Toxicological impact of hexavalent chromium on hematology and FSH, LH hormones of Ctenopharyngodon idella

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Toxicological impact of hexavalent chromium on hematology and FSH, LH hormones of Ctenopharyngodon idella

Sonia Aslam, Ali Muhammad Yousafzai, Hameed Ur Rehman
Int. J. Biosci.15( 5), 121-129, November 2019.
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Heavy metal chromium influences the nutritive value of fish. The aim of this study is to scrutinize the effect of sub lethal dose of Cr (VI) on hematological parameters and endocrine hormones FSH and LH in the widely consumed fresh water fish Ctenopharyngodonidella. For this purpose, the experiment was designed to expose the fish to sublethal dose of hexavalent chromium (120 mg/l) for 7 days. After the stipulated time period blood was collected for hematological and hormonal studies and analysed through routine clinical methods. The results indicated a consistent reduction compared to control in the values of white blood cells (14.75%), hemoglobin (1.08%), red blood cells (11.11%), platelets (48.92%), platelet distribution width (6.76%), mean platelet volume (2.24%) and plateletcrit (46.35%). While increasing trend was noticed in hematocrit (59.17%), Mean corpuscular volume (3708.96%), Mean corpuscular hemoglobin (343.42%), Mean corpuscular hemoglobin concentration (96.48%). Among hormones follicle stimulating hormone and luteinizing hormone represented a non-significant elevation of 63.74% and 40.73%. Reduction of blood parameters represents severe hemolysis, anemic condition and retarded fish health. While increasing trend indicates activation of immune system against the Cr (VI) stress. Cr induced reproductive disruption by increasing level of FSH and LH.


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