Toxicological impact of hexavalent chromium on hematology and FSH, LH hormones of Ctenopharyngodon idella
Paper Details
Toxicological impact of hexavalent chromium on hematology and FSH, LH hormones of Ctenopharyngodon idella
Abstract
Heavy metal chromium influences the nutritive value of fish. The aim of this study is to scrutinize the effect of sub lethal dose of Cr (VI) on hematological parameters and endocrine hormones FSH and LH in the widely consumed fresh water fish Ctenopharyngodonidella. For this purpose, the experiment was designed to expose the fish to sublethal dose of hexavalent chromium (120 mg/l) for 7 days. After the stipulated time period blood was collected for hematological and hormonal studies and analysed through routine clinical methods. The results indicated a consistent reduction compared to control in the values of white blood cells (14.75%), hemoglobin (1.08%), red blood cells (11.11%), platelets (48.92%), platelet distribution width (6.76%), mean platelet volume (2.24%) and plateletcrit (46.35%). While increasing trend was noticed in hematocrit (59.17%), Mean corpuscular volume (3708.96%), Mean corpuscular hemoglobin (343.42%), Mean corpuscular hemoglobin concentration (96.48%). Among hormones follicle stimulating hormone and luteinizing hormone represented a non-significant elevation of 63.74% and 40.73%. Reduction of blood parameters represents severe hemolysis, anemic condition and retarded fish health. While increasing trend indicates activation of immune system against the Cr (VI) stress. Cr induced reproductive disruption by increasing level of FSH and LH.
Abedi Z, Khalesi MK, Kohestan Eskandari S, Rahmani H. 2012. Comparison of Lethal Concentrations (LC50-96 H) of Cdcl2, Crcl3, and Pb (NO3)2 in Common Carp (Cyprinus carpio) and Sutchi Catfish (Pangasius hypophthalmus). Iranian Journal of Toxicology 6(18), 672-80.
Adeyemo OK. 2007. Haematological profile of Clarias gariepinus (Burchell, 1822) exposed to lead. Turkish Journal of Fisheries and Aquatic Sciences 7, 163–169.
Ball JN, Baker BI. 1969. The pituitary gland: anatomy and histophysiology. In: Fish physiology (edt Hoar, W.S. and D.J. Randall), Val. II, New York and London, Academic Press, 1-110.
Bhatkar NV. 2011. Chromium (III) induced haematological alterations in Indian common carp, Labeo rohita (Ham.).Journal of Applied and Natural Science 3(2), 258 -263.
Bomford R, Mason S, Swash M. 1975. In: Hutchison’s clinical methods. The McMillon publishing company, Inc. N,Y.
Chaudhary R, Gaur KK, Kushwaha B, Nagpure NS, Kumar R, Singh A, Singh SP. 2018. Toxicological Effects of some biochemical parameters of fresh water fish Channa Punctatus (Bloch.) under the stress of Chromium nitrate. International Journal of Latest Technology in Engineering, Management & Applied Science 7, 312.
Dacie JV, Lewis SM. 1977. Practical haematology. Chuchill Living Stone, London. 5th Ed., p 297.
Dhanapakiam P, Ramasamy VK. 2001. Toxic effects of copper and zinc mixtures on some haematological and biochemical parameters in common carp, Cyprinus carpio (Linn). Journal of Environmental Biology 22, 105- 111.
Faheem M, Khaliq S, Ahmad HU, Lone KP. 2017. Bisphenol-A (BPA) alters plasma thyroid hormones and sex steroids in female Pakistani major carp (Catla catla; Cyprinidae). Pakistan Veterinary Journal 37(3), 326-330.
Fattahi E, Parivar K, Gholam S, Jorsarae A, Moghadamnia AK. 2009. The effects of diazinon on testosterone, FSH and LH levels and testicular tissue in mice. Iranian Journal of Reproductive Medicine 7, 59-64.
Fernandes MN, Mazon AF. 2003. Environmental pollution and fish gill morphology. In: Kapour, B.C. (eds), Fish Adaptation. Sci. Pub. Enfield, U.S.A, p. 203-231.
