The effects of zinc oxide nanoparticles on performance, digestive organs and serum lipid concentrations in broiler chickens during starter period

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Research Paper 01/07/2013
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The effects of zinc oxide nanoparticles on performance, digestive organs and serum lipid concentrations in broiler chickens during starter period

Farhad Ahmadi, Yahya Ebrahimnezhad, Naser Maheri Sis, Jamshid Ghiasi Ghalehkandi
Int. J. Biosci. 3(7), 23-29, July 2013.
Copyright Statement: Copyright 2013; The Author(s).
License: CC BY-NC 4.0

Abstract

The aim of current study was to investigate the effect of different levels of zinc oxide nanoparticles (ZONPs) on growth Performance, digestive organs and serum lipids concentration in broiler chickens during starter phase (1-21d). Three hundred one-d-old broilers (Ross- 308) were randomly divided into 5 treatments including 75 birds. All treatments were replicated 4 times, using 15 birds in each pen. The experimental diet was T1) basal diet (control, without ZONPs), T2, T3, T4 and T5 supplementation basal diet with 30, 60, 90 and 120 mg/kg of ZONPs respectively. This study was lasted 21 d and birds accessed as ad libitum to feed and water throughout research. Live body weight (LBW) and feed intake (FI) measured as weekly and feed conversion ratio (FCR) calculated at the final of research. On d 21, 4 birds in each group were selected as randomly, blood samples collected from bronchial vein and after centrifuging (3000 rpm for 15 min at 4°C), serum removed and stored in – 20 °C until analysis. The results revealed that ZONPs had significantly affected on body weight gain (P<0.05) and feed intake (P <0.05) among treatments including ZONPs and control group from 1 to 21 d. The feed intake was significantly decreased at levels of 60 and 90 mg/kg of ZONPs. As well, feed conversion ratio had significantly decreased (P<0.05) at the level of 60 mg/kg of ZONPs compared with control and others groups. ZONPs had resulted in low density lipoproteins (LDL) (P>0.05), triglyceride (TG) (P>0.05) and cholesterol (P>0.05), as well as increased high density lipoproteins (HDL) (P<0.05), respectively compared to control treatment. In conclusion, ZONPs can improve growth performance especially at the levels of 30 to 90 mg/kg of diet in broiler chickens.

Ahmadi F, Fariba R. 2010. The effect of different levels of nanosilver on performance and retention silver in edible tissue of broilers. World Applied Science Journal, 12, 1-4.

Analytical Methods for Atomic Absorption Spectrophotometery, 1982. Perkin-Elmer Corp., Norwalk, CT.

AOAC. 2000. Official Methods of Analysis 15th ed. Association of Official Analytical Chemists. Arlington, VA.

Bao YM, Choct M. 2009. Trace mineral nutrition for broiler chickens and prospects of application of organically complexed trace minerals: a review. Animal Prod Science, 49, 269-282. http://dx.doi.org/10.1071/EA08204

Bartlett JR, Smith MO. 2003. Effects of different levels of zinc on the performance and immunocompetence of broilers under heat stress. Poultry Science journal, 82, 1580-1588.

Bennet PM, Jepson PD, Law RJ, Jones BR, Kuiken T, Baker JR, Rogan E, Kirkwood JK. 2001. Exposure to heavy metals and infectious disease mortality in harbour porpoises from England and Wales. Environmental Pollution, 112, 33–40. http://dx.doi.org/10.1016/S0269-7491(00)00105-6

Cesur S, Cebeci SA, Kavas GO, Aksaray S, Tezerenv. 2005. Serum copper and zinc concentrations in patients with chronic hepatitis. British Journal of Infection Control, 51, 38–40. http://dx.doi.org/10.1016/j.jinf.2004.08.003

Duncan. 1995. Multiple range and F-tests. Biometrics Longman, New York, 11, 1-42.

Halifeoglu I, GUR B, AYDIN S, OZTURK. 2004. Plasma trace elements, vitamin B12, folate, and homocysteine levels in cirrhotic patients compared to healthy controls. Biochemistry, 69, 693–696.

