Clostridium perfringens as a pathogenic organism in poultry

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Review Paper 01/09/2019
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Clostridium perfringens as a pathogenic organism in poultry

Ramla Achakzai, Muhammad Kamran Taj, Ferhat Abbas, Imran Taj, Syeda Ayesha Ali, Ahsanullah, Ashiq Hussain, Saima Azam, Zohra Samreen, Sakina Khan, Lal Bibi, Bibi Sazain, Saqiba Jogezai
Int. J. Biosci.15( 3), 55-65, September 2019.
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Clostridium perfringens causes necrotic enteritis (NE) disease in poultry. Necrotic enteritis has re-emerged as an important disease of poultry in recent years. The use of antimicrobials in poultry feeds has been attributed as one of the main contributing factors for the increasing incidence of necrotic enteritis in commercial poultry. Mortality due to NE is1% which results in great economic losses. Economic losses due to NE are not only associated with mortality but also associated with decreases in bird performance particularly in subclinical cases of NE. Birds that survive usually have a reduced ability to digest and absorb nutrients due to extensive damage to the mucosal lining, which ultimately results in reduced profitability. The poultry industry has been trying to reduce or eliminate the inclusion of sub therapeutic doses of antimicrobials into feed. Formulating diets not only meet bird’s nutrient requirements for growth but is also important for gastrointestinal health parameters. Maintenance and enhancement of intestinal integrity is essential for bird performance when antimicrobials are not included in feed, as commercial poultry face numerous enteric pathogen challenges. The most cost-effective control will probably be achieved by balancing the composition of the feed.


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