Bioassay assessment of Catharanthus roseus flower flavonoids: In vitro study
Paper Details
Bioassay assessment of Catharanthus roseus flower flavonoids: In vitro study
Abstract
Catharanthus roseus commonly known as periwinkle has a rich story in traditional medicine. Researchers isolated two flavonoid compounds, Quercetin and Rutin from the methanolic extract of its flower. These compounds were evaluated for their cytotoxic, antibacterial and antioxidant properties. In the brine shrimp lethality bioassay, Quercetin exhibited quite potent activity with an LC50 (6.52) suppressing Rutin (5.05) μg/ml. Additionally, Quercetin demonstrated strong antibacterial effects against pathogenic microorganism compared to streptomycin, while Rutin displayed significant antioxidant activity with an IC50 10.86μg/ml. In addition, this bioassay assessment of Catharanthus roseus flower flavonoids is firstly reported in the present study.
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Shahin Aziz, 2024. Bioassay assessment of Catharanthus roseus flower flavonoids: In vitro study. J. Biodiv. Environ. Sci., 25(6), 18-24.
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