Toxicological effects of the essential oil of Premna angolensis leaves used as a rice protector against Sitotroga cerealella (Lepidoptera: Gelechiideae)

Paper Details

Research Paper 16/06/2023
Views (312) Download (32)
current_issue_feature_image
publication_file

Toxicological effects of the essential oil of Premna angolensis leaves used as a rice protector against Sitotroga cerealella (Lepidoptera: Gelechiideae)

Elvis Adjalian, Philippe Sessou, Rodrigue Towanou, Bertin A. Gbaguidi, Guy Alain Alitonou, Félicien Avlessi, Dansou Kossou, Dominique KC. Sohounhloue
Int. J. Biosci.22( 6), 236-244, June 2023.
Certificate: IJB 2023 [Generate Certificate]

Abstract

Cereals are increasingly attacked by Sitotroga cerealella, a highly destructive and economically important insect pest. The need to control this micro Lepidoptera to reduce its pressure on rice stocks is therefore acute. Today, the use of plant extracts, particularly essential oils, is a promising natural alternative to synthetic insecticides in the fight against crop pests. The objective of this study was to evaluate the acute oral toxicity of Premna angolensis in rats in order to propose an effective means of controlling S. cerealella in rice stocks without adversely affecting human health. The toxicity of this essential oil was assessed in male Wistar rats at a single dose of 2000mg/kg. The animals’ behavior was observed for 14 days. The results showed that the lethal dose 50% (LD50) is strictly higher than 2000mg/Kg bw and that this extract does not influence the normal weight growth in the treated rats. Also, the evaluation of biochemical parameters of rats proved that P. angolensis essential oil is not toxic to the liver, kidneys and did not disturb lipid metabolism in rats at 2000mg/kg bw. Haematological analyses showed no significant difference from the control (p>0.05), however, the blood platelet count was significantly increased in treated rats compared to the control at the 5% threshold. Thus, essential oil treatments that could be applied at much lower doses to rice stocks could not be harmful to humans. It could therefore be used without risk by the rice industry to control S. cerealella.

VIEWS 42

Adegbola YP, et Sodjinou E. 2003. Analyse de la filière du riz au Benin INRAB; Porto Novo. 246 p.

Adjalian E, Sessou P, Odjo T, Figueredo G, Kossou D, Avlessi F, Menut C, Sohounhloué D. 2015. Chemical composition and insecticidal and repellent effect of essential oils of two Premna species against Sitotroga cerealella. J Insects 6. DOI: 10.1 155/2015/319045

Agourram. 2013. Les cahiers d’hématologie. 100p

Al-Habori M, Al-Aghbari A, Al-Mamary M, and Baker M. 2002. Toxicological evaluation of Catha edulis leaves: A long term feeding experiment in animals. Journal of Ethnopharmacology 83, 209-217.

Almança CCJ, Saldanhab SV, Sousaa DR, Trivilin LO, Nunesa LC, Porfírio LC, Marinhoc BG. 2011. Toxicological evaluation of acute and sub-chronic ingestion of hydroalcoholic extract of Solanum cernuum Vell. In mice. Journal of Ethnopharmacology 138, 508-512. Available: https://www.sciencedirect.com/science/article/pii/S0378874111007161

British Pharmacopoeia. 1980. 11. P. A. HMSO, London, UK

Costa-Silva JH, Lima CR, Silva ER, Ara´ujo AV, Fraga MA, Ribeiro A, Arruda CA, Lafayette SL, Wanderley AG. 2008. Acute and subacute toxicity of the Carapa guianensis Aublet (Meliaceae) seed oil. Journal of Ethnopharmacology 116, 495-500.

Da Silva AS, Wolkmer P, Costa MM, Tonin AA, Eilers TL, Gressler LT, Otto MA, Zanette RA, Santurio JM, Lopes STA, and Monteiro SG. 2010. Biochemical changes in cats infected with Trypanosoma evansi. Veterinary Parasitology 171, 48-52.

Degnon GR, Adjou ES, Metome G, Dahouenon-Ahoussi E. 2016. Efficacité des huiles essentielles de Cymbopogon citratus et de Mentha piperita dans la stabilisation du lait frais de vache au Sud du Bénin. Journal Biological Chemistry Sciences 10(4), 1894-1902. http://dx.doi.org/10.4314 /ijbcs.v10i4.37

Dossouhoui FV, Agossou SD, Adegbidi A, del Villar PM, Tossou CR, Lebailly P. 2017. Analyse de la rentabilité financière de la production de semence du riz au Bénin. Journal of Applied Biosciences 113, 11267-11275.

Faye D, Fall A, Leak S, Losson B, Geerts S. 2004. Influence of an experimental Trypanosoma congolense infection and plane of nutrition on milk production and some biochemical parameters in West African Dwarf goats. Acta Trop 93, 247-257.

Fiamohe R. 2018. La segmentation du marché urbain du riz local au Bénin: Une analyse par la méthode de classification par cluster. African Journal of Agricultural and Resource Economics 15(1), 1-13.

