Antimicrobial and antioxidant properties of silver nanoparticles from Moringa oleifera gum: a green synthesis approach
Paper Details
Antimicrobial and antioxidant properties of silver nanoparticles from Moringa oleifera gum: a green synthesis approach
Abstract
Plant gums have enormous medicinal potential and have been used in the pharmaceutical and biomedical fields. In the present investigation, Moringa oleifera gum (MOG) was collected, and its physical properties and phytochemical composition were investigated. Silver nanoparticles (AgNPs) were produced, and characterization was carried out using UV spectroscopic analysis and scanning electron microscopy (SEM). In this study, the standard method was used for the antioxidant assay and the antimicrobial test. The synthesized nanoparticles (NPs) have irregular shapes and no fixed geometry. The agglomerate shape resembles that of pebble-like structures. UV‒vis analysis proved the wavelength of the sample to be 350–470 nm. In antioxidant studies, the synthesized AgNPs exhibited significant DPPH radical scavenging activity values ranging from 21.15 ± 0.017 to 63.46± 0.03 g/mL at concentrations ranging from 100 to 500 g/mL. In an antimicrobial experiment, the maximum incubation zone was 18 mm by 100 µL of AgNPs synthesized from M. oleifera gum extract against S. typhi. P. aeruginosa expressed a 16 mm zone of incubation at 100 µL of AgNPs synthesized from M. oleifera gum. According to the findings of this study, AgNPs derived from M. oleifera gum can be employed as a lead chemical in the creation of an effective antimicrobial drug for the treatment of microbial infections. This research establishes the foundation for synthesizing AgNPs from M. oleifera gum and its powerful novel pharmacological applications.
Zaigham H, Tauheed A, Ali A. 2019. Recent trend in traditional medicine dosage form and present status of Unani and Ayurvedic Medicine. International Journal of Pharmaceutical Sciences and Research 10(4), 1640-1649.
Flora SJS, Pachauri V. 2011.Moringa (Moringaoleifera) seed extract and the prevention of oxidative stress. In: Preedy, VR, Watson, RR, Patel, VB. (Eds.), Nuts and Seeds in Health and Disease Prevention. Academic Press, San Diego 92, 775–785.
Fahey JW. 2005. Moringa oleifera: A Review of the Medical Evidence for Its Nutritional, Therapeutic, and Prophylactic Properties. Part 1. Trees Life J 1, 15.
Maheshwari K, Yadav RK, Malhotra J, Dhawan NG, Mohan L. 2014. Fascinating Nutritional, Prophylactic, Therapeutic and Socio-Economic Reconcile Attributable to Drum Stick Tree (Moringa oleifera Lam.). Global journal of medical research. Pharma, Drug Discovery, Toxicology & Medicine 14, 11-22.
Mehta J, Shukla A, Bukhariya V, Charde R, 2011. The Magic Remedy of Moringaoliferia: An Overview. International Journal of Biomedical and advance research 2, 215-227.
Farokhzad OC, Cheng JJ, Teply BA, Sherifi I, Jon S, Kantoff PW, Richie JP, Langer R. 2006. Targeted nanoparticle aptamerbioconjugates for cancer chemotherapy in vivo. Proceedings of the National Academy of Sciences of the United States of America 103, 6315–6320.
Araujo M, Moises das Virgens Santana, Antonio do Nascimento Cavalcante, Livio Cesar Cunha Nunes, Luiz Carlos Bertolino, Carla Adriana Rodrigues de Sousa Brito, Humberto Medeiros Barreto, Carla Eiras. 2020. Cashew-gum-based silver nanoparticles and palygorskite as green nanocomposites for antibacterial applications. Materials Science & Engineering C. 115, 110927.
Gupta S, Rohit J, Kachhwaha S, Kothari SL. 2018. Nutritional and medicinal applications of Moringa oleifera Lam.—Review of current status and future possibilities. Journal of Herbal Medicine 11, 1-11.
Kumar RS, Renuka R. 2019. Isolation and Characterization of Moringa olifera Gum: A Novel Sustained Release Polymer. Journal of Drug Delivery & Therapeutics 9(3), 484-486.
Jarald EE, Sharma Sumati, Sheeja Edwin, Ahmad S, Patni S, Daud A. 2012. Characterization of Moringa oleifera Lam. Gum to establish it as a Pharmaceutical Excipient. Indian Journal of Pharmaceutical Education and Research 46(3).
Harborne JB. 1998. Textbook of Phytochemical Methods. A Guide to Modern Techniques of Plant Analysis. 5th Edition, Chapman and Hall Ltd, London 21, 72.
Kokate CK. 2005. Pharmacognosy” edition thirtieth published by Nirali Prakashan Pune 181, 186.
Shanmugavel G, Prabakaran K, George. 2018. B Evaluation of phytochemical constituents of Moringa oleifera (lam.) Leaves collected from Puducherry region, South India, International Journal of Zoology and Applied Biosciences 3(1).
