Epidemiological studies of antibiotic resistance in pathogens isolated from blood cultures of people from Cuddalore District

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Research Paper 17/03/2023
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Epidemiological studies of antibiotic resistance in pathogens isolated from blood cultures of people from Cuddalore District

C. Uma Maheswari, V. Arul Balaji, J. Vigneshwari,G. Vinitha, M. Shenbagam
Int. J. Biosci.22( 3), 51-55, March 2023.
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Abstract

Infections due to multidrug-resistant (MDR) microorganisms have triggered antimicrobial resistance among the antibiotics pattern. Antimicrobial resistance (AMR) in pathogens isolated from blood cultures is currently one of the most concerning issues in medicine. This study was to investigate the AMR distribution of the blood-borne pathogens isolated over two years in the Cuddalore region. A surveying laboratory-confirmed bloodstream infection (BSIs) was done and data from various major diagnostic laboratories were used. During the study period, 390 positive BSIs were collected. The prevalence of gram-positive bacteria (51%) and gram-negative bacteria (49%). The most common pathogens were gram-positive isolates Staphylococcus haemolyticus (38%) and Staphylococcus home. hominis (31%) and gram-negative isolates Enterobacter cloacae complex (13%), Acinetobacter haemolyticus and Klebsiella pneumonia (18%). The gram-positive Staphylococcus haemolyticus and Staphylococcus hom. hominis showed the highest resistance and sensitivity antibiotics pattern. Tigecycline was a highly sensitive antibiotic against all gram-positive isolates. Citro. Koseri showed sensitivity among the gram-negative antibiotic pattern. High resistance rates to both frontline antibiotics were observed for all gram-positive organisms isolated from blood cultures.

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