Hibiya T. 1982. An atlas of Fish Physiology-Normal and Pathological Features Kodansha Ltd. Tokyo, Stuttgart, Gustav Fisher Verlag. 147.
Hodson PV, Blunt BR, Spray DJ. 1978. Chronic toxicity of water borne lead and dietary lead to rainbow trout (Balmo garnderi) in lake Ontario water. Water Research 12, 869-878.
Hu JY, Wang SL, Zhao RC, Yang J, Chen JH, Song L. 2002. Effects of fenvalerate on reproductive and endocrine systems of male rats. Zhonghua nan ke xue 8, 18-21.
Khalesi MK, Abedi Z, Behrouzi S, Kohestan Eskandari S. 2017. Haematological, blood biochemical and histopathological effects of sublethal cadmium and lead concentrations in common carp. Bulgarian Journal of Veterinary Medicine 20(2), 141–150.
Koprucu SS, Koprucu K, Ural MS, Ispir U, Pala M. 2006. Acute toxicity of organophosphorous pesticide diazinon and its effects on behavior and some hematological parameters of fingerling European catfish (Silurus glanis L.). Pesticide Biochemistry and Physiology 86, 99–105. http://dx.doi.org/10.1016/j.pestbp.2006.02.001.
Langard S, Norseth T. 1979. Chromium. In: Friberg L (Ed). Handbook on the toxicology of metals. 2 ed. Amsterdam: Elsevier/North-Holland Biomedical.
Mallesh B, Pandey PK, Kumar K, Vennila A, Kumar S. 2015. Bioconcentration of hexavalent chromium in Cirrhinus mrigala (Ham 1822): effect on haematological parameters. Journal of Biology and Earth Sciences 5(1), 59-67.
Mishra AK, Mohanty B. 2008. Acute toxicity impacts of hexavalent chromium on behavior and histopathology of gill, kidney and liver of the freshwater fish, Channa punctatus (Bloch). Environmental Toxicology and Pharmacology 26, 136- 141.
Mishra S, Srivastava AK. 1980. The acute toxic effects of copper on the blood of a teleost. Ecotoxicology and Environmental Safety 4, 191-194.
Mmereole FUC. 2008. The effects of Replacing Groundnut Cake with Rubber Seed Meal on the Hematologicall and serological indices of broilers. International Journal of Poultry Science 7, 622-624.
Nanda P, Behera MK. 1996. Nickel induced changes in some haemato biochemical parameters of cat fish Heteropneustes fossilis (Bloch.). Environment and Ecology 14, 82–85.
Nimmy MV, Joseph PV. 2018. Impact of lead nitrate on the haematological, biochemical and immunological response of the fresh water fish, Cirrhinus mrigala. Human journals 8(3), 380-400.
Nussey G, Van Vuren JHJ, Du Preez HH. 1995. Effect of copper on the differential white blood cell counts of the Mozambique tilapia (Oreochromis mossambicus). Comparative Biochemistry and Physiology111, 381-388.
Olanike KA. 2007. Haematological Profile of Clarias gariepinus (Burchell, 1822) Exposed to Lead. Turkish Journal of Fisheries and Aquatic Sciences 7, 163-169.
Oliveira Ribeiro CA, Filipak NF. 2006. Haematological findings in neotropical fish Hoplias malabaricus exposed to subchronic and dietary doses of methyl mercury, inorganic lead and tributyltin chloride. Environmental Research 101, 74-80.
Ovuru SS, Ekweozor IKE. 2004. Hematological changes associated with crude oil ingestion in experimental rabbits. African Journal of Biotechnology 3, 346-348.
Pal M, Trivedi SP. 2016. Impact of chromium trioxide on haematological parameters of freshwater fish, Channa punctatus (Bloch). European Journal of Experimental Biology 6(2), 40-42.
Poleo A, Hytterod S. 2003. The effect of aluminium in Atlantic salmon (Salmo salar) with special emphasis on alkaline water. Journal of Inorganic Biochemistry 97, 89–96.
Purves WK, Sadava D, Orians GH, Heller HC. 2004. Life: The Science of Biology (7th Ed.). Sunderland, Mass: Sinauer Associates p 954.
