Why Brine shrimp (Artemia salina) larvae is used as a screening system for nanomaterials? The science of procedure and nano-toxicology: A review

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Why Brine shrimp (Artemia salina) larvae is used as a screening system for nanomaterials? The science of procedure and nano-toxicology: A review

Wali Muhammad, Naimat Ullah, Mehmand Khan, Waqar Ahmad, Muhammad Qasim Khan, Bilal Haider Abbasi
Int. J. Biosci.14( 5), 156-176, May 2019.
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Numerous creative key innovations in the field of nanotechnology have turned the minds of scientists to explore new possibilities in diagnosis and treatment of incipient diseases. Nanotoxicity, the sector of vigorous research, has emerged the increased use of nanoparticles mainly in commercially available products. The risk factors of nanomaterials are still unknown. For this purpose, extensive procedures were used to carry out the toxic effects of these nanomaterials. Recently, many researchers have focused on brine shrimp lethality assay owing to their low cost, convenience, and rapid screening procedure. The species of Brine shrimp, Artemia salina is commonly used nowadays in drug discovery to screen the toxic effect of different components. The current review article is focused to elucidate the cytotoxic approach of nanomaterials towards Brine shrimp (Artemia salina), their mechanistic perspective, procedure and why scientists use it as a screening system with possible future prospects.


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