home icon user icon
Welcome to International Network for Natural Sciences | INNS Pub.
Home My Account
Submit Manuscript
double_slash
breadcumb_bg

Clinical Validity of Deep Brain Stimulation (DBS) and Gamma Knife Thalamotomy (GKT) Neurosurgical Therapeutic Techniques Treating Neurogenic Disorders

Paper Details

Research Paper 01/05/2020
Views (415) Download (20)
current_issue_feature_image
publication_file

Clinical Validity of Deep Brain Stimulation (DBS) and Gamma Knife Thalamotomy (GKT) Neurosurgical Therapeutic Techniques Treating Neurogenic Disorders

Joe Payyapilly Joseph, Thomas Sebastian, Zubair Ahmed Yousfani, Naeem Bukhari, Muhammad Adeeb Khan, Nazia Akbar, Amina Arif
Int. J. Biosci.16( 5), 167-177, May 2020.
Certificate: IJB 2020 [Generate Certificate]
Key: Brain stimulationThalamotomyTherapeutic Techniques

Abstract

Increased progression of neurogenic disorders among elderly personnel is considered a top trend challenge for developed economies to standardize the life quality. Generally, Deep brain stimulation (an invasive neurosurgical technique) and Gamma Knife Thalamotomy (non-invasive radiosurgical therapeutic technique) are adopted to treat neurogenic disorders. Deep brain stimulation includes implantation of receptor compatible electrical devices in human brain, to generate type specific electrical signals to improve the impulse conduction capability of a motor neuron. Whereas, Gamma knife thalamotomy is adopted to target tumor specific cells by radiations to inhibit tumor genesis. Selection of either technique treating specific patient is considered is a key challenge faced by many neurosurgeons. Current study aims to evaluate the clinical validity and relative specificity of deep brain stimulation and gamma knife thalamotomy treating neurogenic disorders. NCBI/PubMed, Medline and neurosurgery Journal databases were retrieved from January 2008-upto November 2018. About 39 principle studies with complete demographic details were assessed and analyzed by using RISMA and Revman5.30 multiple tools. About 6, 724 patients from past ten years were enrolled. By following random effect data analysis tool at 95 % confidence interval moderate target specificity was observed for both techniques (heterogeneity Tau2 = 0.76; Chi2 = 8.08, I2 = 63 %). Whereas relative target specificity of DBS was recorded higher rather than GKT. Similarly, GKT was found safer in comparison to DBS. Calculated Risk ratio = 2.20 further assure the validity of both neurosurgical techniques. Even not a single neurosurgical therapeutic technique was found effective against inherited neurological disorders.

VIEWS 18
Cover PDF

Alexander S, Taghva DA, Malone Ali RR. 2013. Deep Brain Stimulation for Treatment-Resistant Depression. World Neurosurgery (80), 3-4.

Alomar S, King NK, Tam J, Bari AA, Hamani C, Lozano AM. 2017. Speech and language adverse effects after thalamotomy and deep brain stimulation in patients with movement disorders: A meta‐analysis. Movement Disorder 32, 53-63. http://dx.doi.org/10.1002/mds.26924.

Arranz MJ, Kerwin RW. 2003. Advances in the pharmacogenetic prediction of antipsychotic response. Toxicology 192, 33-35.

Blomstedt Patric. 2011. Influence of age, gender and severity of tremor on outcome after thalamic and subthalamic DBS for essential tremor Parkinsonism & Related Disorders 17(8), 617-620.

Cho KR, Kim HR, Im YS, Youn J, Cho JW, Lee JI. 2015. The outcome of gamma knife thalamotomy in patients with an intractable tremor. Journal of Korean Neurosurgical Society 57(3), 192-6.

Chopra A, Klassen BT, Stead M. 2013. Current clinical application of deep-brain stimulation for essential tremor. Neuropsychiatric disease and treatment 9, 1859-65.

Dembek TA, Barbe MT, Åström M, Hoevels M, Visser-Vandewalle V, Fink GR, Timmermann L. 2016. Probabilistic mapping of deep brain stimulation effects in essential tremor. Neuro Image Clinical 13, 164-173.

Deuschl G, Schade-Brittinger C, Krack P. 2006. A randomized trial of deep-brain stimulation for Parkinson’s disease. New England Journal of Medicine 355, 896-908.

Deuschl G. 2011. Treatment of patients with essential tremor. The Lancet Neurology 10(2), 148-161.

Deuschl G. 2013. New hope for severe essential tremor. The Lancet Neurology 12(5), 420-422.

Elaimy AL, Demakas JJ, Mackay AR, Lamoreaux WT, Fairbanks RK. 2011. Clinical Outcomes of Gamma Knife Radiosurgery in the Treatment of Patients with Tremors. Journal of Stem Cell Research Therapy 4, 001. http://dx.doi.org/10.4172/2157-7633.S4-001.