Reynolds M, Peterson E, Quievryn G, Zhitkovich A. 2004. Human nucleotide excision repair efficiently removes chromium-DNA phosphate adducts and protects cells against chromate toxicity. Journal of Biological Chemistry 279(29), 30419-24.
Sandeep V, Praveena M, Kavitha N, Jayantha Rao K. 2013. Impact of Tannery Effluent, Chromium on Hematological Parameters in a Fresh water Fish, Labeo rohita (Hamilton). Journal of Research Animal, Veterinary and Fishery Sciences 1(6), 1-5.
Safahieh A, Hedyati A, Savari A, Movahedinia A. 2010. Experimental approaches of hematotoxic and immunotoxic effects of mercury chloride on yellowfin sea bream (Acanthopagrus latus). American-Eurasian Journal of Toxicological Sciences 2(3), 169-176.
Shah SL. 2006. Hematological parameters in tench Tinca tinca after short term exposure to lead. Journal of Applied Toxicology 26, 223-228. http://dx.doi.org/10.1002/jat.1129
Shalaby AM. 2001. Protective effect of Ascorbic acid against Mercury intoxication in Nile tilapia (Oreochromis niloticus). Journal of Egyptian Academic Society for Environmental Development (D Environmental studies) 2(3), 79 – 97.
Sharma J, Langer S. 2014. Effect of Manganese on haematological parameters of fish, Garra gotyla gotyla. Journal of Entomology and Zoology Studies 2(3), 77-81.
Shariati M, Noorafshan A, Mokhtari M, Askari HR. 2008. The effects of trifluralin on LH, FSH and testosterone levels and testis histological changes in adult rats. International Journal of Fertility and Sterility 2, 23-28.
Shuhaimi-Othman MY, Nadzifah AK, Ahmad. 2010. Toxicity of Copper and Cadmium to Freshwater Fishes. World Academy of Science, Engineering and Technology 65, 869-871.
Sifakis S, Mparmpas M, Soldin OP, Tsatsakis A. 2011. Pesticide Exposure and Health Related Issues in Male and Female Reproductive System, Pesticides-Formulations, Effects, Fate, Prof. Margarita Stoytcheva (Ed.), ISBN: 978-953-307-532-7, In Tech.
Sinha AK, Sinha MK, Adhikari S. 2000. Effect of the copper toxicity on haematological profile of Indian major carp Labeo rohita. Hand book Industry Environment and Pollution 166-172.
Singh D, Nath K,Trivedi SP, Sharma YK. 2008. Impact of copper on haematological profile of fresh water fish, Channa punctatus. Journal of Environmental Biology 29(2), 253-257.
Sudhasaravanan R, Binukumari S. 2015. Impact of electroplating industrial effluent on the hematology of the fish catla catla. International Journal of Recent Advances in Multidisciplinary Research 2(9), 0723-0726.
Tavares-Dias M, De Moraes FR. 2007. Leukocyte and thrombocyte reference values for channel catfish (Ictalurus punctatus Raf.), with an assessment of morphological, cytochemical, and ultrastructural features. Veterinay Clinical Pathology 36, 49-54.
Thangam Y, Umavathi S, Vysakh VB. 2016. Investigation of mercury toxicity in haematological.
Witeska M. 2005. Stress in fish. Hematological and Immunological effects of heavy metals, Electronic Journal of Ichthyology 1, 35-41.
Vutukuru S. 2005. Acute effects of hexavalent chromium on survival, oxygen consumption, hematological parameters and some biochemical profiles of the Indian major carp, Labeo rohita. International Journal of Environmental Research and Public Health 2(3), 456-62.
Yang H, Rose NL. 2003. Distribution of Hg in the lake sediments across the UK. Science of the Total Environment 304, 391-404.
Sonia Aslam, Ali Muhammad Yousafzai, Hameed Ur Rehman (2019), Toxicological impact of hexavalent chromium on hematology and FSH, LH hormones of Ctenopharyngodon idella; IJB, V15, N5, November, P121-129
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