Gabriela C, Vasil E, Dumitru C, Cojocar U, Costic M, Elena C. 2005. L’étude de l’activité des quelques enzymes du stress oxydatif dans le tissu musculaire a des différents cyprinidés de culture. Annale de SAUAC 7(1), 1-4.

Hodge HC, Sterner JH. 1943. Determination of substances acute toxicity by LD B50B. Amer. American Industrial Hygiene Association 10, 93. Available: https://doi.org/10.12691/ajps-5-3-1

Kpadonou D, Allanto F, Kpadonou-kpoviessi B, Agbani P, Gbaguidi F, Baba-moussa L, Gbenou J, Moudachirou M, Kpoviessi S. 2019. Relations entre composition chimiquue activité antioxydante et toxicité des uiles essentielles de deux espèces de cymbopogon acclimatées au Bénin International Journal of Biological and Chemical Sciences 13(2), 1201-1209. Available: https:// doi.org/10.4314/ijbcs.v13i2.48

Lecomte. 1998. La place de l’hématologie clinique en médecine vétérinaire son importance dans la pratique quotidienne: Synthèse d’observations. Bulletin de l’Académie Vétérinaire de France 70, 249-253.

Marshall WJ, Bangert SK. 2005. Clinical Chemistry, 5th Edition. Elsevier, London, UK, 392p.

Mbaka GO, Adeyemi OO, Oremosu AA. 2010. Acute and sub-chronic toxicity studies of the ethanol extract of the leaves of Sphenocentrum jollyanum (Menispermaceae). American Journal of Agricultural and Biological Sciences 1(3), 265-272. Available: http://www.scihub.org/ABJNA

OCDE. 2001. Ligne directrice de l’OCDE pour les essais de produits chimiques-méthode par classe de toxicité aigüe.14p. Available: https://www.oecd-ilibrary.org/docserver/9789264071018

Olivier W. 2011. Risques liés aux nanoparticules et aux nanomatériaux. Annale de l’Institut National de Recherche et de Sécurité 19(1-4), 1-90.

OMS. 2009. Manuel: L’utilisation clinique du sang en Médecine interne Obstétrique Pédiatrie Chirurgie et anesthésie Traumatologie et soins aux brûlés 378p.

Pauly M. 2012. Structuration de nanoparticules magnétiques d’oxyde de fer en film et étude de leur propriétés magnétiques et magnéto transport. Thèse doctorat physique et chimie-physique, Strasbourg. 230p.

Pitel Ph, Moulin M, Valette JP, Dumontier S, Petit L, Fortier G, Couroucé-Malblanc A. 2006. Approche des valeurs hématologiques et biochimiques chez deux races asines. Pratique Vétérinaire Équine. 38, 19-25.

Pratt D, Kaplan M. 2000. Evaluation of abnormal liver-enzyme results in asymptomatic patients. New England Journal of Medecine 342, 1266-1271.

Pritchard JC, Burn CC, Barr AS, Whay HR. 2009. Haematological and serum biochemical reference values for apparently healthy working horses in Pakistan. Research Veterinary Science 87, 389-395.

Sacoti H. 2012. Lésions élémentaires des cellules, tissus et organes. Annale de COPATH 3(1), 1-29. College francais des pathologistes

Sangare M, Klotoe JR, Dougnon V, Ategbo JM, Laleye A, Edorh P, Fah L, Senou M, Loko F, Dramane LK. 2012. Evaluation of the hepatoprotective activity of Gomphrena celosioides (Amaranthaceae) on wistar rats intoxicated with tetrachloride carbon. International Journal of Currennt Research 4, 067-072.

Shen Y. 2009. Preparation and application of magnetic Fe3O4 nanoparticles for wastewater purification. Annale de SPT. vol. 68(3), 1-8.

Sirwal IA, Banday KA, Reshi AR, Bhat MA, Wani MM. 2004. Estimation of Glomerular Filteration Rate (GFR). JK Science 6, 121-123.

Song M, Moon K, Kim Y, Lim D, Song C, Yoon W. 2007. Labeling efficacy of superparamagnetic iron oxide nanoparticles to human neural stem cells: Comparison of ferumoxides, monocrystalline iron oxide, cross-linked iron oxide (CLIO)-NH2 and tat-CLIO. Annale de KJR 8(5), 1-24. 

Soumanou MM, Adjou ES. 2016. Sweet Fennel (Ocimum gratissimum) Oils. In Essential Oils in Food Preservation, Flavor and Safety Preedy VR (Ed). Academic Press 765-773. Available: https:// www.doi.org/10.1016/B978-0-12-416641-7.00087-0

Sow A, Sidibé I, Bengaly Z, Marcotty T, Séré M, Diallo A, Vitouley HS, Nebié RL, Ouédraogo M, Akoda GK, Van den Bossche P, Van Den Abbeele J, De Deken R, Delespaux V. 2012. Field detection of resistance to isometamidium chloride and diminazene aceturate in Trypanosoma vivax from the region of the Boucle du Mouhoun in Burkina Faso. Veterinary Parasitology 187, 105-111.

Whitby IG, Smith AF, Beckett GJ. 1988. Lecture note of clinical chemistry. 4th Edition, blackwell scientific publications, oxford. 154p.