Biotransformation of ethyl p-methoxycinnamate from Kaempferia galanga L. using Aspergillus niger
Paper Details
Biotransformation of ethyl p-methoxycinnamate from Kaempferia galanga L. using Aspergillus niger
Abstract
Studies were carried out on the extraction of the rhizome of Kaempferia galanga L. using steam distillation and supercritical fluid extraction (SFE). After purification, the major compound of the K. galanga L. extract, ethyl p-methoxycinnamate (EPMC) was identified by NMR and MS spectrometry. Biotransformation of EPMC using Aspergillus niger afforded ethyl p-hydroxycinnamate in 24% yield.
Achuthan CR, Padikkala J. 1997. Hypolipidemic effect of Alpinia galanga (Rasna) and Kaempferia galangal (Kachoori). Indian Journal of Clinical Biochemistry 12, 55-58. http://dx.doi.org/10.1007/BF02867956
Barbosa-Filho JM, Lima CSA, Amorim ELC, de Sena KXFR, Almeida JRGS, da-Cunha EVL, Silva MS, de Fatima Agra M, Braz-Filho R. 2004. Botanical study, phytochemistry and antimicrobial activity of Tabebuia aurea. Revista Internacional de Botanica Experimental 53, 221-228.
Choochote W, Kanjanapothi D, Panthanga A, Taesotikul T, Jitpakdi A, Chaithong U, Pitasawat B. 1999. Larvicidal and repellent effects of Kaempferia galanga. The Southeast Asian Journal of Tropical Medicine and Public Health 30, 470-476.
Choudhary MI, Musharraf SG, Sami A, Atta-ur-Rahman. 2004. Microbial Transformation of (-)-Ambrox and Sclareolide. Helvetica Chimica Acta 87, 2685-2694. http://dx.doi.org/10.1002/hlca.200490238
De Abreu MB, Piaz FD, Temraz A, De Tommasi N, Braca A. 2010. Cyclobutane dimer iridoids from Tabebuia argentea Britt. (Bignoniaceae). Planta Medica 76, SL 56. http://dx.doi.org/10.1055/s-0030-1264294
De Pooter HL, Omar MN, Coolseat BA, Schamp NM. 1985. The essential oil of Greater Galanga (Alpinia galanga) From Malaysia. Phytochemistry 24, 93-96. http://dx.doi.org/10.1016/S0031-9422(00)80814-6
Ekowati J, Rudyanto M, Sasaki S, Budiati T, Sukardiman, Hermawan A, Meiyanto E. 2010. Structure modification of Ethyl-p methoxycinnamate isolated from Kaempferia Galanga L. and cytotoxicity Assay of the products on WiDr Cells. Indonesian Journal of Cancer Chemoprevention 1, 12-18.
Gouiric SC, Feresin GE, Tapia AA, Rossomando PC, Schmeda-Hirschmann G, Bustos DA. 2004. –Dihydroxydehydroabietic acid, a new biotransformation product of dehydroabietic acid by Aspergillus niger. World Journal of Microbiology & Biotechnology 20, 281–284. http://dx.doi.org/10.1023/B:WIBI.0000023834.60165.79
Kanjanapothi D, Panthong A, Lertprasertsuke N, Taesotikul T, Rujjanawate C, Kaewpinit D, Sudthayakorn R, Choochote W, Chaithong U, Jitpakdi A, Pitasawat B. 2004. Toxicity of crude rhizome extract of Kaempferia alanga L. (Proh Hom). Journal of Ethnopharmacology 90, 359-365. http://dx.doi.org/10.1016/j.jep.2003.10.020
Liu B, Liu F, Chen C, Gao H. 2010. Supercritical carbon dioxide extraction of ethyl p methoxycinnamate from Kaempferia galanga L. rhizome and its apoptotic induction in human HepG2 cells. Natural Product Research 24, 1927-1932. http://dx.doi.org/10.1080/14786419.2010.490913
Omar MN, Razman S, Nor-Nazuha MN, Muhammad-Nazreen MN, Zuberdi AM. 2013. Supercritical Fluid Extraction (SFE) of Malaysian Wild Ginger Zingiber puberulum Inflorescence. Oriental Journal of Chemistry 29, 89-92.
Othman R, Ibrahim H, Mohd MA, Awang K, Gilani AV, Musthafa MR. 2002. Vaso Relaxant Effect of Kaempferia galanga on Smooth Muscles of Rat Aorta. Planta Medica 68, 655–657. http://dx.doi.org/10.1055/s-2002-32900
Othman R. 1998. Chemical and Pharmacological studies on chemical constituent of Kaempferia Galanga L. Master’s thesis, University of Malaya. Malaysia.
Samsudin MW, Omar MN, Din L. 1989. Studies on the essential oils from Zingiber officinale, Alpinia galanga and Kaemferia galanga (Zingiberaceae) grown in Malaysia. In Othman M, ed. Research and Development in Physical and Applied Sciences. Bangi, Selangor, Malaysia, Penerbit Universiti Kebangsaan Malaysia, 153-160.
Schmeda-Hirschmann G, Aranda C, Kurina M, Rodriguez JA, Theoduloz C. 2007. Biotransformations of imbricatolic acid by Aspergillus niger and Rhizopus nigricans cultures. Molecules 12, 1092-1100. http://dx.doi.org/10.3390/12051092
Srivastava S, Luqman S, Fatima A, Darokar MP, Negi AS, Kumar JK, Shanker K, Chanotiya CS, Tandon S, Khanuja SPS. 2008. Biotransformation of Artemisinin Mediated through Fungal Strains for Obtaining Derivatives with Novel Activities. Scientia Pharmeceutica 77, 87–95. http://dx.doi.org/10.1038/npre.2012.6925.1
Vimala S, Norhanom AW, Yadav M. 1999. Anti-tumour promoter activity in Malaysian ginger rhizobia used in traditional medicine. British Journal of Cancer 80, 110-116. http://dx.doi.org/10.1038/sj.bjc.6690329
Wang Y, Tan TK, Tan GK, Connolly JD, Harrison LJ. 2009. Microbial transformation of the sesquiterpenoid (−)-maaliol by Mucor plumbeus. Tetrahedron 65, 5680-5683. http://dx.doi.org/10.1016/j.tet.2009.05.035
Nor Hazwani Mohd Hasali, Muhammad Nor Omar, Ahmad Muzammil Zuberdi, Helmi Yousif AlFarra (2013), Biotransformation of ethyl p-methoxycinnamate from Kaempferia galanga L. using Aspergillus niger; IJB, V3, N7, July, P148-155
https://innspub.net/biotransformation-of-ethyl-p-methoxycinnamate-from-kaempferia-galanga-l-using-aspergillus-niger/
Copyright © 2013
By Authors and International
Network for Natural Sciences
(INNSPUB) https://innspub.net
This article is published under the terms of the
Creative Commons Attribution License 4.0