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Antimicrobial susceptibility and frequency of methicillin-resistant Staphylococcus aureus (MRSA) isolated from skin infected patients in District Peshawar, KPK, Pakistan

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Research Paper 01/09/2018
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Antimicrobial susceptibility and frequency of methicillin-resistant Staphylococcus aureus (MRSA) isolated from skin infected patients in District Peshawar, KPK, Pakistan

Iqbal Hussain, Saba, Muhammad Junaid, Rahim Dost Khan, Safia Hameed, Nasir Ali, Sifatullah
Int. J. Biosci.13( 3), 223-228, September 2018.
Certificate: IJB 2018 [Generate Certificate]
Key: AntibiogramAntibioticsMRSAMSSAS. aureus

Abstract

Staphylococcus aureus (S. aureus) is an important pathogen which causes community associated Methicillin-resistant Staphylococcus aureus in fection (CA-MRSA) and hospital-associated Methicillin-resistant Staphylococcus aureus (HA-MRSA). The objective of the current study was to investigate the frequency and antimicrobial susceptibility of MRSA isolated from clinical settings of Peshawar. Clinical samples including pus and swab were collected, followed by identification of MRSA by microscopic and biochemical based methods. Out of 97 isolates, (27%) were found positive. The frequency of MRSA strains was more in females (57%) than in males (43%). S. aureus was more prevalent in the age group 31-45 years with 42% followed by the age groups 46-60, 16-30 and 1-15 years with 26%, 18%,and 14% respectively. S. aureus showed high resistance to Oxacillin (27%), followed by Clarithromycin (18%), Amikacin and Doxycycline (16%), vancomycin (15%), Cefoxitin (13%), Amoxicillin (12%), linezolid (8%) and Sulzone (7%). The present study highlighted that linezolid and Sulzone were most effective to treat S. aureus infected patients.

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