Antimicrobial and antioxidant properties of silver nanoparticles from Moringa oleifera gum: a green synthesis approach

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Research Paper 05/04/2023
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Antimicrobial and antioxidant properties of silver nanoparticles from Moringa oleifera gum: a green synthesis approach

Jayaprakash Kuzhandaivel, Balamurugan Vadivel, Rajasekar Aruliah
Int. J. Biosci.22( 4), 23-31, April 2023.
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Plant gums have enormous medicinal potential and have been used in the pharmaceutical and biomedical fields. In the present investigation, Moringa oleifera gum (MOG) was collected, and its physical properties and phytochemical composition were investigated. Silver nanoparticles (AgNPs) were produced, and characterization was carried out using UV spectroscopic analysis and scanning electron microscopy (SEM). In this study, the standard method was used for the antioxidant assay and the antimicrobial test. The synthesized nanoparticles (NPs) have irregular shapes and no fixed geometry. The agglomerate shape resembles that of pebble-like structures. UV‒vis analysis proved the wavelength of the sample to be 350–470 nm. In antioxidant studies, the synthesized AgNPs exhibited significant DPPH radical scavenging activity values ranging from 21.15 ± 0.017 to 63.46± 0.03 g/mL at concentrations ranging from 100 to 500 g/mL. In an antimicrobial experiment, the maximum incubation zone was 18 mm by 100 µL of AgNPs synthesized from M. oleifera gum extract against S. typhi. P. aeruginosa expressed a 16 mm zone of incubation at 100 µL of AgNPs synthesized from M. oleifera gum. According to the findings of this study, AgNPs derived from M. oleifera gum can be employed as a lead chemical in the creation of an effective antimicrobial drug for the treatment of microbial infections. This research establishes the foundation for synthesizing AgNPs from M. oleifera gum and its powerful novel pharmacological applications.


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