The impact of cobalt chloride on enzyme activity of mice

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Research Paper 01/08/2019
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The impact of cobalt chloride on enzyme activity of mice

Khalid H. Gathwan, Khalil Ismail A. Mohamed, Mohammed Sami Kadhim
Int. J. Biosci.15( 2), 92-94, August 2019.
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Liver is a primary site of toxic and plays important role metabolism, any changes in cobalt concentration in blood; this may affect the activities of antioxidant enzymes for adult male mice. (80) Days old, weighing 30- 35 gm., were treated orally COCl2 (15, 30, 45) mg / kg Body weight for 30 days. The acid phosphatase, alkaline phosphatase in the plasma and liver were estimated. There was a significant increasing in the activity of enzyme (p<0.05), these enzyme with moderate and high dose (30, 45) while no change with low dose (15). This investigation concluded that COCl2 caused increasing in the levels of enzyme with increase of dose.


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