The effects of zinc oxide nanoparticles on performance, digestive organs and serum lipid concentrations in broiler chickens during starter period

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Research Paper 01/07/2013
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The effects of zinc oxide nanoparticles on performance, digestive organs and serum lipid concentrations in broiler chickens during starter period

Farhad Ahmadi, Yahya Ebrahimnezhad, Naser Maheri Sis, Jamshid Ghiasi Ghalehkandi
Int. J. Biosci.3( 7), 23-29, July 2013.
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Abstract

The aim of current study was to investigate the effect of different levels of zinc oxide nanoparticles (ZONPs) on growth Performance, digestive organs and serum lipids concentration in broiler chickens during starter phase (1-21d). Three hundred one-d-old broilers (Ross- 308) were randomly divided into 5 treatments including 75 birds. All treatments were replicated 4 times, using 15 birds in each pen. The experimental diet was T1) basal diet (control, without ZONPs), T2, T3, T4 and T5 supplementation basal diet with 30, 60, 90 and 120 mg/kg of ZONPs respectively. This study was lasted 21 d and birds accessed as ad libitum to feed and water throughout research. Live body weight (LBW) and feed intake (FI) measured as weekly and feed conversion ratio (FCR) calculated at the final of research. On d 21, 4 birds in each group were selected as randomly, blood samples collected from bronchial vein and after centrifuging (3000 rpm for 15 min at 4°C), serum removed and stored in – 20 °C until analysis. The results revealed that ZONPs had significantly affected on body weight gain (P<0.05) and feed intake (P <0.05) among treatments including ZONPs and control group from 1 to 21 d. The feed intake was significantly decreased at levels of 60 and 90 mg/kg of ZONPs. As well, feed conversion ratio had significantly decreased (P<0.05) at the level of 60 mg/kg of ZONPs compared with control and others groups. ZONPs had resulted in low density lipoproteins (LDL) (P>0.05), triglyceride (TG) (P>0.05) and cholesterol (P>0.05), as well as increased high density lipoproteins (HDL) (P<0.05), respectively compared to control treatment. In conclusion, ZONPs can improve growth performance especially at the levels of 30 to 90 mg/kg of diet in broiler chickens.

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