Chrzczanowicz J, Gawron A, Zwolinska A, de Graft-Johnson J, Krajewski W, Krol M, Markowski J, Kostka T, Nowak D. 2008. Simple method for determining human serum 2, 2-diphenyl-1-picryl-hydrazyl (DPPH) radical scavenging activity–possible application in clinical studies on dietary antioxidants. Clinical Chemical Laboratory Medicine 46(3), 342-349 p.
Narenkumar J, Parthipan P, Madhavan J, Murugan K, Marpu SB, Suresh AK, Rajasekar A. 2018. Bioengineered silver nanoparticles as potent anti-corrosive inhibitor for mild steel in cooling towers. Environmental Science and Pollution Research 25(6), 5412-5420 p.
Panda D, Si S, Swain S, Kanungo SK, Gupta R. 2006. Preparation and evaluation of gels from the gum of Moringa oleifera. Indian Journal of Pharmaceutical Sciences 68(6), 777780.
M Dekker. 2002. “Edward MR: Modern Pharmaceutics”. New York. 287, 298.
Nep EI, Conway BR. 2010. Characterization of Grewia gum, a potential pharmaceutical excipient. Journal of Excipients and Food Chemicals 1, 30–40.
Somboonpanyakul P, Wang Q, Cui W, Barbut S, Jantawat P. 2006.Malva nut gum.(Part I): Extraction and physicochemical characterization. Carbohydr. Polym 64, 247–253.
Vinod VTP, Sashidhar RB, Suresh K I, Rao B R, Saradhi UVR, Rao TP. 2008. Morphological, Physico-chemical and structural characterization of gum kondagogu (Cochlospermumgossypium): A tree gum from India. Food Hydrocolloids 22, 899–915.
Nussinovitch A. 2009. Plant gum exudates of the world: sources, distribution, properties, and applications. CRC Press. http://dx.doi.org/10.1201/9781420052244.
Mohammed FAA. 2015. Antioxidants composition of moringa (Moringa oleifera lam) in different plant organs (Doctoral dissertation).
Abdulkarim SM, Long K, Lai OM, Muhammad SKS, Ghazali HM. 2005. Some Physico-chemical properties of Moringa oleifera seed oil extracted using solvent and aqueous enzymatic methods, Food Chemistry 93, 253–263.
Aviara NA, Power PP, Abbas T. 2013. Moisture-dependent physical properties of Moringa oleifera seed relevant in bulk handling and mechanical processing. Industrial Crops and Products 42, 96–104.
Mohsenin NN. 1986. Physical Properties of Plant and Animal Materials. Taylor and Francis, New York.
Goldstein IJ, Hay GW, Lewis BA, Smith F. 1965. Controlled Degradation of Polysaccharides by Periodate Oxidation, Reduction, and Hydrolysis, in Methods In Carbohydrate Chemistry, ed. R L Whistler, J N BeMiller and M L Wolfrom, Academic Press, New York. 5, 361–370.
Raja W, Bera K, Ray B. 2016. Polysaccharides from Moringaoleifera gum: structural elements, interaction with β-lactoglobulin and antioxidative activity. RSC Advances 6(79), 75699–75706.
Siddhuraju P, Becker K. 2003.Antioxidant Properties of Various Solvent Extracts of Total Phenolic Constituents from Three Different Agroclimatic Origins of Drumstick Tree (Moringa oleifera Lam.) Leaves, Journal of Agricultural and Food Chemistry 51(8), 2144–2155.
Luqman S, Srivastava S, Kumar R, Maurya AD, Chanda D. 2012. Experimental Assessment of Moringa oleifera Leaf and Fruit for Its Antistress, Antioxidant, and Scavenging Potential Using In Vitro and In Vivo Assays. Evidence-based complementary and alternative medicine:e CAM, 519084.
Devendra BN, Srinivas N, Prasad VSSL. Talluri Warna Latha PS. 2011. Antimicrobial activity of Moringa oleifera lam., leaf extract, against selected bacterial and fungal strains, International Journal of Pharma and Bio Sciences 2(3), 13-18.
Elgamily H, Moussa A, Elboraey A, El-Sayed H, Al-Moghazy M, Abdalla A. 2016. Microbiological Assessment of Moringa oleifera Extracts and Its Incorporation in Novel Dental Remedies against Some Oral Pathogens. Open access Macedonian journal of medical sciences 4, 585–590.
Oluduro AO. 2012. Evaluation of Antimicrobial properties and nutritional potentials of Moringa oleifera Lam. leaf in South-Western Nigeria, Malaysian Journal of Microbiology 8(2), 59-67.
Jayaprakash Kuzhandaivel, Balamurugan Vadivel, Rajasekar Aruliah (2023), Antimicrobial and antioxidant properties of silver nanoparticles from Moringa oleifera gum: a green synthesis approach; IJB, V22, N4, April, P23-31
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