Huang YL, Lu L,  Luo XG, Liu B. 2007. An optimal dietary zinc level of broiler chicks fed a corn-soybean meal diet. Poultry Science journal, 86, 2582-2589. http://dx.doi.org/10.3382/ps.2007-00088

Hudson  BP,  Dozier  WA,  Wilson  JL.  2004. Broiler live  performance  response  to  dietary  zinc source and the influence of zinc supplementation in broiler breeder diets. Animal feed Science and Technology, 118, 329-335. http://dx.doi.org/10.1016/j.anifeedsci.2004.10.018

Iji PA, Saki A, Tivey DR. 2001. Body and intestinal growth of broiler chicks on a commercial starter diet, Intestinal weight and mucosal development. British Poultry Science, 42, 505-513. http://dx.doi.org/10.1080/00071660120073151

Jahanian R, Moghaddam HN, Rezaei A. 2008. Improved broiler chick performance by dietary supplementation of organic zinc sources. Asian-Australas. Journal Animal Science, 21, 1348–1354.

Malcolm-Callis KJ, Duff GC, Gunter SA, Kegley EB, Vermeire DA. 2000. Effects of supplemental zinc concentration and source on performance, carcass characteristics, and serum values in finishing beef steers. Journal of Animal Science, 78, 2801-2808.

Mengheri E, Bises G, Gaetani. 1988. Differentiated cell-mediated immune response in zinc deficiency and in protein malnutrition. Nutrition Research, 8, 801-812.

National Research Council (NRC). 1994. Nutrient requirements of poultry. 9th Edition, National Academy Press, Washington DC.

Oteiza PL, Olin KL, Fraga CG, Keen CL. 1996. Oxidant defense systems in testes from Zn deficient rats. Proc. Soc. Exp. Biol. Med, 213, 85–91. http://dx.doi.org/10.1016/j.mam.2005.07.012

Pimental JL, Cook ME, Greger JL. 1991. Immune response of chicks fed various levels of zinc. Poultry Science journal, 70, 947-954. http://dx.doi.org/10.3382/ps.0700947

Powell SR. 2000. The antioxidant properties of zinc. Journal Nutrition, 130, 1447S – 1454S.

Prasad AS, Kucuk O. 2002. Zinc in cancer prevention. Cancer Metastasis Rev, 21, 291–295.

Syama S, Reshma SC, Sreekanth PJ, Varma HK, Mohanan PV. 2013. Effect of Zinc Oxide nanoparticles on cellular oxidative stress and antioxidant defense mechanisms in mouse liver. Toxicological and Environmental Chemistry, 22, 21-26. http://dx.doi.org/10.1080/027722 48.2013.789606

Sharma V, Poonam S, Alok KP, Alok D. 2012. Induction of oxidative stress, DNA damage and apoptosis in mouse liver after sub-acute oral exposure to zinc oxide nanoparticles. Mutation Research, 745, 84- 91.

SAS. 0223. SAS/STAT User’s Guide: Statistics, Release 6 . SAS Institute Inc., Cary, NC.

Sawosza, E, Bineka M, Grodzika M, Zieliñskaa M, Szmidt P, Niemiec M, Chwalibog A. 2007. Influence of hydro colloidal silver nanoparticles on gastrointestinal micro flora and morphology of enterocytes of quails. Animal Nutrition, 61, 444-451. http://dx.doi.org/10.10 80/17450390701664314

Sunder GS, Panda AK, Gopinath NCS, Rao SVR, Raju M, Reddy MR, Kumar CV. 2008. Effects of higher levels of zinc supplementation on performance, mineral availability, and immune competence in broiler chickens. Journal of Applied Poultry Research, 17, 79–86. http://dx.doi.org/10.1071/AN12291

Walravens PA. 1979. Zinc metabolism and its implications in clinical medicine (Clinical Nutrition Symposium). Western Journal of Medicine, 130, 133–142.

Wang HL, Zhang JS, Yu HQ. 2007. Elemental selenium at nano size possesses lower toxicity without compromising the fundamental effect on selenoenzymes: Comparison with selenomethionine in mice. Free Radical Biological Medicine, 42, 1524-1533.

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