Effect of individualized weight loss program on fasting Interleukin 6 levels in obese adult subjects

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Research Paper 01/02/2014
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Effect of individualized weight loss program on fasting Interleukin 6 levels in obese adult subjects

Eizadi Mojtaba, Samarikhalaj Hamidreza, Kiani Fatemeh, Dooaly Hossein
J. Bio. Env. Sci.4( 2), 165-170, February 2014.
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Inflammation is hypothesized to play a central role in obesity and its related diseases; although the molecular mechanisms for this are less understood. Twenty-four healthy adult obese men were enrolled for this study through local advertising. The objective of study was to investigation of serum interleukin-6 response to long term exercise training in mentioned subjects that divided to exercise or control group. Subjects in exercise group were completed three months aerobic training and control subject did not participate in exercise program. Pre and post training of anthropometrical markers and fasting serum IL-6 were measured in two groups. Paired samples T test was used to determine significant difference between per and post values. Serum IL-6 levels were significantly increased in exercise group (from 2.77±0.24 to 3.36±0.41 pg/ml p<0.0001) and did not change in control group. All anthropometrical markers decreased after exercise program in exercise group (p ≤ 0.05). In conclusion, serum IL-6 response to exercise training is appears to be independent of weight status.


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