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Prevalence of HBV, HCV, HIV and syphilis in blood donor at Mardan Medical complex, Khyber Pakhtunkhwa, Pakistan

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Research Paper 01/05/2018
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Prevalence of HBV, HCV, HIV and syphilis in blood donor at Mardan Medical complex, Khyber Pakhtunkhwa, Pakistan

Muhammad Zeeshan, Faheem Anwar, Iftikhar Ali Shah, Muzamil Shah
Int. J. Biosci.12( 5), 295-301, May 2018.
Certificate: IJB 2018 [Generate Certificate]
Key: Blood groupHBV and VDRLHCVHIVPrevalence

Abstract

The current study was valued to find the incidence of Hepatitis B, Hepatitis C, VDRL (venereal Disease Research Laboratory) and HIV in the healthy blood donors of Mardan and its neighboring districts of KPK in the period from December 2017 to 2018. A total of 4552 blood donor’s samples were screened through ELISA kit (ARCHITECT i1000SR automated immunoassay analyzer chemiluminescent microparticle immunoassay). In total 4552 blood donor’s HIV, occurrence was 0.04%, (2/4552), HBV occurrence was a little higher than 1.31%, (60/4552), VDRL occurrence was recorded in the range of 0.63%, (29/4552), while HCV was limited to the value of 1.2%, (54/4552). The current study also exposed the spreading design of HIV, HBV, HCV and VDRL in the blood groups of responsive samples. Blood group O+ was holding the peak incidence value i.e. HCV 29.62% (16/54), HBV 33.33% (20/60), HIV 50% (1/2), VDRL 34.48% (10/29). Shadowed by A+ 16.66 (9/54), HBV 20% (12/60), HIV 0% (0/2), VDRL 20.68% (6/29). And B+ was holding values in HCV 11.11% (6/54), HBV 15% (9/54), HIV was not noted in this regard, while VDRL is 30.76% (8/29). These statistics outcomes recommend uncertain degree of occurrence, still a much wide seroprevalence analysis of the over-all population are required to find the correct occurrence.

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Abbas Z, Shazi L, Jafri W. 2005. Prevalence of hepatitis B in individuals screened during a countrywide campaign in Pakistan. Liver International 25(6), 1333-1334.

Adjei AA, Kudzi W, Armah H, Adiku T, Amoah AB, Ansah J. 2003. Prevalence of antibodies to syphilis among blood donors in Accra, Ghana. Japanese Journal of Infectious Diseases 56(4), 165-167.

Ahmed F, Shah SH, Tariq M, Khan JA. 2000. Prevalence of hepatitis B carrier and HIV in healthy blood donors at Ayub Teaching Hospital. Pak J Med Res 39(2), 91-2.

Ali SA, Donahue RM, Qureshi H, Vermund SH. 2009. Hepatitis B and hepatitis C in Pakistan: prevalence and risk factors. International Journal of Infectious Diseases 13(1), 9-19.

Allen V G, Mitterni L, Seah C, Rebbapragada A., Martin IE, Lee C, Low DE. 2013. Neisseria gonorrhoeae treatment failure and susceptibility to cefixime in Toronto, Canada. Jama 309(2), 163-170.

Ayele W, Nokes DJ, Abebe A, Messele T, Dejene A, Enquselassie F, Fontanet al. 2002. Higher prevalence of anti‐HCV antibodies among HIV‐positive compared to HIV‐negative inhabitants of Addis Ababa, Ethiopia. Journal of Medical Virology 68(1), 12-17.

Bloch EM, Vermeulen M, Murphy E. 2012. Blood transfusion safety in Africa: a literature review of infectious disease and organizational challenges. Transfusion Medicine Reviews 26(2), 164-180.

Butsashvili M, Tsertsvadze T, McNutt LA, Kamkamidze G, Gvetadze R, & Badridze N. 2001. Prevalence of hepatitis B, hepatitis C, syphilis and HIV in Georgian blood donors. European Journal of Epidemiology 17(7), 693-695.

Chikwem JO, Mohammed I, Okara GC, Ukwandu NC, Ola TO. 1997. Prevalence of transmissible blood infections among blood donors at the University of Maiducuri Teaching Hospital, Maiduguri, Nigeria. East African Medical Journal 74(4), 213-216.

Jeremiah ZA, Koate B, Buseri F, & Emelike F. 2008. Prevalence of antibodies to hepatitis C virus in apparently healthy Port Harcourt blood donors and association with blood groups and other risk indicators. Blood Transfusion 6(3), 150.

