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The effect of dietary silver nanoparticles on performance, immune organs, and lipid serum of broiler chickens during starter period

Farhad Ahmadi, Mehran Mohammadi Khah, Saman Javid, Ayoub Zarneshan, Loghman Akradi, Pezhman Salehifar

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Int. J. Biosci.3(5), 95-100, May 2013

DOI: http://dx.doi.org/10.12692/ijb/3.5.95-100


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This research was carried out to investigate the effect of silver nanoparticles (SNPs) on growth performance, immune organs, and serum lipids of broilers from 1 to 21 days of age. A total of 240 one-day-male broilers (Ross 308) distributed in four groups of 60 birds, including 4 replicates and 15 birds in each pen. Birds were fed on experimental diets including: T1 (control) without SNPs, T2, T3 and T4 supplementation basal diet with 4, 8 or 12 mg SNPs per kg of diet, respectively. At 21 d about 5 ml bloods (4 birds per groups) was removed from bronchial vein of four birds per replicate. Serum removed by centrifuged and stored at -20°C till the start of analysis. After blood sampling, birds were slaughtered and then visceral organs removed. Although the weight of selected organs was calculated regarding the total live body weight of each birds. The results indicated that SNPs have no significant effects on the performance (P≥0.05), there is a relative increased weight in SI and liver compared to control group (P≤0.05). Considering the abort points, the bursa weight was decreased compared to control treatment (P≤0.05). In addition TG, LDL, VLDL, and uric acid increased significantly (P≤0.05) in all treated than the control, as well as, HDL had significantly (P≤0.05) decreased compared with control. Relative weight of bursa Fabricius decreased (P≤0.05) in birds fed supplementation diet with levels of SNPs compared with control, especially in T4 birds. In conclusion, the SNPS no suitable alternatives as growth performance, Therefore, because of the mention changes may lead to negative effect on performance, immune response and health of broiler chickens.


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The effect of dietary silver nanoparticles on performance, immune organs, and lipid serum of broiler chickens during starter period

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