Efficacy of Pylorin (poly herbal formulation) for the management non Ulcer condition of stomach and H. Pylori limited Dyspepsia

Paper Details

Research Paper 01/06/2021
Views (738)
current_issue_feature_image
publication_file

Efficacy of Pylorin (poly herbal formulation) for the management non Ulcer condition of stomach and H. Pylori limited Dyspepsia

Syed Zahoor ul Hassan Zaidi, Ejaz Mohiuddin, Asif Iqbal, Shahabuddin
Int. J. Biosci. 18(6), 65-71, June 2021.
Copyright Statement: Copyright 2021; The Author(s).
License: CC BY-NC 4.0

Abstract

More than half of the world population present with the varying degree of dyspeptic situation in gastroenterology setting in health care system, available options of medications has not shown long term control over the ailment if there is, after some time relapse of the disease. In current era need for the development of alternate option to relief dyspepsia symptom has got much importance, dyspepsia affects more than 50% of the world population in majority of the cases it is not associated with identifiable lesion like H. pylori infection otherwise it’s eradication may spontaneously relive this ailment.This study was carried out for the assessment of the efficacy of the poly herbal formulation Pyorin for the management of dyspepsia in non-ulcer cases.Study was randomized single blind multicenter parallel arm study, carried at Shafa ul Mulk Memorial Hospital for Eastern Medicine, Hamdard University Karachi. All the process of Pylorin preparation was carried out at Hamdard University Karachi. Overall 670 total participants were enrolled in the study, 330 patients who receive Pylorin   comprise 138 female and 192 male. 264(80%) patients got complete relief, 49(15%) patients report only mild relief in their symptom while 17(5%) cases show no improvement. While in case of placebo only 27 cases shows marked improvement out of 340 cases rest of the cases shows mild improvement. Hence Pylorin can be used to manage H. Pylori limited dyspepsia.

Barbara L, Camilleri M, Corinaldesi R, Crean G, Heading R, Johnson A, Malagelada J, Stanghllini V, Wienbeck M. 1989. Definition and investigation of dyspepsia. Digestive diseases and sciences 34, 1272- 1276.

Coon JT, Ernst E.  2002. Systematic review herbal medicinal products. Alimentery Pharmacology  Therapeutics  16, 1689- 1699.

Desai  H. 2012. Dyspepsia. Journal of the Association of  Physicians of India 60, 5.

Harmon RC, Peura DA. 2010. Evaluation and management of dyspepsia. Therapeutic Advances in Gastroenterology 3, 87- 98.

Jones MP.  2019. Evaluation and treatment of dyspepsia. Postgraduate  Medical Journal 79, 25-29.

Ko SJ, Park JW, Lee JH, Cho SH, lee J, Nam S, Kim J. 2018. Herbal medicine Yukgunja-tang for functional dyspepsia protocol for a systematic review of randomized controlled trials. Medicine (Baltimore) 97, e12555.

Koduru  P, Irani M, Quigley EMM.  2018.  Definition, Pathogenesis, and Management. Clinical Gastroenterology and Hepatology  16, 467-479.

Moayyedi PM, Lacy BE, Andrews CN, EnnsRA, Howden CW,  Vakil N. 2017. ACG and CAG Clinical Guideline: Management of Dyspepsia. Amrecan  Journal of  Gastroenterology 112, 988-1013.

Suzuki H. 2018. New Medical Approach to Functional. Digestion 97, 6-12.

Tack J, Bbisschops R, Sarnelli G. Pathophysiology and Treatment of Functional Dyspepsia.

Talley  NJ. 2017. Functional Dyspepsia: Advances in Diagnosis and therapy. GUT and Liver  11, 349-357.

Vakil  NB, Howden, Moayyedi P, Tack J. 2017. White Paper AGA Functional Dyspepsia. Clinical Gastroenterology and Hepatology 15.

Related Articles

Evaluating the ecophysiological response of marine fungi to textile dye degradation potential

S. Sathya, G. Kanimozhi, A. Panneerselvam, Int. J. Biosci. 27(3), 12-21, September 2025.

Phytochemical analysis and antibacterial activity of Biophytum sensitivum

H. P. Reni Christabel, T. S. Dhanaraj, V. Ramamurthy, Int. J. Biosci. 27(2), 300-305, August 2025.

Phytochemical and antibacterial screening of different solvent extracts of Mentha spicata

V. R. Rakhi, T. S. Dhanaraj, V. Ramamurthy, Int. J. Biosci. 27(2), 280-286, August 2025.

Physico-chemical characterization of soils in two peri-urban lowlands: Implications for the sustainability of rice cultivation in Korhogo (northern Côte d’Ivoire)

Konan Kouamé Firmin, Nangah Krogba Yves, Touré Béssimory, Coulibaly Tchowa Bintou, Kouassi Anoma Jonathan Christian, Bayala Roger, Bakayoko Sidiky, Int. J. Biosci. 27(2), 270-279, August 2025.

Yield performance assessment of different mustard cultivars under field conditions

Md. Khan Jahan Ali, Md. Moshiur Rahman, Kamrun Nahar, Sharmin Ara Jannat, Mst. Khadija Khatun, Sushan Chowhan, Md. Habibur Rahman, Int. J. Biosci. 27(2), 264-269, August 2025.

Species composition of xylomicobiota of some woody plants distributed in Azerbaijan

K. F. Bakhshaliyeva, V. Y. Hasanova, N. R. Namazov, B. N. Aliyeva, S. C. Garayeva, S. E. Nagiyeva, P. Z. Muradov, Int. J. Biosci. 27(2), 254-263, August 2025.