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Thrombolytic and allelopathic activities of medicinal plant: Strobilanthes urticifolia Wall. Ex Kuntze.

Research Paper | December 1, 2017

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Arshad Farid, Bashir Ahmad, Kashif Bashir, Yaqoob ur Rehman, Shafiullah Khan

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Int. J. Biosci.11( 6), 39-44, December 2017

DOI: http://dx.doi.org/10.12692/ijb/11.6.39-44


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Indigenous knowledge and literature review reveals that there is no such information or citation is available on proposed study and was aimed to evaluate the crude methanolic extract (CME)and different fractions of Strobilanthes urticifolia Wall. ex Kuntze for thrombolytic and allelopathic activities. CME and different fractions were tested against clot lytic activity in the thrombolytic test and the result showed that crude methanolic extract (56.11%) and chloroform fraction (64.94%) havehighest thrombolytic activity followed by n-hexane fraction (29.66%) while effect of ethyl acetate fraction (7.58%) and aqueous fraction (9.88%) on the blood clots ware almost negligible as compared to positive controlstreptokinase (SK) and negative control water which showed 76.44% and 5.97 % lysis of clot respectively. Only aqueous fraction was checked for the presence of allelochemicals in allelopathic activity and the result showed that at low concentration (25 and 50 %) the germination was 70±3.50% and 60±2.00% respectively while at high concentration of aqueous fraction it was reduce to 40±3.50 as compared to negative control water. Moisture content, shoot and radical length of the wheat seed in allelopathic activity was also noted and it also reduced in dose-dependent (25, 50 and 100 %) manner.These results suggest that CME and different fractions of Strobilanthes urticifoliaWall.exKuntze has significant thrombolytic and allelopathic properties and needs further exploration.


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Thrombolytic and allelopathic activities of medicinal plant: Strobilanthes urticifolia Wall. Ex Kuntze.

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