Etienne M, Holl, Erika A, Petersen, Thomas Foltynie, Irene Martinez-Torres, Patricia Limousin, Marwan I, Hariz, Ludvic Zrinzo. 2010. Improving Targeting in Image-Guided Frame- Based Deep Brain Stimulation, Operative Neurosurgery 67(2), 437-447.

Farrer M, Gwinn-Hardy K, Hutton M, Hardy J. 1999. The genetics of disorders with synuclein pathology and Parkinsonism. Human Molecular Genetics 8, 1901-1905.

Follett A, Kenneth, Weaver, Frances, Stern, Matthew, Hur, Kwan. 2010. Pallidal versus Subthalamic Deep-Brain Stimulation for Parkinson’s Disease. New England Journal of Medicine 362(22), 2077-2091. http://dx.doi.org/10.1056/nejmoa0907083

Fox MW, Ahlskog JE, Kelly PJ. 1991. Stereotactic ventrolateral is thalamotomy for medically refractory tremor in post-levodopa era Parkinson’s disease patients. Journal of Neurosurgery 75, 723-730.

Franzini A, Broggi G, Cordella R, Dones I, Messina G. 2013. Deep-brain stimulation for aggressive and disruptive behavior. World Neurosurgery 80(3–4), 11-14.

Gooch CL, Pracht E, Borenstein AR. 2017. The burden of neurological disease in the United States: A summary report and call to action. Annals of Neurology 81(4), 479-484.

Greenberg BD, Gabriels LA, Malone DA, Rezai AR, Friehs GM, Okun MS, Shapira NA. 2008. Deep brain stimulation of the ventral internal capsule/ventral striatum for obsessive-compulsive disorder: worldwide experience. Molecular Psychiatry 15(1), 64-79.

Greenberg BD, Rauch SL, Haber SN. 2009. Invasive circuitry-based neurotherapeutics: stereotactic ablation and deep brain stimulation for OCD. Neuropsychopharmacology 35(1), 317-36.

Günther D. 2011. From mathematics to movement disorders Williams, Ruth. The Lancet Neurology 10(2), 118.

Hariz G, Blomstedt P, Koskinen LD. 2008. Long‐term effect of deep brain stimulation for essential tremor on activities of daily living and health‐related quality of life. Acta Neurologica Scandinavica 118, 387- 394. http://dx.doi.org/10.1111/j.1600-0404.2008.01065.x.

Hedera P. 2014. Treatment of Wilson’s disease motor complications with deep brain stimulation. Annals of New York Academy of Sciences 1315, 16-

Hemmings W, Pieter JVDL, Remco S, Kris VKLG, Guozhen L, Guihua P, Yongchao L, Dianyou L, Shikun Z, Bomin S, Bart N. 2013. Deep-Brain Stimulation for Anorexia Nervosa, World Neurosurgery 80(3-4), (1-10).

Higuchi Y, Matsuda S, Serizawa T. 2017. Gamma knife radiosurgery in movement disorders: Indications and limitations. Movement Disorders 32, 28-35.

Holslag, Joost, Neef, Nienke, Beudel, Martijn, Drost, Gea, Oterdoom DI, Kremer, Naomi, Van Laar, Teus Van Dijk J, Marc C. 2017. Deep Brain Stimulation for Essential Tremor: A Comparison of Targets. World Neurosurgery 110, 580-584.

Koller WC, Lyons KE, Wilkinson SB, Troster AI, Pahwa R. 2001. Long-term safety and efficacy of unilateral deep brain stimulation of the thalamus in essential tremor. Movement Disorders 16, 464-468.

Kondziolka D, Lunsford LD, Witt TC, Flickinger JC. 2000. The future of radiosurgery: radiobiology, technology, and applications. Surgical Neurology 54, 406-414.

Laxton AW, Lozano AM. 2013. Deep brain stimulation for the treatment of Alzheimer disease and dementia. World neurosurgery 80(3-4), 1-8.

Lee JY, Kondziolka D. 2005. Thalamic deep brain stimulation for management of essential tremor. Journal of Neurosurgery 103, 400-403.

Lim S, Hodaie M, Fallis M, Poon Y, Mazzella F, Moro E. 2010. Gamma Knife Thalamotomy for Disabling Tremor Blinded Evaluation. Archives of Neurology 67(5), 584-588.

Louis ED, Ottman R, Hauser WA. 1998. How common is the most common adult movement disorder? Estimates of the prevalence of essential tremor throughout the world. Movement Disorders 13, 5-10.

Lozano A, Levy R. 2012. Reoperation of Deep Brain Stimulation in Patients with Essential Tremor. World neurosurgery 78(5), 442-444.

Mark K. 2011. Deep brain stimulation: current and future clinical applications. Mayo Clinic Proceedings 86(7), 662-72.