Lange B, Cohn J, Roberts T, Camp J, Chauffour J, Gummadi N, Pichler C. 2017. Diagnostic accuracy of serological diagnosis of hepatitis C and B using dried blood spot samples (DBS): two systematic reviews and meta-analyses. BMC Infectious Diseases 17(1), 700.

Liumbruno GM, Liumbruno, C, Rafanelli D. 2011. Intraoperative cell salvage in obstetrics: is it a real therapeutic option. Transfusion 51(10), 2244-2256.

Matee MI, Magesa PM, Lyamuya EF. 2006. Seroprevalence of human immunodeficiency virus, hepatitis B and C viruses and syphilis infections among blood donors at the Muhimbili National Hospital in Dares Salaam, Tanzania. BMC Public Health 6(1), 21.

Mehr MT, Khan H, Nisa QU, Iman NU. 2013. Frequency of hepatitis B & C infection in newly recruited civil servants in Khyber Pakhtunkhwa. Khyber Medical University Journal 5(2).

Okoroiwu HU, Okafor IM, Asemota EA, Okpokam DC. 2018. Seroprevalence of transfusion-transmissible infections (HBV, HCV, syphilis and HIV) among prospective blood donors in a tertiary health care facility in Calabar, Nigeria; an eleven years evaluation. BMC Public Health 18(1), 645.

ÖNER S, YAPICI G, ŞAŞMAZ CT, KURT AÖ, BUĞDAYCI R. 2011. Hepatitis B, hepatitis C, HIV, and VDRL seroprevalence of blood donors in Mersin, Turkey. Turkish Journal of Medical Sciences 41(2), 335-341.

Patton GC, Coffey C, Sawyer SM, Viner RM, Haller DM, Bose K, Mathers CD. 2009. Global patterns of mortality in young people: a systematic analysis of population health data. The lancet 374(9693), 881-892.

Razavi-Shearer D, Gamkrelidze I, Nguyen MH, Chen DS, Van Damme P, Abbas Z, Akarca U. 2018. Global prevalence, treatment, and prevention of hepatitis B virus infection in 2016: a modelling study. The Lancet Gastroenterology & Hepatology 3(6), 383-403.

Sallam TA, Tong CYW, Cuevas LE, Raja’a YA, Othman AM, Al-Kharsa KR. 2003. Prevalence of blood-borne viral hepatitis in different communities in Yemen. Epidemiology & Infection 131(1), 771-775.

Sawke N, Sawke GK. Chawla S. 2010. Seroprevalence of common transfusion-transmitted infections among blood donors.

Sayal SK, Das AL, Nema SK. 1996. Study of blood groups in HIV seropositive patients. Indian Journal of Dermatology, Venereology and Leprology 62(5), 295.

Shah SZ, Qureshi A, Rizwan M, Bilal M, Khattak MHR, Gul U, Ahmad A. 2015. Sero-Prevalence of HCV and HIV antibodies among different groups of general population of Peshawar Cantonment, KPK, Pakistan.

Shamsul AQ, Shamsa A, Muhammad A, Syed IA, Aqeel A. 2000. Detection of hepatitis B viruses in normal individuals of Karachi. JCPSP, Journal of the College of Physicians and Surgeons Pakistan 10(12), 467-469.

Sheikh AA, Sheikh AS, Sheikh NS, Malik MT, Afridi F. 2004. High frequency of false positive results in HIV screening in blood banks. Journal of Ayub Medical College, Abbottabad: JAMC 16(1), 28-31.

Siddiqui TS, Lahrasab W, Sharif MA. 2012. Prevalence of hepatitis B and C in healthy adult males of paramilitary personnel in Punjab. Journal of Ayub Medical College Abbottabad 24(3-4), 138-140.

Sultan F, Mehmood T, Mahmood MT. 2007. Infectious pathogens in volunteer and replacement blood donors in Pakistan: a ten-year experience. International Journal of Infectious Diseases 11(5), 407-412.

Tarantola DJ, Mann JM. 1996. Global expansion of HIV infection and AIDS. Hospital Practice 31(10), 63-79.

Tessema B, Yismaw G, Kassu A, Amsalu A, Mulu A, Emmrich, F, Sack U. 2010. Seroprevalence of HIV, HBV, HCV and syphilis infections among blood donors at Gondar University Teaching Hospital, Northwest Ethiopia: declining trends over a period of five years. BMC infectious diseases 10(1), 111.

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