Antibacterial activity of Azadirachta indica and Citrullus colocynthis against different microorganisms

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Research Paper 01/06/2018
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Antibacterial activity of Azadirachta indica and Citrullus colocynthis against different microorganisms

Muhammad Usman Akbar, Saadullahkhattak, Umair Ali khan Saddozai, Rafiq Ahmad, Muhammad Badar, Shams- uz- Zaman, Muhammad Daud, Ikram Ali, Waqar Ahmad
Int. J. Biosci.12( 6), 85-90, June 2018.
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Multiple bacterial infections are significantly increasing with passage of time, which contributing to rate of morbidity and mortality. Frequent use of drug making bacteria resistant therefore search of new drugs with fewer side effects become an urgent necessity. The purpose of this work was to evaluate the antibacterial activity of Azadirachta indica and Citrullus colocynthis against different Microorganisms. The work was carried out in the Gomal Center of Biochemistry and Biotechnology Gomal University, D. I. Khan Khyber Pakhtunkhwa, Pakistan during the month of July 2017. The Methanolic extracts were used by agar well diffusion method and activity was measured through zone of inhibtions. According to the result methanolic extract inhibited the growth of E. coli, Klebsiella pneumonia and S. Aurous. Between two medicinal plants, Citrullus colocynthis was found more effective. Mininum Inhibitory concentrations of these both plants extracts against bacterial strains were good. Similar to agar well diffusion Citrullus was also found to more effective in MIC. It was concluded that methanolic extract of these plants have antibacterial activity.


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