Mehanna R, Machado AG, Oravivattanakul S, Genc G, Cooper SE. 2014. Comparing Two Deep Brain Stimulation Leads to One in Refractory Tremor. The Cerebellum 13(4), 425-432.

Michael T. Barbe LL, Matthias R, Janina D, Esther F, Lars W, Alfons S, Niels A, Volker S, Gereon RF, Mohammad M, Lars T. 2011. Deep brain stimulation of the ventral intermediate nucleus in patients with essential tremor: Stimulation below the intercommissural line is more efficient but equally effective as stimulation above. Experimental Neurology 230(1), 131-137.

Pantaleo R, Pasquale S, Manlio B, Giangennaro C, David JA. 2012. Non-respective surgery and radiosurgery for treatment of drug resistant epilepsy, Epilepsy Research 99(3), 193-201.

Parvizi J, Le S, Foster BL, Bourgeois B, Riviello J, Prenger E, Saper C, Kerrigan JF. 2011. Gelastic epilepsy and hypothalamic hamartomas: neuroanatomical analysis of brain lesions in 100 patients. Brain: a journal of neurology 134(10), 2960-8.

Patrick P, Antonio AF, De S, Alessandra G, Eric, David McArthur, Ausaf Bari B. 2011. The accuracy of Frame-Based Stereotactic Magnetic Resonance Imaging vs. Frame-Based Stereotactic Head Computed Tomography Fused With Recent Magnetic Resonance Imaging for Postimplantation Deep Brain Stimulator Lead Localization, Neurosurgery 69(6), 1299-1306.

Ravikumar Vk, Parker JJ, Hornbeck TS, Santini VE, Pauly KB, Wintermark M, Ghanouni P, Stein SC, Halpern CH. 2017. Cost‐effectiveness of focused ultrasound, radiosurgery and DBS for essential tremor. Movement Disorders 32, 1165-1173.

Shabbir HI. 2018. Letter to the Editor. Clinical Neurophysiology 129, 2217-2218.

Stéphan C, Mircea P, Paul K, Julien B, Alexandre K, Olivier D, Thierry B, Alim LB. 2013. Deep Brain Stimulation for Obsessive- Compulsive Disorder: Subthalamic Nucleus Target, World Neurosurgery 80(3-4), 1-8.

Steven MF, Ashwini S, Beverly ASR, Carl S, Patricia S, Elisabeth JVB. 2011. An Evaluation of Neuroplasticity and Behavior After Deep Brain Stimulation of the Nucleus Accumbens in an Animal Model of Depression. Neurosurgery, 69(6), 1281-1290.

Sveinbjornsdottir S, Hicks AA, Jonsson T. 2000. Familial aggregation of Parkinson’s disease in Iceland. New England Journal of Medicine 343, 1765-1770.

Takamitsu Y, Yoichi K, Toshiki O, Kazutaka K, Hideki O, Chikashi F. 2013. Deep Brain Stimulation and Spinal Cord Stimulation for Vegetative State and Minimally Conscious State, World Neurosurgery 80(3-4), 1-9.

Terao T, Yokochi F, Taniguchi M, Kawasaki T, Okiyama R, Hamada I, Takahashi H. 2008. Microelectrode findings and topographic reorganisation of kinaesthetic cells after gamma knife thalamotomy. Acta Neurochirurgica 150(8), 823- 827. http://dx.doi.org/10.1007/s00701-008-1606-x

Tuleasca C, Pralong E, Najdenovska E, Cuadra MB, Marques JR, Vingerhoets FJ, Régis J, Bloch J, Levivier M. 2017. Deep brain stimulation after previous gamma knife thalamotomy of the Vim for essential tremor is feasible! Clinical, electrophysiological and radiological findings. Acta Neurochirurgica 159, 1371-1373.

Voges Juergen, Müller, Ulf, Bogerts, Bernhard, Münte, Thomas, Heinze, Hans- Jochen. 2012. Deep Brain Stimulation Surgery for Alcohol Addiction. World neurosurgery 80(3-4), 21- 31. http://dx.doi.org/10.1016/j.wneu.2012.07.011

Weaver FM, Follett K, Stern M. 2009. Bilateral deep brain stimulation vs. best medical therapy for patients with advanced Parkinson disease: a randomized controlled trial. The Journal of the American Medical Association 301, 63-73.

Witjas T, Carron R, Boutin R, Eusebio A, Azulay JP, Régis J. 2016. Essential tremor: Update of therapeutic strategies (medical treatment and gamma knife thalamotomy), Revue Neurologique 172(8-9), 408-415.

Young RF, Li F, Vermeulen S, Meier R. 2010. Gamma Knife thalamotomy for treatment of essential tremor: long-term results. Journal of Neurosurgery 112(6), 1311-1317.

Submit Manuscript