An exposure study of endocrine disruptors on haematology of fresh water fish Labeo rohita

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Research Paper 01/02/2018
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An exposure study of endocrine disruptors on haematology of fresh water fish Labeo rohita

Misbah Rashid, Ghazala Jabeen, Sofia Nosheen
Int. J. Biosci. 12(2), 136-140, February 2018.
Copyright Statement: Copyright 2018; The Author(s).
License: CC BY-NC 4.0

Abstract

Synthetic chemicals released in water bodies resulting in exposure to fresh water organisms and enter in food chain. Phthalates and parabens are those chemicals now being studied for their endocrine disrupting potentials. This study was designed to determine the haematological effects of phthalate, parabens and their mixtures on fresh water and commonly eaten fish Labeo rohita. To healthy fish (Labeo rohita) of juvenile age, experimental dose of ester of phthalate, paraben and their mixture were given as treatment group for 30 days. Haematological parameters were studied. A significant fluctuation was seen in erythrocytes (0.025+0.005), packed cell volume (0.15+0.05), haemoglobin (0.3+0.1*), platelets (12 + 2*), mean corpuscular haemoglobin (726.5+623.5), and mean corpuscular haemoglobin concentration (7050+6950) as compared to control. Dimethyl phthalate (DMP) and dibutyl phthalate (DBP) treated fish showed a statically significant decrease in erythrocytes (0.025+0.005*; 0.08+0.07*) and platelets (12 + 2*; 71+1.5*) as compared to fish of other groups. Fluctuations in blood parameters may lead to further abnormalities in an organism.

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