The effect of some food additive on the liver function in laboratory animal

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Research Paper 01/10/2018
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The effect of some food additive on the liver function in laboratory animal

Sabreen Majeed Mohammed
Int. J. Biosci.13( 4), 18-23, October 2018.
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Phosphorus is an essential element as it represents the second most abundant mineral in the human body. Therefore, this study was designed to investigate the effect of phosphoric acid additive in water on some hematological and biochemical parameters in rabbits. Twelve female adult rabbits were divided randomly into two groups equally. The first group received 10% of phosphoric acid in water while the second group was received tap water as control group. The blood was collected in zero day and in 66 day. The result revealed that the Aspartate Aminotransferase (AST), Alanine Aminotransferase (ALT), Alkaline Phosphatase (ALP) and inorganic phosphorus were significantly increased (P <0.05) in serum of treated group as compared with control group, while the total calcium concentration was significantly decreased (P <0.05) in serum of treated group in comparison with control group. On the other hand the results of the hematological parameters showed a significant decreasing (P <0.05) in the RBC count, Hb and PCV of the treated group, whereas the WBC count was significantly (P<0.05) increased in the treated group. In conclusion, the phosphoric acid additive in water caused several changes in some biochemical and hematological parameters in rabbits.


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