Ethanolic Clerodendrum inerme leaf extract: UV, FTIR spectroscopy and phytochemical screening
Paper Details
Ethanolic Clerodendrum inerme leaf extract: UV, FTIR spectroscopy and phytochemical screening
Abstract
One significant medicinal herb is Clerodendrum inerme. The plant is referred to locally as “bonjol” in Bangladesh. The current study examines the ethanolic seed extract of this plant using UV and FT-IR spectroscopy as well as phytochemical screening. The plant has anti-inflammatory, anti-cancer, anti-malarial, antidiabetic, and antioxidant qualities. A group of phytochemicals like flavonoids, terpenoids glycosides, phytosterols, etc. are all present in the extract according to phytochemical screening. Carbonyl group (ketone), α,β unsaturated amides, lactams, sulfur compounds, nitro compounds, flavones, fistins, quercetins, Sodium Salts of Quercetin 5′ Sulfonic Acid, myricetins, chalcones, flavonoids (anthocyanin type) are detected by UV and Fourier Transform and Infra-Red spectroscopy of the plant’s ethanolic leaf extract. The bioactive compounds mentioned above primarily contribute to the plant’s therapeutic properties.
Bohm BA. 1998. Introduction to flavonoids. Harwood Academic Publishers, Canada, 200–202.
Brickell C, Zuk JD. 1997. The American Horticultural Society A-Z encyclopedia of garden plants. DK Publishing, Inc., NY.
Caius JF. 1986. The medicinal and poisonous plants of India. Scientific Publishers, Jodhpur, India, 457–458.
Cooke T. 1958. Flora of the Presidency of Bombay. Botanical Survey of India, Calcutta 1, 1–120. https://doi.org/10.5962
Durry CH. 2010. Ayurvedic useful plants of India. 2nd ed. Asiatic Publishing House, Delhi, 184.
Dutta M. 2000. Infrared spectroscopy. IVY Publishing House, Sarup & Sons, New Delhi.
George M, Pandalai KM. 1949. Investigations on plant antibiotics, Part IV. Further search for antibiotic substances in Indian medicinal plants. Indian Journal of Medical Research 37, 169–181.
Gupta SP, Siddhant S, Gopal G. 2010. Clerodendron inerme: An update of its indigenous uses, phytochemistry and pharmacology. International Journal of Chemical Sciences 8(1), 203–212.
Harish SR, Murugan K. 2011. Biochemical & genetic variation in the mangrove associate Clerodendron inerme (L.) Gaertn. under different habitats of Kerala. Asian Journal of Experimental Biological Sciences 2(4), 553–561.
Harwood LM, Moody CJ. 1989. Experimental organic chemistry: Principles and practice. Wiley-Blackwell, 122–125. ISBN: 0-632-02017-2.
Heneczkowski M, Kopacz M, Nowak D, Kuzniar A. 2001. Infrared spectrum analysis of some flavonoids. Acta Poloniae Pharmaceutica – Drug Research 58(6), 415–420.
Kaushik P, Dhiman AK. 1999. Medicinal plant and raw drugs of India. Bishen Singh Mahendra Pal Singh Publication, Dehra Dun, 126–127.
Kothari A, Harish P, Shrivastava N. 2006. Ex situ conservation method for Clerodendrum inerme: A medicinal plant of India. African Journal of Biotechnology 5(5), 415–418. https://doi.org/10.5897/AJB05.319
Krishnan Marg KS. 2001. The wealth of India. National Institute of Science Communication, CSIR, New Delhi 2, 67–68.
Manoharan S, Kavitha K, Senthil N, Renju GL. 2006. Evaluation of anticarcinogenic effects of Clerodendron inerme. Singapore Medical Journal 47(12), 1038–1043.
Masuda T, Yonemori S, Oyama Y, Takeda Y, Tanaka T, Andoh T, Shinohara A, Nakata M. 1999. Evaluation of the antioxidant activity of environmental plants: Activity of the leaf extracts from seashore plants. Journal of Agricultural and Food Chemistry 47, 1749–1754. DOI: 10.1021/JF980864S
Mehdi H, Tan GT, Pezzuto JM, Fong HHS, Farnsworth NR, El Feraly FS. 1997. Cell culture assay system for the evaluation of natural product-mediated anti-hepatitis B virus activity. Phytomedicine 3, 369–377. DOI: 10.1016/S0944-7113(97)80011-6
Neeta S, Tejas P. 2007. Clerodendrum and healthcare: An overview. Medicinal and Aromatic Plant Science and Biotechnology 1(1), 142–150. http://internationaljournalofresearch.org
Rajasekaran A, Ponnusamy K. 2006. Antifungal activity of Clerodendrum inerme (L). Turkish Journal of Biology 30, 139–142. https://www.researchgate.net/publication/235706085
Richa P, Ram KV, Gupta MM. 2005. Neo-clerodane diterpenoids from Clerodendrum inerme. Phytochemistry 66, 643–648. DOI: 10.1016/j.phytochem.2004.11.007
Saraswathi MN, Karthikeyan M, Kannan M, Rajasekar S. 2012. Terminalia belerica Roxb – A phytopharmacological review. International Journal of Research in Pharmacy and Biosciences 3(1), 96–99. http://indianmedicine.eldoc.ub.rug.nl/id/eprint/68054
Shahin A, Koushik S, Nasim S, Shamim A, Abdullah AM. 2014. Phytochemical and elemental screening on leaves and flowers of Catharanthus roseus: An important medicinal plant in Bangladesh. International Journal of Chemical Sciences 12(4), 1328–1336.
Shanmugam M, Kannan K, Subramanian B, Kashinathan R. 2008. Clerodendron inerme protects cellular integrity during 7,12-dimethylbenz[a]-anthracene induced hamster buccal pouch carcinogenesis. African Journal of Traditional, Complementary and Alternative Medicines 5(2), 213–222. DOI: 10.4314/ajtcam.v5i2.31276
Sharma SK, Singh VP. 1979. The antifungal activity of some essential oils. Indian Drugs and Pharmaceutical Industry 14, 3–6. DOI: 10.1021/jf0344082
Somasundram S, Sadique J. 1986. Anti-hemolytic effect of flavonoidal glycosides of C. inerme: An in vitro study. Fitoterapia 57, 103–110.
Shahin Aziz, Md. Morshed Alam, Sharika Farhana (2025), Ethanolic Clerodendrum inerme leaf extract: UV, FTIR spectroscopy and phytochemical screening; IJB, V26, N4, April, P127-133
https://innspub.net/ethanolic-clerodendrum-inerme-leaf-extract-uv-ftir-spectroscopy-and-phytochemical-screening/
Copyright © 2025
By Authors and International
Network for Natural Sciences
(INNSPUB) https://innspub.net
This article is published under the terms of the
Creative Commons Attribution License 4.0