.2007.04.015

Savolainen K, Alenius H, Norppa H, Pylkkänen L, Tuomi T, Kasper G. 2010. Riskassessment of engineered nanomaterials and nanotechnologies- a review. Toxicology. 269, 92-104. http://dx.doi.org/10.1069/j.Tox.20.10.013

Ema, M, Kobayashi, N, Naya, M, Hanai, S, Nakanishi, J. 2010. Reproductive and developmental toxicity studies of manufactured nanomaterials, Reproduction. Toxicology. 30, 343– 352. http://dx.doi.org/10.1016/j. reprotox.2010.06.002

Tang M, Zhang T, Xue Y, Wang S, Huang M, Yang, GT. 2011. Metabonomic studies of biochemical changes in the serum of rats by intratracheally instilled TiO2 nanoparticles. J Nanoscience Nanotechnology. 11, 3065-3074. http://dx.doi.org/10.1166/jnn.2011.3604

Liu H, Yang D, Zhang H, Yang H. 2010.The immune toxic induced by 3 kinds of typical nanometer materials in rats. Journal Prev Medicine Chin PLA. 28, 163-166.

Landsiedel R, Ma-Hock L, Kroll A, Hahn D, Schnekenburger J, Wiench K, Wohlleben W. 2010. Testing metal-oxide nanomaterials for human safety. Advance Materials 22, 2601-2627. http://dx.doi.org/10.1002/adma.200902658

Related Articles

Medicinal plants sold in Daloa markets: Traditional knowledge and Public health issues

Kouakou Yao Bertin, Kouakou Assoman Serge Alain, Kouame Yao Anicet Gervais, Malan Djah François, Bakayoko Adama, Int. J. Biosci. 27(2), 200-210, August 2025.

Agronomic performance and profitability of coffee wildlings using different soil media mixtures

Maribel L. Fernandez, Ricardo B. Casauay, Ronel A. Collado, Int. J. Biosci. 27(2), 189-199, August 2025.

Implications of aberrant glycosylation on age-related disease progression

Tahmid Ahmad Patwary, Mukramur Rahman, Md. Nafis Fuad Prottoy, Sayad Md. Didarul Alam, Int. J. Biosci. 27(2), 176-188, August 2025.

Design and development of solar powered water sprayer: A green technology innovation

Lorenzo V. Sugod, Int. J. Biosci. 27(2), 159-175, August 2025.

Knowledge, attitudes, practices, and social awareness regarding SARS-CoV-2 infection in the kyrgyz population in the post-pandemic period

Mirza Masroor Ali Beg, Haider Ali, Yahya Nur Ahmed, Yavuz Gunduz, Hafsa Develi, Tilekeeva UM, Int. J. Biosci. 27(2), 151-158, August 2025.

Tumor suppressing ability of myrtenal in DMBA-induced rat mammary cancer: A biochemical and histopathological evaluation

Manoharan Pethanasamy, Shanmugam M. Sivasankaran, Saravanan Surya, Raju Kowsalya, Int. J. Biosci. 27(2), 141-150, August 2025.

Assessing tree diversity in cashew plantations: Environmental and agronomic determinants in buffer zones of Mont Sangbé National Park, western Côte d’Ivoire

Kouamé Christophe Koffi, Kouakou Hilaire Bohoussou, Serge Cherry Piba, Naomie Ouffoue, Sylvestre Gagbe, Alex Beda, Adama Tondossama, Int. J. Biosci. 27(2), 122-133, August 2025.